70,514 research outputs found
Modelling and optimal control of plate evaporators
Evaporators are an important stage in the extraction of sugar from sugar cane. A model of a simple evaporator is developed and then extended to multiple stage evaporation. An approximate solution and an iterative solution to the equations are developed. From the properties of these models a control strategy is developed
IPOs and the Slow Death of Section 5
Since its enactment, Section 5 of the Securities Act of 1933 has restricted sales-based communications with investors, but that effort is nearly dead even with respect to the most sensitive of offerings, the IPO. Our paper traces that devolution, which began almost as soon as the â33 Act came into existence, though the SECâs 2005 deregulatory reforms and Congressâ intervention in the JOBS Act of 2012. We show how much of this related to an embrace of âbook-buildingâ as the industryâs preferred method of price discovery, which requires private two-way communications between underwriters and potential sophisticated investors. But book-building (and the predictable IPO underpricing that results) has a retail dimension as well, and we point to ways in which the otherwise sensible deregulation may enable an over-stimulation of retail investor demand. We then explore two main justifications that have been given for the aggressive deregulation. The first is that any loss in prophylactic protection can be made up for by the threat of liability, particularly with an enhanced Section 12(a)(2). We find this unpersuasive for a variety of reasons. The otherâamply visible in the long history of Section 5âis a faith in the âfiltrationâ process, that retail investors gain protection because of the availability of the preliminary prospectus during the waiting period, to those involved in the selling process if not the investors themselves. Putting aside the biased incentives that affect filtration, much of what is most importantâand conveyed privately to the institutions in the course of book-buildingâis forward-looking information that probably need not appear in the formal disclosure, whether preliminary or final. None of this is an argument for returning to the old prophylactics of Section 5. But it is cause for the SEC and FINRA to pay close attention to the retail investor effects of the IPO selling practices, especially in the post-JOBS Act era
âPublicnessâ in Contemporary Securities Regulation after the JOBS Act
The JOBS Act of 2012 reflects the largest deregulatory change to the Securities Exchange Act of 1934 over its more than 75 year history. It contracts the coverage of those companies subject to the obligations of âpublicnessâ and it introduces an âon rampâ that will permit most newly-public companies to meet a lesser set of disclosure, internal control and governance obligations for up to five years. We set these changes against a larger discussion of when a private enterprise should be forced to take on public status in securities regulation, a topic that has been entirely under theorized. We conclude that the change from 500 to 2000 shareholders of record made by the JOBS Act, while entirely clear in its deregulatory thrust, misses a key point: ârecordâ ownership is an antiquated metric for any measuring of publicness and Congress needs to find a better one, such as public trading. More broadly, we observe that Congress increasingly has defined public obligations in securities regulation less by the traditional touchstone of investor protection and more by ways that our largest companies affect constituencies beyond their investor base. Our boundary-setting thus should include two tiers of public companies with the smaller tier limited to core disclosure and governance obligations. Finally, our review of these boundary questions reveals a larger pattern that ought to inform how we understand securities regulation. Entrepreneurs and their advisors regularly occupy new unregulated space created in the wake of technological change or by gaps in regulation revealed as markets evolve. Government response, seemingly inevitably, is piecemeal and reactive. The result is a regulatory process that is more informal than administrative law theory usually suggests and more opaque than we might want in contemplating regulatory change
Opioid stimulation in the ventral tegmental area facilitates the onset of maternal behavior in rats
This research investigated the effect of an increase or decrease in opioid activity in the ventral tegmental area (VTA) on the onset of maternal behavior in rats. In Experiment 1, the latency to show maternal behavior toward foster rat pups (sensitization latency) was determined in maternally naive female rats given either nothing or a unilateral intra-VTA injection of morphine sulfate (MS) (0.0, 0.01, 0.03, 0.1 or 0.3 ”g), on the first three days of a 10-day period of constant exposure to pups. Rats treated with 0.03 ”g MS had significantly shorter sensitization latencies than did rats treated with 0.0 ”g MS, 0.01 ”g MS, or receiving no treatment (higher doses of morphine produced intermediate results). The facilitating effect of intra-VTA MS on the onset of maternal behavior was blocked by pretreatment with naltrexone hydrochloride and was found to have a specific site of action in the VTA (MS injections dorsal to the VTA were ineffective). In Experiment 2, sensitization latencies were determined in periparturitional rats given a bilateral intra-VTA injection of either the opioid antagonist naltrexone methobromide (quaternary naltrexone), its vehicle, a sham injection, or left untreated 40 min after delivery of the last pup. The mothers' own pups were removed at delivery; mothers were nonmaternal at the time of testing. Quaternary naltrexone treatment produced significantly slower sensitization to foster pups than did control conditions. Total activity and pup-directed activity did not differ significantly with treatment. The results demonstrate that increased opioid activity in the VTA facilitates the onset of maternal behavior in inexperienced nonpregnant female rats, and decreased opioid activity in the VTA disrupts the rapid onset of maternal behavior at parturition
Global Seismic Oscillations in Soft Gamma Repeaters
There is evidence that soft gamma repeaters (SGRs) are neutron stars which
experience frequent starquakes, possibly driven by an evolving, ultra-strong
magnetic field. The empirical power-law distribution of SGR burst energies,
analogous to the Gutenberg-Richter law for earthquakes, exhibits a turn-over at
high energies consistent with a global limit on the crust fracture size. With
such large starquakes occurring, the significant excitation of global seismic
oscillations (GSOs) seems likely. Moreover, GSOs may be self-exciting in a
stellar crust that is strained by many, randomly-oriented stresses. We explain
why low-order toroidal modes, which preserve the shape of the star and have
observable frequencies as low as ~ 30 Hz, may be especially susceptible to
excitation. We estimate the eigenfrequencies as a function of stellar mass and
radius, and their magnetic and rotational shiftings/splittings. We also
describes ways in which these modes might be detected and damped. There is
marginal evidence for 23 ms oscillations in the hard initial pulse of the 1979
March 5th event. This could be due to the mode in a neutron star with B
~ 10^{14} G or less; or it could be the fundamental toroidal mode if the field
in the deep crust of SGR 0526-66 is ~ 4 X 10^{15} G, in agreement with other
evidence. If confirmed, GSOs would give corroborating evidence for
crust-fracturing magnetic fields in SGRs: B >~ 10^{14} G.Comment: 12 pages, AASTeX, no figures. Accepted for Astrophysical Journal
Letter
Ingestion of Amniotic Fluid Enhances\ud Opiate Analgesia in Rats
Placenta ingestion has recently been shown to enhance opiate-mediated analgesia produced by morphine injection, footshock, or vaginal/cervical stimulation. The enhancement of the effect of endogenous opiates (especially analgesia) may be one of the principal benefits to mammalian mothers of placentophagia at delivery. During labor and delivery, however, mothers also ingest amniotic fluid (AF) which, unlike placenta, becomes available during, or even before expulsion of the infant. The present experiments were undertaken to determine (a) whether AF ingestion, too, enhances analgesia; if so, (b) whether the effect requires ingestion of, or merely exposure to, AF; (c) whether the effect can be produced by AF delivered directly to the stomach by tube; and (d) whether the enhancement, if it exists, can be blocked by administering an opiate antagonist. Nulliparous Long-Evans rats were tested for analgesia using tail-flick latency. We found that (a) rats that ingested AF after receiving a morphine injection showed significantly more analgesia than did rats that ingested a control substance;' (b) AF ingestion, alone, did not produce analgesia; (c) ingestion of AF, rather than just smelling and seeing it, was necessary to produce analgesia enhancement; (d) AF produced enhancement\ud
when oropharyngeal factors were eliminated by delivering it through an orogastric tube; and (e) treatment of the rats with naltrexone blocked the enhancement of morphine-induced analgesia that results from AF ingestion
Dose-Dependent Enhancement of Morphine-Induced Analgesia\ud by Ingestion of Amniotic Fluid and Placenta
Ingestion of amniotic fluid and placenta by rats has been shown to enhance opioid-mediated analgesia. The present studies were designed to examine the effect of several doses and volumes of placenta and amniotic fluid on tail-flick latency in rats treated with 3 mg/kg morphine. The optimal dose of amniotic fluid was found to be 0.25 ml, although 0.50 and 1.0 ml also produced significant enhancement. Doses of 0.125 and 2 ml of amniotic fluid were ineffective, as was a dose of 0.25 ml diluted to 2 ml with saline. The optimal dose of placenta was found to be 1 placenta, although the resulting enhancement was not significantly greater than that produced by 0.25, 0.50, 2.0 or 4.0 placentas. Doses smaller than 0.25 placenta or larger than 4.0 placentas were ineffective. The most effective doses of amniotic fluid and placenta correspond to the amounts delivered with each pup during parturition
Millipeds (Arthropoda: Diplopoda) of the Ark - La - Tex. VI. New Geographic Distributional Records from Select Counties of Arkansas
We continue to report, in the sixth of a series of papers, new geographic records for millipeds of the state, including noteworthy records for some taxa collected from Crowleyâs Ridge in eastern Arkansas. This contribution documents 47 new co. records and includes records for 19 species within 9 families and 5 orders. More uncommon millipeds found included Okliulus carpenteri (Parajulidae), Eurymerodesmus newtonus (Eurymerodesmidae), Pseudopolydesmus minor (Polydesmidae) and undescribed species of Ethojulus (Parajulidae) and Nannaria (Xystodesmidae). Undoubtedly, additional records will be reported in the future as several gaps in the distribution of Arkansas millipeds remain
Magnetars and pulsars: a missing link
There is growing evidence that soft gamma-ray repeaters (SGRs) and anomalous
X-ray pulsars (AXPs) are isolated neutron stars with superstrong magnetic
fields, i.e., magnetars, marking them a distinguished species from the
conventional species of spindown-powered isolated neutron stars, i.e., radio
pulsars. The current arguments in favor of the magnetar interpretation of
SGR/AXP phenomenology will be outlined, and the two energy sources in
magnetars, i.e. a magnetic dissipation energy and a spindown energy, will be
reviewed. I will then discuss a missing link between magnetars and pulsars,
i.e., lack of the observational evidence of the spindown-powered behaviors in
known magnetars. Some recent theoretical efforts in studying such behaviors
will be reviewed along with some predictions testable in the near future.Comment: Invited talk at the Sixth Pacific Rim Conference on Stellar
Astrophysics, a tribute to Helmut A. Abt, July 11-17, 2002, Xi'an. To appear
in the proceedings (eds. K. S. Cheng, K. C. Leung & T. P. Li
The Giant Flare of 1998 August 27 from SGR 1900+14: II. Radiative Mechanism and Physical Constraints on the Source
(ABBREVIATED) The extraordinary 1998 August 27 giant flare places strong
constraints on the physical properties of its source, SGR 1900+14. We make
detailed comparisons of the published data with the magnetar model. The giant
flare evolved through three stages, whose radiative mechanisms we address in
turn. A triggering mechanism is proposed, whereby a helical distortion of the
core magnetic field induces large-scale fracturing in the crust and a twisting
deformation of the crust and exterior magnetic field. The envelope of the
pulsating tail of the August 27 flare can be accurately fit, after ~40 s, by
the contracting surface of a relativistically hot, but inhomogeneous, trapped
fireball. We quantify the effects of direct neutrino-pair emission, thereby
deducing a lower bound ~ 10^{32} G-cm^3 to the magnetic moment of the confining
field. The radiative flux during the intermediate ~40 s of the burst appears to
exceed the trapped fireball fit. The spectrum and lightcurve of this smooth
tail are consistent with heating in an extended pair corona, possibly powered
by continuing seismic activity in the star. We consider in detail the critical
luminosity, below which a stable balance can be maintained between heating and
radiative cooling in a confined, magnetized pair plasma; but above which the
confined plasma runs away to local thermodynamic equilibrium. In the later
pulsating tail, the best fit temperature equilibrates at a value which agrees
well with the regulating effect of photon splitting. The remarkable four-peaked
substructure within each 5.16-s pulse provides strong evidence for the presence
of higher magnetic multipoles in SGR 1900+14. The corresponding collimation of
the X-ray flux is related to radiative transport in a super-QED magnetic field.Comment: 11 July 2001, accepted for publication in the Astrophysical Journa
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