Language-universal constraints on the segmentation of English

Two word-spotting experiments are reported that examine whether the Possible-Word Constraint (PWC) [1] is a language-specific or language-universal strategy for the segmentation of continuous speech. The PWC disfavours parses which leave an impossible residue between the end of a candidate word and a known boundary. The experiments examined cases where the residue was either a CV syllable with a lax vowel, or a CVC syllable with a schwa. Although neither syllable context is a possible word in English, word-spotting in both contexts was easier than with a context consisting of a single consonant. The PWC appears to be language-universal rather than language-specific

Virtual EQ – the talent differentiator in 2020?

In an increasingly competitive, globalised world, knowledge-intensive industries/ services are seen as engines for success. Key to this marketplace is a growing army of ‘talent’ i.e. skilled and dedicated knowledge workers. These knowledge workers engage in non-routine problem solving through combining convergent, divergent and creative thinking across organizational and company boundaries - a process often facilitated though the internet and social media, consequently forming networks of expertise. For knowledge workers, sharing their learning with others through communities of practice embedded in new information media becomes an important element of their personal identity and the creation of their individual brand or e-social reputation. Part of the new knowledge/skills needed for this process becomes not only emotional intelligence (being attuned to the emotional needs of others) but being able to do this within and through new media, thus the emergence of virtual emotional intelligence (EQ). Our views of current research found that HRD practitioners in 2020 might need to consider Virtual EQ as part of their talent portfolio. However it seems that new technology has created strategies for capturing and managing knowledge that are readily duplicated and that a talent differentiator in 2020 might simply be the ability and willingness to learn

A Topos Perspective on State-Vector Reduction

A preliminary investigation is made of possible applications in quantum theory of the topos formed by the collection of all $M$-sets, where $M$ is a monoid. Earlier results on topos aspects of quantum theory can be rederived in this way. However, the formalism also suggests a new way of constructing a `neo-realist' interpretation of quantum theory in which the truth values of propositions are determined by the actions of the monoid of strings of finite projection operators. By these means, a novel topos perspective is gained on the concept of state-vector reduction

Making automation pay - cost & throughput trade-offs in the manufacture of large composite components

The automation of complex manufacturing operations can provide significant savings over manual processes, and there remains much scope for increasing automation in the production of large scale structural composites. However the relationships between driving variables are complex, and the achievable throughput rate and corresponding cost for a given design are often not apparent. The deposition rate, number of machines required and unit production rates needed are interrelated and consequently the optimum unit cost is difficult to predict. A detailed study of the costs involved for a series of composite wing cover panels with different manufacturing requirements was undertaken. Panels were sized to account for manufacturing requirements and structural load requirements allowing both manual and automated lay-up procedures to influence design. It was discovered that the introduction of automated tape lay-up can significantly reduce material unit cost, and improve material utilisation, however higher production rates are needed to see this benefit

Topos-Theoretic Extension of a Modal Interpretation of Quantum Mechanics

This paper deals with topos-theoretic truth-value valuations of quantum propositions. Concretely, a mathematical framework of a specific type of modal approach is extended to the topos theory, and further, structures of the obtained truth-value valuations are investigated. What is taken up is the modal approach based on a determinate lattice \Dcal(e,R), which is a sublattice of the lattice \Lcal of all quantum propositions and is determined by a quantum state $e$ and a preferred determinate observable $R$. Topos-theoretic extension is made in the functor category \Sets^{\CcalR} of which base category \CcalR is determined by $R$. Each true atom, which determines truth values, true or false, of all propositions in \Dcal(e,R), generates also a multi-valued valuation function of which domain and range are \Lcal and a Heyting algebra given by the subobject classifier in \Sets^{\CcalR}, respectively. All true propositions in \Dcal(e,R) are assigned the top element of the Heyting algebra by the valuation function. False propositions including the null proposition are, however, assigned values larger than the bottom element. This defect can be removed by use of a subobject semi-classifier. Furthermore, in order to treat all possible determinate observables in a unified framework, another valuations are constructed in the functor category \Sets^{\Ccal}. Here, the base category \Ccal includes all \CcalR's as subcategories. Although \Sets^{\Ccal} has a structure apparently different from \Sets^{\CcalR}, a subobject semi-classifier of \Sets^{\Ccal} gives valuations completely equivalent to those in \Sets^{\CcalR}'s.Comment: LaTeX2

Evaluation of arts based courses within a UK recovery college for people with mental health challenges

No previous studies have evaluated arts based recovery college courses. Yet arts may assist in personal recovery, as often defined by service users, through social connection and personal meaning. This interdisciplinary study evaluated (i) whether self-reported wellbeing and arts activities increased following arts based recovery college courses, and (ii) how students, peer trainers and artist-trainers understood courses’ impact. The design was mixed-methods. Of 42 service-user students enrolling, 39 completed a course and 37 consented to provide data. Of these, 14 completed pre and post course questionnaires on mental wellbeing and 28 on arts participation. Post course focus groups were held with 6 of 8 peer-trainers and 5 of 7 artist-trainers, and 28 students gave written feedback. Twenty-four students were interviewed up to three times in the subsequent nine months. There were statistically significant increases in self-reported mental wellbeing and range of arts activities following course attendance. At follow-up 17 of 24 students reported improved mental wellbeing, while 7 reported little or no change. Some spoke of increased social inclusion and continuing to use skills learned in the course to maintain wellbeing. Initial in course experience of ‘artistic growth’ predicted follow-up reports of improvement. Future controlled studies should employ standardized measures of social inclusion and arts participation

Expansion of anti-AFP Th1 and Tc1 responses in hepatocellular carcinoma occur in different stages of disease

Copyright @ 2010 Cancer Research UK. This work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/.Background: α-Fetoprotein (AFP) is a tumour-associated antigen in hepatocellular carcinoma (HCC) and is a target for immunotherapy. However, there is little information on the pattern of CD4 (Th1) and CD8 (Tc1) T-cell response to AFP in patients with HCC and their association with the clinical characteristics of patients. Methods: We therefore analysed CD4 and CD8 T-cell responses to a panel of AFP-derived peptides in a total of 31 HCC patients and 14 controls, using an intracellular cytokine assay for IFN-γ. Results: Anti-AFP Tc1 responses were detected in 28.5% of controls, as well as in 25% of HCC patients with Okuda I (early tumour stage) and in 31.6% of HCC patients with stage II or III (late tumour stages). An anti-AFP Th1 response was detected only in HCC patients (58.3% with Okuda stage I tumours and 15.8% with Okuda stage II or III tumours). Anti-AFP Th1 response was mainly detected in HCC patients who had normal or mildly elevated serum AFP concentrations (P=0.00188), whereas there was no significant difference between serum AFP concentrations in these patients and the presence of an anti-AFP Tc1 response. A Th1 response was detected in 44% of HCC patients with a Child–Pugh A score (early stage of cirrhosis), whereas this was detected in only 15% with a B or C score (late-stage cirrhosis). In contrast, a Tc1 response was detected in 17% of HCC patients with a Child–Pugh A score and in 46% with a B or C score. Conclusion: These results suggest that anti-AFP Th1 responses are more likely to be present in patients who are in an early stage of disease (for both tumour stage and liver cirrhosis), whereas anti-AFP Tc1 responses are more likely to be present in patients with late-stage liver cirrhosis. Therefore, these data provide valuable information for the design of vaccination strategies against HCC.Association for International Cancer Research and Polkemmet Fund, London Clinic

When You And I Were Young, Maggie.

https://digitalcommons.library.umaine.edu/mmb-vp/2704/thumbnail.jp