2 research outputs found
Tuberculosis impacts multiple aspects in quality of life in a Romanian cohort of drugâsusceptible and drug resistant patients: A patientâreported outcome measures study
Background: Tuberculosis (TB), and especially its drug resistant forms, is responsible for not only significant mortality, but also considerable morbidity, still underâquantified. This study used four PatientâReported Outcome Measures (PROMS) to assess the status of persons affected by drugâsusceptible and drugâresistant TB during their TB treatment or after treatment completion, in Romania, the highest TB burden country in the EU.
Methods: People affected by TB in two different regions in Romania were included during and after treatment, following a crossâsectional design. PROMs used were SFâ36, EQâ5Dâ5L, WPAI and the appâbased audiometry screening tool âuHear.â Descriptive statistics and relevant statistical tests were used to compare groups between themselves and with the general Romanian population.
Results: Both patients with drugâsusceptible and drugâresistant TB experience, with drugâresistant patients experiencing statistically significantly more pain and hearing loss. PROMs show some improvement in the afterâtreatment group; however, compared with the general Romanian population for which data were available, all groups scored lower on all outcome measures.
Conclusion: PROMs offer the possibility of obtaining a more comprehensive view of patients' status, by involving them directly in the medical process and could guide a rehabilitation strategy