L’Antiquité tardive dans les collections médiévales. Textes et représentations, VIe-XIVe siècle, éd. Stéphane Gioanni et Benoît Grévin

Ce livre regroupe les textes issus de deux séminaires sur les constitutions de collections de textes entre Antiquité tardive et Moyen Âge en Europe occidentale. Le volume s’ouvre avec des remarques préliminaires des éditeurs sur la difficulté de définir ce qui constitue une « collection » : si l’on exclut les corpus d’œuvres d’un seul auteur, les textes sont généralement groupés en fonction d’un genre littéraire ou en vue de l’acquisition d’un savoir spécifique. L’introduction souligne la dif..

L’Antiquité tardive dans les collections médiévales. Textes et représentations, VIe-XIVe siècle, éd. Stéphane Gioanni et Benoît Grévin

Ce livre regroupe les textes issus de deux séminaires sur les constitutions de collections de textes entre Antiquité tardive et Moyen Âge en Europe occidentale. Le volume s’ouvre avec des remarques préliminaires des éditeurs sur la difficulté de définir ce qui constitue une « collection » : si l’on exclut les corpus d’œuvres d’un seul auteur, les textes sont généralement groupés en fonction d’un genre littéraire ou en vue de l’acquisition d’un savoir spécifique. L’introduction souligne la dif..

The Coptic Apocalypse of Paul, Irenaeus’ Adversus Haereses 2.30.7, and the second-century battle for Paul’s legacy

This article discusses the Coptic gnostic Apocalypse of Paul (NHC V,1), an expansion of Paul’s heavenly ascent as described in 2 Cor 12.2–4, arguing that its similarities to, and independence from, Irenaeus’ extrapolation of a Valentinian understanding of this ascension (Adversus Haereses 2.30.7) suggests that both accounts were written in a context of controversy between Valentinian and proto-orthodox Christians wherein both sides tried to claim the apostle Paul’s authority. It also argues that this proposed Sitz im Leben renders coherent certain aspects of the Apocalypse of Paul that have in the past been considered problematic .Subject Headings: Apocalypse of Paul (Coptic version) - Irenaeus, Saint, Bishop of Lyon. Adversus haereses. - Bible. N.T. Corinthians, 2nd -- Criticism, interpretation, etc. -- History -- Early church, ca. 30-600. - Paul, the Apostle, Saint

Guide to identifying alert thresholds for heat waves in Canada based on evidence

Among natural-disaster risks, heat waves are responsible for a large number of deaths, diseases and economic losses around the world. As they will increase in severity, duration and frequency over the decades to come within the context of climate change, these extreme events constitute a genuine danger to human health, and heat-warning systems are strongly recommended by public health authorities to reduce this risk of diseases and of excessive mortality and morbidity. Thus, evidence-based public alerting criteria are needed to reduce impacts on human health before and during persistent hot weather conditions.\ud The goal of this guide is to identify alert thresholds for heat waves in Canada based on evidence, and to propose an approach for better defining heat waves in the Canadian context in order to reduce the risks to human health and contribute to the well-being of Canadians. This guide is the result of the collaboration among various research and public institutions working on: 1) meteorological and climate aspects, i.e. the Meteorological Service of Canada (MSC, Environment and Climate Change Canada), and the ESCER centre at the Université du Québec à Montréal, and 2) public health, i.e. Health Canada and the Institut National de Santé Publique du Québec

Approaches to considering sex and gender in continuous professional development for health and social care professionals : an emerging paradigm

Consideration of sex and gender in research and clinical practice is necessary to redress health inequities and reduce knowledge gaps. As all health professionals must maintain and update their skills throughout their career, developing innovative continuing professional education programs that integrate sex and gender issues holds great promise for reducing these gaps. This article proposes new approaches to partnership, team development, pedagogical theory, content development, evaluation and data management that will advance the integration of sex and gender in continuing professional development (CPD). Our perspectives build on an intersectoral and interprofessional research team that includes several perspectives, including those of CPD, health systems, knowledge translation and sex and gender

Integrated immunovirological profiling validates plasma SARS-CoV-2 RNA as an early predictor of COVID-19 mortality.

peer reviewedDespite advances in COVID-19 management, identifying patients evolving toward death remains challenging. To identify early predictors of mortality within 60 days of symptom onset (DSO), we performed immunovirological assessments on plasma from 279 individuals. On samples collected at DSO11 in a discovery cohort, high severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral RNA (vRNA), low receptor binding domain–specific immunoglobulin G and antibody-dependent cellular cytotoxicity, and elevated cytokines and tissue injury markers were strongly associated with mortality, including in patients on mechanical ventilation. A three-variable model of vRNA, with predefined adjustment by age and sex, robustly identified patients with fatal outcome (adjusted hazard ratio for log-transformed vRNA = 3.5). This model remained robust in independent validation and confirmation cohorts. Since plasma vRNA’s predictive accuracy was maintained at earlier time points, its quantitation can help us understand disease heterogeneity and identify patients who may benefit from new therapies