319 research outputs found

    Photoacoustics Modelling using Amplitude Mode Expansion Method in a Multiscale T-cell Resonator

    Full text link
    The photoacoustic (PA) effect consisting of the generation of an acoustic signal based on the absorption of light has already demonstrated its potential for various spectroscopic applications for both gaseous and solid samples. The signal produced during photoacoustic spectroscopy (PAS) measurement is, however, usually weak and needs to be amplified. This is achieved by using a photoacoustic cell resonator where acoustic resonances are utilized to significantly boost the signal. Therefore, a PA resonator has a significant role in PAS measurement set-ups. When designing or optimizing a new PA resonator, numerical methods are generally used to simulate the photoacoustic signal generation. In this paper, the amplitude mode expansion (AME) method is presented as a quick and accurate simulation tool. The method is used to simulate the photoacoustic signal in a multi-scale T-cell resonator over a wide frequency range. The AME method is based on eigenmode expansion and introduction of losses by quality factors. The AME simulation results are compared and analyzed against the results from the viscothermal method. Reasonably good agreement is obtained between the two methods. However, small frequency shifts in the resonances of the AME method are noted. The shifts are attributed to the location of the dominant mode within the T-cell. The viscothermal method is considered the most accurate method for simulating the photoacoustic signal in small resonators. However, it is computationally very demanding. The AME method provides a much faster simulation alternative. This is particularly useful in the design and optimization of photoacoustic resonators where numerical methods are preferred over experimental measurements due to their speed and low cost.Comment: Comsol Conference 201

    E-Government Implementation in Oman: A Comparative Study of Three Public Agencies

    Get PDF
    The concept of electronic government has established as an effective mechanism for increasing government productivity and efficiency and a key enabler of citizen-centric services. In Gulf countries, public sector transformation efforts are focused towards increasing accessibility, availability, competitive advantage and enhancing services in civil administration. The Sultanate of Oman is one such example of Gulf countries where large investments have been made since 2003 to implement electronic services in the public sector. Using a qualitative research approach, this research attempts to answer the question why the progress of e-government has been slow in some governmental ministries, whereas other ministries have implemented e-government in a successful manner. The paper investigates the improvements that have been made to facilitate these electronic services in three public ministries and their resulting impact within the organisations. The results of the empirical study reveal some of the generic issues faced by the Omani government in implementing e-services and how other specific challenges faced by the individual ministries such as top management support, integration and IT staff skills and capabilities are impeding e-government in the Omani public sector

    The Legal Nature of the Concessions and Investments Contracts Concluded by States in accordance with B.O.T. System

    Get PDF
    Different States conclude contracts for running public utilities or for investing public money. These contracts are known as concession contracts. The introduction of modern legalmethods: the BOT and the BOOT have complicated the arguments as to the legalnature of these contracts: are they classified under administrative contract or are they categorized as private law contracts? The main purpose of this research is to analyze the legalnature of these contracts. The research concludes and affirms administrative nature of the concession contracts concluded by States in accordance with the BOT system. These contracts require: A- Administrative authorizations b- Their procedures are lengthy and subject to administrative law rules. c- The subjects of the contracts are public utilities or public services and public constructions. d- They include unfamiliar and unknown conditions in private contracts. e- Governments entering into these contracts as public power

    Factors Influencing eGovernment Progress in Oman: An Employee\u27s Perspective

    Get PDF
    While most early e-government efforts were concentrated on developed countries, in the recent past, it has also become popular in many developing countries. Most notably are the Middle Eastern countries that have continued to invest significantly into e-government initiatives in the last five years. However, compared to the West, the progress of e-government implementation and diffusion has been laggard in the Middle East region. The Sultanate of Oman is one such example, where, although large investments have been made since 2003 to facilitate the implementation of electronic services in the public sector, only limited progress has been made in terms of realising fully functional e-government. The aim of this paper is to identify the factors that are currently influencing the development and implementation of e-government in Oman using a quantitative survey-based empirical study in three key public service agencies. The research identified thirteen different factors that were influencing the progress of the national e-government project, e-Oman, from the viewpoint of government employees. The most salient of these factors were the Omani IT workforce capability and the citizens’ trust and confidence in using e-services

    Reappraisal of the dimensions of the diaphragma sellae

    Get PDF
    Morphometric dimensions of diaghragma sellae influence the extent of instrumentation and tumour exposure in the hypophyseal fossa, and the degree of compression of visual fibres from an expanding pituitary tumor. The dimensions show inter-population variations but data from Africans is scarcely available in literature. We aimed to investigate the morphometric dimensions of diaghragma sellae in an adult Kenyan population. One hundred and forty wet open crania (96 males, 44 females) obtained from the Department of Human Anatomy, University of Nairobi were studied. The shape of diaphragma sellae was classified as round or elliptical (elliptical was further classified as coronal elliptical or sagittal elliptical). The sagittal and coronal dimensions of the sellae were also determined. The diaphragma sellae was round in 60% of cases, coronal elliptical in 34% and sagittal elliptical in 6%. It was significantly wider in females than males (10.26+2.61mm vs 8.37+1.82mm respectively), p= <0.05. It was also wider in the coronal than sagittal dimension (20.01+2.00mm vs 18.45+2.97mm) and this difference was statistically significant. The significantly wider diaphragma sellae in females may provide better tumor exposure during surgery and may protect the visual fibres from a suprasellar extension of an expanding pituitary tumour. On the other hand, the larger coronal than sagittal sellae dimension should be considered during instrumentation in the hypophyseal fossa to avoid inadvertent neurovascular injury.Key words: Diaphragma sellae, Morphology, Morphometr

    Variant anatomy of sciatic nerve in a black Kenyan population

    Get PDF
    Knowledge of variant anatomy of the sciatic nerve is important in avoiding inadvertent injury during operations in the gluteal region and interpreting nondiscogenic sciatica. This variant anatomy may cause piriformis syndrome and failure of sciatic nerve block. The variations differ between populations but data from Africans is scarce. This study, therefore, investigated variations of sciatic nerve in a black Kenyan population. One hundred and sixty-four sciatic nerves from 82 cadavers of black Kenyans were exposed by dissection at the Department of Human Anatomy, University of Nairobi, Kenya. The level of bifurcation, relationship to piriformis, and topographic relations between the branches were studied. The results were analysed by SPSS version 16.0 and are presented by macrographs. In 33 (20.1%) cases division occurred in the pelvis, while in 131 (79.9%) it occurred outside the pelvis. A single trunk sciatic nerve exited below the piriformis muscle in 131 (79.9%) cases. In cases of pelvic division, the tibial nerve was always infrapiriformic, while the common peroneal nerve passed below piriformis in 16 (9.8%) cases, pierced the piriformis in 13 (7.9%), and passed above it in 4 (2.4%). For those in which division was extrapelvic, 110 (67.1%) were in the popliteal fossa, 17 (10.4%) in the middle third of the thigh, and 4 (2.4%) in the gluteal region. Where the division was pelvic, in 19 (11.6%) cases they continued separately, in 8 (4.9%) the two nerves reunited, and in 6 (3.7%) they were connected by a communicating nerve. The sciatic nerve in the Kenyan population varies from the classical description in over 30% of cases, with many high divisions, low incidence of piriformic course of common peroneal nerve, reunion, and unusual connection between common peroneal and tibial nerves. These variations may complicate surgery and interpretation of sciatic neuropathy. Preoperative nerve imaging and extra operative diligence in the gluteal region and the back of the thigh are recommended. (Folia Morphol 2011; 70, 3: 175–179

    Age changes in the structure of human Atrioventricular annuli

    Get PDF
    Atrioventricular annuli are important in hemodynamic stability and support to tricuspid and mitral valves. Anatomical features of the annuli such as circumference, organization of connective tissue fibers, myocardium and cellularity may predispose to annular insufficiency and valvular incompetence. These pathologies increase with age and are more common in females, although the anatomical basis for this disparity remains unclear. This study therefore aimed to investigate age-related changes in the structure of human atrioventricular annuli. One hundred and one hearts (48males, 53 females) from subjects (15 to 60 years) were studied in three age groups (≀ 20 yrs, 21-39 yrs and 40-60 yrs). Annular circumferences were measured and corrected for heart weight. Routine histology was carried out on 21 hearts. Differences in annular circumference between the age groups were determined using one-way ANOVA while gender differences were determined using independent Students’t-test. Overall, females had significantly larger annular circumference than males after correcting for heart weight (p ≀0.05). The annular circumference generally increased with age however there was a significant increase in the 21-39 year age group (p ≀0.05). Microscopically, myocardium was consistently present in males but absent in females except in one specimen. The collagen fiber density increased with age in both gender as the fibers became more irregular. The annular cellularity, elasticity and myocardial content also declined with increasing age. The significantly wider annular circumference in the 21-39 year age group is clinically important as wider circumference is associated with decreased heart valve co-aptation and valvular incompetence. This may suggest an earlier predisposition to this pathology in the study population. The age-related decrease in annular cellularity, elasticity and myocardial content may explain the higher incidence of valvular incompetence with increasing age.Key words: Atrioventricular annuli; Age changes; Valve incompetence

    Challenges Associated with Tyrosine Kinase Inhibitor Therapy for Metastatic Thyroid Cancer

    Get PDF
    Tyrosine kinase inhibitors (TKIs) which target angiogenesis are promising treatments for patients with metastatic medullary and differentiated thyroid cancers. Sorafenib, sunitinib, and pazopanib are commercially available drugs which have been studied in these diseases. Vandetanib is the first drug approved in the United States for treatment of medullary thyroid cancer. These TKIs are used as chronic therapies, and therefore it is imperative to understand the adverse event profile in order to avoid excessive toxicity and maintain patients on therapy as long as it proves beneficial. Here we review common toxicities, management of these, and other challenging situations that arise when using TKIs in patients with thyroid cancer
    • 

    corecore