280 research outputs found
A pre-design sensitivity analysis tool for consideration of full electrical aircraft propulsion electrical power system architectures
Turbo-electric distributed power (TeDP) systems proposed for hybrid wing body (HWB) N3-X aircraft are complex, superconducting electrical networks, which must be developed to meet challenging weight, efficiency and propulsor power requirements. An integrated system sensitivity analysis tool is presented, which can be used to support rapid appraisal studies of architectures, protection systems and redundancy requirements for TeDP systems. The use of this tool can help direct future research on TeDP systems towards the key challenges relevant to meeting the stringent weight and efficiency targets set out for N+3 aircraft concepts
Vector Bundle Moduli and Small Instanton Transitions
We give the general presciption for calculating the moduli of irreducible,
stable SU(n) holomorphic vector bundles with positive spectral covers over
elliptically fibered Calabi-Yau threefolds. Explicit results are presented for
Hirzebruch base surfaces B=F_r. The transition moduli that are produced by
chirality changing small instanton phase transitions are defined and
specifically enumerated. The origin of these moduli, as the deformations of the
spectral cover restricted to the ``lift'' of the horizontal curve of the
M5-brane, is discussed. We present an alternative description of the transition
moduli as the sections of rank n holomorphic vector bundles over the M5-brane
curve and give explicit examples. Vector bundle moduli appear as gauge singlet
scalar fields in the effective low-energy actions of heterotic superstrings and
heterotic M-theory.Comment: 52 pages, LATEX, corrected typo
Vector Bundle Moduli Superpotentials in Heterotic Superstrings and M-Theory
The non-perturbative superpotential generated by a heterotic superstring
wrapped once around a genus-zero holomorphic curve is proportional to the
Pfaffian involving the determinant of a Dirac operator on this curve. We show
that the space of zero modes of this Dirac operator is the kernel of a linear
mapping that is dependent on the associated vector bundle moduli. By explicitly
computing the determinant of this map, one can deduce whether or not the
dimension of the space of zero modes vanishes. It is shown that this
information is sufficient to completely determine the Pfaffian and, hence, the
non-perturbative superpotential as explicit holomorphic functions of the vector
bundle moduli. This method is illustrated by a number of non-trivial examples.Comment: 81 pages, LaTeX, corrected typo
Global Fluctuation Spectra in Big Crunch/Big Bang String Vacua
We study Big Crunch/Big Bang cosmologies that correspond to exact world-sheet
superconformal field theories of type II strings. The string theory spacetime
contains a Big Crunch and a Big Bang cosmology, as well as additional
``whisker'' asymptotic and intermediate regions. Within the context of free
string theory, we compute, unambiguously, the scalar fluctuation spectrum in
all regions of spacetime. Generically, the Big Crunch fluctuation spectrum is
altered while passing through the bounce singularity. The change in the
spectrum is characterized by a function , which is momentum and
time-dependent. We compute explicitly and demonstrate that it arises
from the whisker regions. The whiskers are also shown to lead to
``entanglement'' entropy in the Big Bang region. Finally, in the Milne orbifold
limit of our superconformal vacua, we show that and, hence, the
fluctuation spectrum is unaltered by the Big Crunch/Big Bang singularity. We
comment on, but do not attempt to resolve, subtleties related to gravitational
backreaction and light winding modes when interactions are taken into account.Comment: 68 pages, 1 figure; typos correcte
Defining the essence of innovation how important terms in promoting of transformation processes in Ukraine
Feature hierarchies are essential to many visual object recognition systems and are well motivated by observations in biological systems. The present paper proposes an algorithm to incrementally compute feature hierarchies. The features are represented as estimated densities, using a variant of local soft histograms. The kernel functions used for this estimation in conjunction with their unitary extension establish a tight frame and results from framelet theory apply. Traversing the feature hierarchy requires resampling of the spatial and the feature bins. For the resampling, we derive a multi-resolution scheme for quadratic spline kernels and we derive an optimization algorithm for the upsampling. We complement the theoretic results by some illustrative experiments, consideration of convergence rate and computational efficiency.DIPLECSGARNICSELLII
Life path analysis: scaling indicates priming effects of social and habitat factors on dispersal distances
1. Movements of many animals along a life-path can be separated into repetitive ones within home ranges and transitions between home ranges. We sought relationships of social and environmental factors with initiation and distance of transition movements in 114 buzzards Buteo buteo that were marked as nestlings with long-life radio tags.
2. Ex-natal dispersal movements of 51 buzzards in autumn were longer than for 30 later in their first year and than 35 extra-natal movements between home ranges after leaving nest areas. In the second and third springs, distances moved from winter focal points by birds that paired were the same or less than for unpaired birds. No post-nuptial movement exceeded 2 km.
3. Initiation of early ex-natal dispersal was enhanced by presence of many sibs, but also by lack of worm-rich loam soils. Distances travelled were greatest for birds from small broods and with relatively little short grass-feeding habitat near the nest. Later movements were generally enhanced by the absence of loam soils and short grassland, especially with abundance of other buzzards and probable poor feeding habitats (heathland, long grass).
4. Buzzards tended to persist in their first autumn where arable land was abundant, but subsequently showed a strong tendency to move from this habitat.
5. Factors that acted most strongly in ½-km buffers round nests, or round subsequent focal points, usually promoted movement compared with factors acting at a larger scale. Strong relationships between movement distances and environmental characteristics in ½-km buffers, especially during early ex-natal dispersal, suggested that buzzards became primed by these factors to travel far.
6. Movements were also farthest for buzzards that had already moved far from their natal nests, perhaps reflecting genetic predisposition, long-term priming or poor habitat beyond the study area
Autologous haematopoietic stem cell transplantation as a first-line disease-modifying therapy in patients with ‘aggressive’ multiple sclerosis
Background:
Autologous haematopoietic stem cell transplantation (AHSCT) is an effective treatment for patients with multiple sclerosis (MS) who have highly active disease, despite the use of standard disease-modifying therapies (DMTs). However, the optimal time for offering AHSCT to patients with ‘aggressive’ MS is yet to be established.
Objectives:
The objective was to explore the safety and efficacy of AHSCT as a first-line DMT in patients with ‘aggressive’ MS.
Methods:
All patients with ‘aggressive’ MS who received AHSCT as a first-line DMT in five European and North American centres were retrospectively evaluated.
Results:
Twenty patients were identified. The median interval between diagnosis and AHSCT was 5 (1–20) months. All had multiple poor prognostic markers with a median pre-transplant Expanded Disability Status Scale (EDSS) score of 5.0 (1.5–9.5). After a median follow-up of 30 (12–118) months, the median EDSS score improved to 2.0 (0–6.5, p < 0.0001). No patient had further relapses. Three had residual magnetic resonance imaging (MRI) disease activities in the first 6 months post-transplant, but no further new or enhancing lesions were observed in subsequent scans.
Conclusion:
AHSCT is safe and effective as a first-line DMT in inducing rapid and sustained remission in patients with ‘aggressive’ MS
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