2,659 research outputs found

    Space station interior noise analysis program

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    Documentation is provided for a microcomputer program which was developed to evaluate the effect of the vibroacoustic environment on speech communication inside a space station. The program, entitled Space Station Interior Noise Analysis Program (SSINAP), combines a Statistical Energy Analysis (SEA) prediction of sound and vibration levels within the space station with a speech intelligibility model based on the Modulation Transfer Function and the Speech Transmission Index (MTF/STI). The SEA model provides an effective analysis tool for predicting the acoustic environment based on proposed space station design. The MTF/STI model provides a method for evaluating speech communication in the relatively reverberant and potentially noisy environments that are likely to occur in space stations. The combinations of these two models provides a powerful analysis tool for optimizing the acoustic design of space stations from the point of view of speech communications. The mathematical algorithms used in SSINAP are presented to implement the SEA and MTF/STI models. An appendix provides an explanation of the operation of the program along with details of the program structure and code

    Olfactory variation in mouse husbandry and its implications for refinement and standardisation: UK survey of non-animal scents

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    With their highly sensitive olfactory system, the behaviour and physiology of mice are not only influenced by the scents of conspecifics and other species, but also by many other chemicals in the environment. The constraints of laboratory housing limit a mouse’s capacity to avoid aversive odours that could be present in the environment. Potentially odorous items routinely used for husbandry procedures, such as sanitizing products and gloves, could be perceived by mice as aversive or attractive, and affect their behaviour, physiology and experimental results. A survey was sent to research institutions in the UK to enquire about husbandry practices that could impact on the olfactory environment of the mouse. Responses were obtained from 80 individuals working in 51 institutions. Husbandry practices varied considerably. Seventy percent of respondents reported always wearing gloves for handling mice, with nitrile being the most common glove material (94%) followed by latex (23%) and vinyl (14%). Over six different products were listed for cleaning surfaces, floors, anaesthesia and euthanasia chambers and behavioural apparatus. In all cases Trigene™ (now called Anistel™) was the most common cleaning product used (43, 41, 40 and 49%, respectively). Depending on the attribute considered, between 7 and 19% of respondents thought that cleaning products definitely, or were likely to, have strong effects on standardization, mouse health, physiology or behaviour. Understanding whether and how these odours affect mouse welfare will help to refine mouse husbandry and experimental procedures through practical recommendations, to improve the quality of life of laboratory animals and the experimental data obtained

    Magnetization switching and domain-wall propagation behavior in edge-modulated ferromagnetic nanowire structures

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    The magnetization reversal processes in ferromagnetic nanowires with sinusoidally modulated edges were investigated as a function of modulation amplitude and wavelength. The reversal processes were studied in two regimes: nucleation controlled reversal and magnetization reversal mediated by domain-wall propagation. In the latter case, domain walls were introduced using both nucleation-pad structures and local pulsed-field injection techniques. The reversal behavior shows that competing effects govern the switching fields in these structures, giving a minimum as a function of modulation wavelength, showing promising results for improved control of domain-wall propagation behavior. The experimental results were interpreted with detailed micromagnetic simulations and an analytical model, based on the demagnetization effects of the modulation upon the spin structure of the wire. The analysis highlights consistent trends in the reversal behavior resulting from modulation, and, significantly, the switching behavior is found to be scalable in relation to the amplitude and wavelength

    Inspiring Music for All: next steps in innovation, improvement and integration

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    The report, funded by the Paul Hamlyn Foundation, provides an overview of schools-based music education in England. It represents the outcomes of research undertaken in January and February 2014 which included detailed literature reviews, personal interviews with thirty-five specialists involved in leading various organisations responsible for different aspects of music education, focus group discussions and an on-line survey of the music education workforce that generated 515 responses. The findings suggest that the place and status of music in schools vary widely across the country. The best music in schools is significantly more inclusive, more musically diverse and better quality that it was a decade ago. However, the quality and reach of schools-based music education is still unacceptably variable and inconsistent at both primary and secondary levels. Detailed findings and recommendations are included in the report

    Appearance-based localization for mobile robots using digital zoom and visual compass

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    This paper describes a localization system for mobile robots moving in dynamic indoor environments, which uses probabilistic integration of visual appearance and odometry information. The approach is based on a novel image matching algorithm for appearance-based place recognition that integrates digital zooming, to extend the area of application, and a visual compass. Ambiguous information used for recognizing places is resolved with multiple hypothesis tracking and a selection procedure inspired by Markov localization. This enables the system to deal with perceptual aliasing or absence of reliable sensor data. It has been implemented on a robot operating in an office scenario and the robustness of the approach demonstrated experimentally

    A Radio Polarimetric Study of the Galactic Center Threads

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    Multi-frequency, polarimetric VLA observations of the non-thermal filaments (NTF's), G0.08+0.15, and G359.96+0.09, also known as the Northern and Southern Threads are presented at 20, 6, 3.6 and 2 cm, with high enough spatial resolution to be resolved for the first time at 6 and 3.6 cm. The 20 cm image reveals a wealth of new detail in the radio sources lying within the inner 60 pc of the Galaxy. The Southern Thread has a prominent split along its length, similar to splitting at the ends of previously studied NTF's. With resolutions as fine as 2'', the 3.6 and 6 cm images reveal a high degree of continuity and little substructure internal to the filament. The spectral index of the Northern Thread has been determined over a broad range of frequencies. Its flux density falls with frequency, alpha=-0.5 between 90 and 6 cm, and becomes much steeper (alpha=-2.0) between 6 and 2 cm. The spectral index does not vary significantly along the length of the Northern Thread, which implies either that the diffusion timescale for the emitting electrons is less than their synchrotron lifetime, or that the emitting electrons are reaccelerated continuously at multiple positions along the filament. Because of the lack of spectral index variation, we have not located the source of relativistic electrons. Polarization observations at 6 and 3.6 cm confirm the non-thermal nature of the emission from the Northern Thread. The fractional polarization in the Northern Thread reaches 70% in some regions, although the polarized emission is patchy. Large rotation measures (RM > 2000 rad/m2) have been observed with irregular variations across the filament.The intrinsic magnetic field in the Northern Thread is predominantly aligned along its long axis.Comment: 19 pages, incl. 24 figs; to appear in the Astrophysical Journa

    Three decades of the Human Genome Organization.

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    The Human Genome Organization (HUGO) was initially established in 1988 to help integrate international scientific genomic activity and to accelerate the diffusion of knowledge from the efforts of the human genome project. Its founding President was Victor McKusick. During the late 1980s and 1990s, HUGO organized lively gene mapping meetings to accurately place genes on the genome as chromosomes were being sequenced. With the completion of the Human Genome Project, HUGO went through some transitions and self-reflection. In 2020, HUGO (which hosts a large annual scientific meeting and comprises the renowned HUGO Gene Nomenclature Committee [HGNC], responsible for naming genes, and an outstanding Ethics Committee) was merged with the Human Genome Variation Society (HGVS; which defines the correct nomenclature for variation description) and the Human Variome Project (HVP; championed by the late Richard Cotton) into a single organization that is committed to assembling human genomic variation from all over the world. This consolidated effort, under a new Executive Board and seven focused committees, will facilitate efficient and effective communication and action to bring the benefits of increasing knowledge of genome diversity and biology to people all over the world
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