29 research outputs found
Users manual: Dynamics of two bodies connected by an elastic tether, six degrees of freedom forebody and five degrees of freedom decelerator
The equations of motion and a computer program for the dynamics of a six degree of freedom body joined to a five degree of freedom body by a quasilinear elastic tether are presented. The forebody is assumed to be a completely general rigid body with six degrees of freedom; the decelerator is also assumed to be rigid, but with only five degrees of freedom (symmetric about its longitudinal axis). The tether is represented by a spring and dashpot in parallel, where the spring constant is a function of tether elongation. Lagrange's equation is used to derive the equations of motion with the Lagrange multiplier technique used to express the constraint provided by the tether. A computer program is included which provides a time history of the dynamics of both bodies and the tension in the tether
Computer program for the load and trajectory analysis of two DOF bodies connected by an elastic tether: Users manual
The derivation of the differential equations of motion of a 3 Degrees of Freedom body joined to a 3 Degrees of Freedom body by an elastic tether. The tether is represented by a spring and dashpot in parallel. A computer program which integrates the equations of motion is also described. Although the derivation of the equations of motions are for a general system, the computer program is written for defining loads in large boosters recovered by parachutes
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Evolutionary genomic analyses of canine E. coli infections identify a relic capsular locus associated with resistance to multiple classes of antimicrobials.
UNLABELLED: Infections caused by antimicrobial-resistant Escherichia coli are the leading cause of death attributed to antimicrobial resistance (AMR) worldwide, and the known AMR mechanisms involve a range of functional proteins. Here, we employed a pan-genome wide association study (GWAS) approach on over 1,000 E. coli isolates from sick dogs collected across the US and Canada and identified a strong statistical association (empirical P < 0.01) of AMR, involving a range of antibiotics to a group 1 capsular (CPS) gene cluster. This cluster included genes under relaxed selection pressure, had several loci missing, and had pseudogenes for other key loci. Furthermore, this cluster is widespread in E. coli and Klebsiella clinical isolates across multiple host species. Earlier studies demonstrated that the octameric CPS polysaccharide export protein Wza can transmit macrolide antibiotics into the E. coli periplasm. We suggest that the CPS in question, and its highly divergent Wza, functions as an antibiotic trap, preventing antimicrobial penetration. We also highlight the high diversity of lineages circulating in dogs across all regions studied, the overlap with human lineages, and regional prevalence of resistance to multiple antimicrobial classes. IMPORTANCE: Much of the human genomic epidemiology data available for E. coli mechanism discovery studies has been heavily biased toward shiga-toxin producing strains from humans and livestock. E. coli occupies many niches and produces a wide variety of other significant pathotypes, including some implicated in chronic disease. We hypothesized that since dogs tend to share similar strains with their owners and are treated with similar antibiotics, their pathogenic isolates will harbor unexplored AMR mechanisms of importance to humans as well as animals. By comparing over 1,000 genomes with in vitro antimicrobial susceptibility data from sick dogs across the US and Canada, we identified a strong multidrug resistance association with an operon that appears to have once conferred a type 1 capsule production system
A critical geopolitics of observant practice at British military airshows
ArticleCopyright © 2015 The Authors. Transactions of the Institute of British Geographers published by John Wiley & Sons Ltd on behalf of Royal Geographical Society (with The Institute of British Geographers)This paper demonstrates how visual cultures of militarism take shape as part of a ‘thick’ geopolitics of being-in-place. It draws on historical accounts of, and empirical observations at, British military airshows, which it interprets via the concept of ‘observant practice’. The paper argues that the imaginative and rhetorical force of military spectacle and popular militarism are tied to its markedly enclavic spatiality, i.e. to seeing and doing in-place. By taking seriously the spatial and sensory experience of British airshows, the paper extends recent work in critical geopolitics that questions the spatialised politics of experience, and brings them into dialogue with cultural geographies of tourism. It provides a brief history of the spectacular origins of aviation and of the use of airshows to the practice of statecraft, and demonstrates how airshows are an important element in the cultural phenomenon of militarisation. The paper takes forward debates around ‘the vision thing’ in critical geopolitics by illustrating why the notion of observant practice should not be dissociated from consideration of the spaces in and through which militaries become the object of visual curiosity. It expands, therefore, the potential of observant practice as a critique of popular military cultures.ESR
"Queerowanie” Ameryki: wizja radykalnej przygodności Joy Harjo
Joan Burbick proponuje lekturę Jay Harjo z podwójnej perspektywy: queerowej i post-kolonialnej. Normatywny język społecznego scalenia zostaje zakwestionowany i przeformułowany przy pomocy kategorii szczególnych dla amerykańskich Indian, takich jak berdache. Wizja świata przedstawiona w poezji Harjo opiera się na radykalnej przygodności i pozornie „uduchowionej” kategorii przeniesienia.Joan Burbick reads Jay Harjo from a queering as well as post-colonial perspective, analyzing the way in which normative discourses of social cohesion are questioned and re-formulated from the vantage point of Native American categories such as the berdache. Harjo's vision promotes radical contingency and a seemingly spiritual notion of transference
sj-pdf-1-vdi-10.1177_10406387241241042 – Supplemental material for Genomic characterization of antimicrobial resistance in 61 aquatic bacterial isolates
Supplemental material, sj-pdf-1-vdi-10.1177_10406387241241042 for Genomic characterization of antimicrobial resistance in 61 aquatic bacterial isolates by Chrissy D. Eckstrand, Brandi K. Torrevillas, Rebecca M. Wolking, Marla Francis, Laura B. Goodman, Olgica Ceric, Trevor L. Alexander, Kevin R. Snekvik and Claire R. Burbick in Journal of Veterinary Diagnostic Investigation</p