12 research outputs found
The concept of leukaemic stem cells in acute myeloid leukaemia 25Â years on: hitting a moving target
No full textRelationship between the in vitro sensitivity to cytosine arabinoside of blast progenitors and the outcome of treatment in acute myeloblastic leukaemia patients
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In vitro culture of clonogenic leukaemic cells in acute myeloid leukaemia: growth pattern and drug sensitivity
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Role of laboratory chemosensitivity testing in the selection of cancer chemotherapy for individual patients.
No full textBrain tumour stem cells: the undercurrents of human brain cancer and their relationship to neural stem cells
No full textConceptual and technical advances in neural stem cell biology are being applied to the study of human brain tumours. These studies suggest that human brain tumours are organized as a hierarchy and are maintained by a small number of tumour cells that have stem cell properties. Most of the bulk population of human brain tumours comprise cells that have lost the ability to initiate and maintain tumour growth. Although the cell of origin for human brain tumours is uncertain, recent evidence points towards the brain's known proliferative zones. The identification of brain tumour stem cells has important implications for understanding brain tumour biology and these cells may be critical cellular targets for curative therapy
Subpopulations of primary adult murine epidermal basal cells sedimented on density gradients
No full textImmunohistochemical markers of cellular proliferation: achievements, problems and prospects
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