Информативность нейрофизиологических и нейровизуализационных показателей в диагностике умеренных когнитивных нарушений при дисциркуляторной энцефалопатии

144 patients with dyscirculatory encephalopathy (DE) I and 386 patients with DE II were investigated. The control groups included 76 subjects with no cerebrovascular disease. From neurologycal and neuropsychologycal tests and multyspiral computer tomography and electroencephalography it was exposed that vascular mild cognitive impairments have dysfunction from neuroregulation. Neurophisiological and neurovisualisation exponents have diagnostic information from vascular mild cognitive impairments.С целью уточнить информативность нейрофизиологических и нейровизуализационных показателей в диагностике умеренных когнитивных нарушений при дисциркуляторной энцефалопатии (ДЭ) обследовано 144 больных ДЭ I стадии, 386 больных ДЭ II стадии. Контрольную группу составили 76 человек, не страдающих сердечно-сосудистыми заболеваниями. Проведены клиническое неврологическое и нейропсихологическое исследования, электроэнцефалография, мультиспиральная компьютерная томография. Уточнена роль нейрорегуляторных нарушений в формировании когнитивных расстройств при ДЭ. Доказана диагностическая ценность нейрофизиологических показателей и нейровизуализационных характеристик у больных с сосудистыми когнитивными нарушениями

ON THE TERMINOLOGY OF SPONDYLOARTHRITIS

By the end of the first decade of the 21st century, spondyloarthritis studies have accumulated a certain number of terms that are obsolete, but used by physicians in their everyday speech, on the one hand, and a great variety of different definitions, on the other hand. In January 2014, the first organizational meeting of the Expert Group on Spondyloarthritis, Association of Rheumatologists of Russia, decided that its primary task should be to order the terminology used in this area. The authors primarily collected the terms, which had been already used in medical vocabulary, and then divided them into two categories: obsolete definitions and terms to be finalized and unified. This publication gives guidelines for using the medical terms relevant to spondyloarthritis and separately discusses how to correctly write the term sacroiliitis

Methodology and Historical Perspective of a Hall Thruster Efficiency Analysis

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/77214/1/AIAA-38092-814.pd

Cause of Death and Predictors of All-Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation : Data From ROCKET AF

M. Kaste on työryhmän ROCKET AF Steering Comm jäsen.Background-Atrial fibrillation is associated with higher mortality. Identification of causes of death and contemporary risk factors for all-cause mortality may guide interventions. Methods and Results-In the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) study, patients with nonvalvular atrial fibrillation were randomized to rivaroxaban or dose-adjusted warfarin. Cox proportional hazards regression with backward elimination identified factors at randomization that were independently associated with all-cause mortality in the 14 171 participants in the intention-to-treat population. The median age was 73 years, and the mean CHADS(2) score was 3.5. Over 1.9 years of median follow-up, 1214 (8.6%) patients died. Kaplan-Meier mortality rates were 4.2% at 1 year and 8.9% at 2 years. The majority of classified deaths (1081) were cardiovascular (72%), whereas only 6% were nonhemorrhagic stroke or systemic embolism. No significant difference in all-cause mortality was observed between the rivaroxaban and warfarin arms (P=0.15). Heart failure (hazard ratio 1.51, 95% CI 1.33-1.70, P= 75 years (hazard ratio 1.69, 95% CI 1.51-1.90, P Conclusions-In a large population of patients anticoagulated for nonvalvular atrial fibrillation, approximate to 7 in 10 deaths were cardiovascular, whereasPeer reviewe

Diagnostic information of neurophisiological and neurovisualisation exponents from vascular mild cognitive impairments

144 patients with dyscirculatory encephalopathy (DE) I and 386 patients with DE II were investigated. The control groups included 76 subjects with no cerebrovascular disease. From neurologycal and neuropsychologycal tests and multyspiral computer tomography and electroencephalography it was exposed that vascular mild cognitive impairments have dysfunction from neuroregulation. Neurophisiological and neurovisualisation exponents have diagnostic information from vascular mild cognitive impairments

RED BLOOD VALUES CHANGES IN CARDIOVASCULAR PATIENTS — EPIDEMIOLOGY, PROGNOSIS AND TREATMENT APPROACHES

The review highlights a significance of anemic syndrome in cardiovascular patients, which is certainly negatively related to life quality and prognosis of patients. The main causes for its development are discussed, of those the main are hemodilution, inflammatory cytokines, iron deficiency. Also anemia correction is discussed and the main trials of this field are mentioned. The U-shaped relation is discussed for hemoglobin concentration and cardiovascular morbidity and mortality which reflect that higher levels of hemoglobin and hematocrit are associated with poorer outcome. There is lack of information on the prevalence and influence of hemoconcentration on prognosis in cardiological patients, as the data available is usually controversial. The conclusion is made that at the moment the problem of target hemoglobin and hematocrit levels definition for anemia treatment in cardiological patients, as also the data on the hemoconcentration influence of course and prognosis of cardiovascular diseases remains open

Characterization of bimetallic PdAg nanoparticle arrays by the diblock copolymer micelle approach

International audienc

TUMOR NECROSIS FACTOR-α INHIBITORS IN THE TREATMENT OF AXIAL SPONDYLOARTHRITIS, INCLUDING ANKYLOSING SPONDYLITIS

The paper provides guidelines for the use of tumor necrosis factor-α  (TNF-α) inhibitors in the treatment of patients with axial spondyloarthritis  (axSpA), including ankylosing spondylitis. It gives data on the efficacy of TNF-α inhibitors in patients with non-radiographic axSpA. By using international and Russian guidelines, the authors lay down indications for this therapy and criteria for evaluation of its efficiency and safety