A New Type of Supramolecular Fluid Based on H₂O-Alkylammonium/Phosphonium Solutions

Here we show that by adjusting the concentration of tetrabutyl ammonium and phosphonium salts in water (approximate to 1.5-2.0 m), hydrophobic solvation triggers the formation of a unique, highly incompressible supramolecular liquid, with a dynamic structure similar to clathrates, involving essentially all H2O molecules of the solvent. Despite the increasing local order, the thermal diffusivity, and compressibility of these supramolecular liquids is strongly decreased with respect to bulk water due to slower relaxation dynamics. The results presented in this paper open an avenue to design a new family of supramolecular fluids, stable under atmospheric conditions, which can find important technological applications in energy storage and conversion

Discordant MZ twins With Cleft Lip and Palate: a model for identifying genes in complex traits.

Monozygotic (MZ) twins may be discordant for complex traits due to differential environmental exposure in utero, epigenetic variability in imprinting, X chromosome inactivation, or stochastic effects. Occasionally MZ twins may be discordant for chromosomal and single gene disorders due to somatic mosaicism. For complex traits, which are due to the interactive effects of multiple genes and environmental factors, the affected twin of a discordant MZ pair offers the possibility for identifying somatic mutations in candidate genes. DNA sequencing of candidate genes in discordant MZ twins can identify those rare etiologic mutational events responsible for the different phenotypes since the confounding effects of common single nucleotide polymorphisms are eliminated, as DNA sequences should be identical in MZ pairs. In this report we describe the extensive DNA sequencing of 18 candidate genes in a sample of MZ and dizygotic (DZ) twins with nonsyndromic cleft lip with or without cleft palate. We were unable to identify any somatic differences in approximately 34 Kb of DNA sequenced in 13 MZ pairs, for a total of approximately 900 Kb of sequence comparisons, supporting the hypothesis that nonetiologic posttwinning mutations are rare. While no etiologic variants were identified in this study, sequence comparisons of discordant MZ twins can serve as a tool for identifying etiologic mutations in clefting and other complex traits

Southwest as the New Internal Migration Destination in Turkey

Antalya and Muğla provinces located in southwestern Turkey have emerged as new magnets for internal migration in the country. Socio-economic, demographic and labor market characteristics of immigrants coming to these two provinces from various regions are studied to uncover the reasons fueling their moves. This is accomplished through an analysis of descriptive statistics, and an analysis of a gravity model estimated. Differences and similarities between immigrants coming to these two provinces and those going to other migrant magnets, between immigrants and natives in Antalya and Muğla, and among immigrants coming to the two provinces from various origins are noted. What distinguishes Antalya and Muğla from other migrant-drawing provinces is that they attract some retirees and university students as well and their immigrants participating in the labor force are attracted mainly by jobs created in the sectors related to tourism, either directly or indirectly, rather than industry. Immigrants from different origins exhibit different characteristics and tend to specialize in different types of jobs. However, as other migrant flows, those directed at Antalya and Muğla are affected by distance adversely and by unemployment differential, past migration and population size at origin, favorably

The European Reference Genome Atlas: piloting a decentralised approach to equitable biodiversity genomics

A genomic database of all Earth’s eukaryotic species could contribute to many scientific discoveries; however, only a tiny fraction of species have genomic information available. In 2018, scientists across the world united under the Earth BioGenome Project (EBP), aiming to produce a database of high-quality reference genomes containing all ~1.5 million recognized eukaryotic species. As the European node of the EBP, the European Reference Genome Atlas (ERGA) sought to implement a new decentralised, equitable and inclusive model for producing reference genomes. For this, ERGA launched a Pilot Project establishing the first distributed reference genome production infrastructure and testing it on 98 eukaryotic species from 33 European countries. Here we outline the infrastructure and explore its effectiveness for scaling high-quality reference genome production, whilst considering equity and inclusion. The outcomes and lessons learned provide a solid foundation for ERGA while offering key learnings to other transnational, national genomic resource projects and the EBP.info:eu-repo/semantics/publishedVersio

Unveiling the Confidence of Criminology Practitioners: Delving on Research Knowledge and Attitude

This study aims to investigate the level of confidence among criminology practitioners in their research knowledge and attitudes towards research. By examining both aspects, the study seeks to understand how these factors influence overall confidence in engaging with and applying research findings. Furthermore, this descriptive study explores whether there is a significant difference between practitioners' confidence levels related to their research knowledge and their attitudes towards research. Understanding these dynamics is crucial for enhancing the integration of research into criminology practice, thereby improving the effectiveness of interventions and policies. The study utilized a descriptive design having 128 qualified respondents using purposive sampling that answered the self-made questionnaire. Result shows that among the practitioner, academicians have higher level of confidence in terms of research knowledge and attitude. There is a significant difference between the level of confidence relative to research knowledge and attitude. Likewise, the research knowledge of the criminology practitioners has positive relationship among the scope of practice. Hence, the findings suggest that in order to improve the research culture within the field of criminology, a professional development plan might be created to address and cater to all criminology practitioners within the discipline, with guidelines based on the scope of practice under RA 11131

Measuring Recidivism Rate: Its Predictive Variables and Antecedents

This study examined the recidivism rate at the Bureau of Jail Management and Penology – National Capital Region (BJMP-NCR), Philippines, from 2020 to 2022 based on predictive variables and antecedents of recidivism. The results revealed that young individuals; males; married; Person Deprived of Liberty (PDL) with drug cases, leading to death or intending to cause death, and acts involving fraud and deception; and those having shorter stays in prison tend to recidivate more. Likewise, the pattern of recidivism in the Metro Manila District Jail (MMDJ) from 2020 to 2022 was affected by the existence of the COVID-19 pandemic. In conclusion, both predictive variables and antecedents of recidivism show no significant association with the pattern of recidivism