99 research outputs found

    Letter to Sonora Dodd from W. J. Bryan, July 8, 1910

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    Letter to Sonora Dodd from W. J. Bryan, Editor and Proprietor of The Commoner. William Jennings Bryan is historically significant as a major American orator and politician during the late 19th and early 20th centuries. Notably, Bryan made three failed attempts for the presidency of the United States, and also served as the prosecutor for the famous Scopes Trial in 1926.https://digitalcommons.whitworth.edu/fathers-day-correspondence/1021/thumbnail.jp

    Letter From William Jennings Bryan to Frank Irving Cobb, March 13, 1913

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    The document is a copy of a typed letter from William Jennings Bryan, the Secretary of State, to the managing editor of the New York World newspaper, Frank Irving Cobb, regarding the New York World\u27s reference to a cancelled telegram the day prior and requesting that he not link the telegram to Huntington Wilson.https://digitalcommons.ursinus.edu/fmhw_other/1244/thumbnail.jp

    Letter From William Jennings Bryan to Woodrow Wilson, March 16, 1913

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    This document is a typed letter to Woodrow Wilson by William Jennings Bryan. Bryan brings to Wilson\u27s attention the conflict between Huntington-Wilson and Chandler Anderson and believes it fair to comply with Wilson\u27s request to not work with Anderson.https://digitalcommons.ursinus.edu/fmhw_other/1248/thumbnail.jp

    Letter From William Jennings Bryan to Francis Mairs Huntington-Wilson, March 16, 1913

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    This document is a typed letter from William Jennings Bryan to Francis Mairs Huntington-Wilson in response to a previous letter Wilson sent in discussing matters of the department structuring and Wilson\u27s friction when working with Chandler Anderson.https://digitalcommons.ursinus.edu/fmhw_other/1247/thumbnail.jp

    Telegram From William Jennings Bryan to Francis Mairs Huntington-Wilson, March 19, 1913

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    This document is a telegram from William Jennings Bryan to Francis Mairs Huntington-Wilson in which Bryan gives condolences over Wilson\u27s resignation from the State Department.https://digitalcommons.ursinus.edu/fmhw_other/1250/thumbnail.jp

    Representative Moakley with Representatives Charles Diggs and William Jennings Bryan Dorn, audio recording and transcript, 1974

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    This recording includes two interviews with members of Congress that were broadcast on WILD and WCOP as episodes of a radio show featuring Congressman Moakley in the 1970s. Moakley interviews Representative Charles Diggs, chairman of the House District Committee, about the governance of Washington, D.C., also known as the District of Columbia, including the proposed Home Rule Bill which would change D.C.\u27s level of representation at the federal level and aspects of its local governance. The second interview is a discussion with William Jennings Bryan Dorn, chairman of the House Veterans’ Services Committee about benefits for veterans and legislation such as the Veterans Health Care Expansion Act of 1973.https://dc.suffolk.edu/moakley-av/1017/thumbnail.jp

    Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

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    BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

    Incorporating conceptual site models into national-scale environmental risk assessments for legacy waste in the coastal zone

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    Solid wastes deposited in the coastal zone that date from an era of lax environmental regulations continue to pose significant challenges for regulators and coastal managers worldwide. The increasing risk of contaminant release from these legacy disposal sites, due to a range of factors including rising sea levels, associated saline intrusion, and greater hydrological extremes, have been highlighted by many researchers. Given this widespread challenge, and the often-limited remedial funds available, there is a pressing need for the development of new advanced site prioritization protocols to limit potential pollution risks to sensitive ecological or human receptors. This paper presents a multi-criteria decision analysis that integrates the principles of Conceptual Site Models (Source-Pathway-Receptor) at a national scale in England and Wales to identify legacy waste sites where occurrence of pollutant linkages are most likely. A suite of spatial data has been integrated in order to score potential risks associated with waste type (Source), likelihood of pollutant release relating to current and future flood and erosion climate projections, alongside current management infrastructure (Pathway), and proximity to sensitive ecological features or proxies of human use in coastal areas (Receptors). Of the 30,281 legacy waste deposits identified in England and Wales, 3,219 were located within the coastal zone, with coastal areas containing a density of legacy wastes (by area) 10.5 times higher than inland areas. Of these, 669 were identified as priority sites in locations without existing coastal defences or flood management infrastructure, with 2550 sites identified in protected areas where contaminant transfer risks could still be apparent. The majority (63%) of the priority sites have either undefined source terms, or are classified as mixed wastes. Mining and industrial wastes were also notable waste categories, and displayed strong regional distributions in the former mining areas of north-east and south-west of England, south Wales, and post-industrial estuaries. The large-scale screening process presented here could be used by environmental managers as a foundation to direct more high-resolution site assessment and remedial work at priority sites, and can be used as a tool by governments for directing funding to problematic sites

    Procalcitonin Is Not a Reliable Biomarker of Bacterial Coinfection in People With Coronavirus Disease 2019 Undergoing Microbiological Investigation at the Time of Hospital Admission

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    Abstract Admission procalcitonin measurements and microbiology results were available for 1040 hospitalized adults with coronavirus disease 2019 (from 48 902 included in the International Severe Acute Respiratory and Emerging Infections Consortium World Health Organization Clinical Characterisation Protocol UK study). Although procalcitonin was higher in bacterial coinfection, this was neither clinically significant (median [IQR], 0.33 [0.11–1.70] ng/mL vs 0.24 [0.10–0.90] ng/mL) nor diagnostically useful (area under the receiver operating characteristic curve, 0.56 [95% confidence interval, .51–.60]).</jats:p
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