Intelligent systems for the molecular biologist

This tutorial was one of eight tutorials selected to be presented at the Third International Conference on Intelligent Systems for Molecular Biology which was held in the United Kingdom from July 16 to 19, 1995. In this paper, one objective is to identify properties of DNA sequences that determine their function, by computer-aided statistical analysis and to accurately predict its function, given a new sequence. A related problem is to predict protein structure and function from the sequence

SEQ: a nucleotide sequence analysis and recombination system

SEQ is an interactive, self-documenting computer program that contains procedures for the analysis of nucleotide sequences and the manipulation of such sequences to allow the simulation and prediction of the results of recombinant DNA experiments

Using Stochastic Roadmap Simulation to predict experimental quantities in protein folding kinetics: Folding rates and phi-values

10.1089/cmb.2007.R004Journal of Computational Biology145578-593JCOB