3 research outputs found
Definition of the Gene Content of the Human Genome: The Need for Deep Experimental Verification
Based on the analysis of the drafts of the human genome sequence, it is being speculated
that our species may possess an unexpectedly low number of genes. The quality of the
drafts, the impossibility of accurate gene prediction and the lack of sufficient transcript
sequence data, however, render such speculations very premature. The complexity of
human gene structure requires additional and extensive experimental verification of
transcripts that may result in major revisions of these early estimates of the number
of human genes