Pan arctic terrestrial snowmelt trends (1979–2008) from spaceborne passive microwave data and correlation with the Arctic Oscillation

We report pan-arctic terrestrial snowmelt trends for the period 1979 – 2008 derived from spaceborne microwave brightness temperature (Tb) and study the correlation between these trends and the Arctic Oscillation (AO). Melting is detected using a spatially and temporally dynamic algorithm using the difference between daytime and nighttime Tb values (Diurnal Amplitude Variations, DAV). Results indicate statistically significant negative trends for melt onset and end dates as well as for the length of the melt season. On the average, over the past 30 years melt has been starting (finishing) ∼0.5 days/year (∼1 days/year) earlier and the length of the melting season is shortening by ∼0.6 days/year. Results indicate that the AO index variability can explain up to 50% of the melt onset variability over Eurasia and only 10% of that over North America, consistent with spatial patterns of surface temperature changes related to the AO

Attribution of divergent northern vegetation growth responses to lengthening non-frozen seasons using satellite optical-NIR and microwave remote sensing

The non-frozen (NF) season duration strongly influences the northern carbon cycle where frozen (FR) temperatures are a major constraint to biological processes. The landscape freeze-thaw (FT) signal from satellite microwave remote sensing provides a surrogate measure of FR temperature constraints to ecosystem productivity, trace gas exchange, and surface water mobility. We analysed a new global satellite data record of daily landscape FT dynamics derived from temporal classification of overlapping SMMR and SSM/I 37 GHz frequency brightness temperatures (Tb). The FT record was used to quantify regional patterns, annual variability, and trends in the NF season over northern (≥45°N) vegetated land areas. The ecological significance of these changes was evaluated against satellite normalized difference vegetation index (NDVI) anomalies, estimated moisture and temperature constraints to productivity determined from meteorological reanalysis, and atmospheric CO2 records. The FT record shows a lengthening (2.4 days decade-1; p < 0.005) mean annual NF season trend (1979-2010) for the high northern latitudes that is 26% larger than the Northern Hemisphere trend. The NDVI summer growth response to these changes is spatially complex and coincides with local dominance of cold temperature or moisture constraints to productivity. Longer NF seasons are predominantly enhancing productivity in cold temperature-constrained areas, whereas these effects are reduced or reversed in more moisture-constrained areas. Longer NF seasons also increase the atmospheric CO2 seasonal amplitude by enhancing both regional carbon uptake and emissions. We find that cold temperature constraints to northern growing seasons are relaxing, whereas potential benefits for productivity and carbon sink activity are becoming more dependent on the terrestrial water balance and supply of plant-available moisture needed to meet additional water use demands under a warming climate. © 2014 Taylor & Francis

The dynamic and thermodynamic structure of the monsoon over southern India: new observations from the INCOMPASS IOP

Some of the highest summer monsoon rainfall in South Asia falls on the windward slopes of the Western Ghats mountains on India’s west coast and offshore over the eastern Arabian Sea. Understanding of the processes determining the spatial distribution and temporal variability of this region remains incomplete. In this paper, new Interaction of Convective Organization and Monsoon Precipitation, Atmosphere, Surface and Sea (INCOMPASS) aircraft and ground-based measurements of the summer monsoon over the Western Ghats and upstream of them are presented and placed within the context of remote sensing observations and reanalysis. The transition from widespread rainfall over the eastern Arabian Sea to rainfall over the Western Ghats is documented in high spatial and temporal resolution. Heavy rainfall offshore during the campaign was associated primarily with mid-tropospheric humidity, secondarily with sea surface temperature, and only weakly with orographic blocking. A mid-tropospheric dry intrusion suppressed deep convection offshore in the latter half of the campaign, allowing the build-up of low-level humidity in the onshore flow and enhancing rainfall over the mountains. Rainfall on the lee side of the Western Ghats occurred during the latter half of the campaign in association with enhanced mesoscale easterly upslope flow. Diurnal cycles in rainfall offshore (maximum in the morning) and on the mountains (maximum in the afternoon) were observed. Considerable zonal and temporal variability was seen in the offshore boundary layer, suggesting the presence of convective downdrafts and cold pools. Persistent drying of the subcloud mixed layer several hundred kilometres off the coast was observed, suggesting strong mixing between the boundary layer and the free troposphere. These observations provide quantitative targets to test models and suggest hypotheses on the physical mechanisms determining the distribution and variability in rainfall in the Western Ghats region

TRStalker: an efficient heuristic for finding fuzzy tandem repeats

Motivation: Genomes in higher eukaryotic organisms contain a substantial amount of repeated sequences. Tandem Repeats (TRs) constitute a large class of repetitive sequences that are originated via phenomena such as replication slippage and are characterized by close spatial contiguity. They play an important role in several molecular regulatory mechanisms, and also in several diseases (e.g. in the group of trinucleotide repeat disorders). While for TRs with a low or medium level of divergence the current methods are rather effective, the problem of detecting TRs with higher divergence (fuzzy TRs) is still open. The detection of fuzzy TRs is propaedeutic to enriching our view of their role in regulatory mechanisms and diseases. Fuzzy TRs are also important as tools to shed light on the evolutionary history of the genome, where higher divergence correlates with more remote duplication events

Evolution of Plant-Made Pharmaceuticals

The science and policy of pharmaceuticals produced and/or delivered by plants has evolved over the past twenty-one years from a backyard remedy to regulated, purified products. After seemingly frozen at Phase I human clinical trials with six orally delivered plant-made vaccines not progressing past this stage over seven years, plant-made pharmaceuticals have made a breakthrough with several purified plant-based products advancing to Phase II trials and beyond. Though fraught with the usual difficulties of pharmaceutical development, pharmaceuticals made by plants have achieved pertinent milestones albeit slowly compared to other pharmaceutical production systems and are now at the cusp of reaching the consumer. Though the current economic climate begs for cautious investment as opposed to trail blazing, it is perhaps a good time to look to the future of plant-made pharmaceutical technology to assist in planning for future developments in order not to slow this technology’s momentum. To encourage continued progress, we highlight the advances made so far by this technology, particularly the change in paradigms, comparing developmental timelines, and summarizing the current status and future possibilities of plant-made pharmaceuticals

Hierarchical structure of cascade of primary and secondary periodicities in Fourier power spectrum of alphoid higher order repeats

<p>Abstract</p> <p>Background</p> <p>Identification of approximate tandem repeats is an important task of broad significance and still remains a challenging problem of computational genomics. Often there is no single best approach to periodicity detection and a combination of different methods may improve the prediction accuracy. Discrete Fourier transform (DFT) has been extensively used to study primary periodicities in DNA sequences. Here we investigate the application of DFT method to identify and study alphoid higher order repeats.</p> <p>Results</p> <p>We used method based on DFT with mapping of symbolic into numerical sequence to identify and study alphoid higher order repeats (HOR). For HORs the power spectrum shows equidistant frequency pattern, with characteristic two-level hierarchical organization as signature of HOR. Our case study was the 16 mer HOR tandem in AC017075.8 from human chromosome 7. Very long array of equidistant peaks at multiple frequencies (more than a thousand higher harmonics) is based on fundamental frequency of 16 mer HOR. Pronounced subset of equidistant peaks is based on multiples of the fundamental HOR frequency (multiplication factor <it>n </it>for <it>n</it>mer) and higher harmonics. In general, <it>n</it>mer HOR-pattern contains equidistant secondary periodicity peaks, having a pronounced subset of equidistant primary periodicity peaks. This hierarchical pattern as signature for HOR detection is robust with respect to monomer insertions and deletions, random sequence insertions etc. For a monomeric alphoid sequence only primary periodicity peaks are present. The 1/<it>f</it>^{<it>β </it>}– noise and periodicity three pattern are missing from power spectra in alphoid regions, in accordance with expectations.</p> <p>Conclusion</p> <p>DFT provides a robust detection method for higher order periodicity. Easily recognizable HOR power spectrum is characterized by hierarchical two-level equidistant pattern: higher harmonics of the fundamental HOR-frequency (secondary periodicity) and a subset of pronounced peaks corresponding to constituent monomers (primary periodicity). The number of lower frequency peaks (secondary periodicity) below the frequency of the first primary periodicity peak reveals the size of <it>n</it>mer HOR, i.e., the number <it>n </it>of monomers contained in consensus HOR.</p

Numerical analysis of thermal loaded effect on displacement and stress conditions of concrete aprons

Artykuł przedstawia analizę betonowych płyt nawierzchniowych poddanych obciążeniom termicznym. Zasadniczą część artykułu podzielono na trzy rozdziały. W pierwszym rozdziale analizą objęto pojedynczą nieważką płytę betonową obciążoną termicznie, dla której pominięto wpływ jej ciężaru własnego oraz wpływ oddziaływania podłoża. W drugim rozdziale zaprezentowano możliwości wykorzystania analiz numerycznych w doborze podstawowych parametrów płyt oraz podłoża. Rozważano wpływ zamiany wymiarów płyty w planie oraz grubości i sztywności podłoża na stan przemieszczeń i naprężeń. Dodatkowo w trzecim rozdziale przeprowadzono analizę z wykorzystaniem superpozycji obciążeń wywołanych naciskami kół samolotu oraz termicznych. Wyniki tych analiz przedstawiono w postaci rozkładów warstwicowych oraz w postaci graficznych zestawień porównawczych. Artykuł zakończono podsumowaniem.The article presents an analysis of concrete aprons subjected to therminal load. Main part of the article is divided into three chapters. First chapter includes the analysis of a single weightless concrete apron, subjected to thermal load, where deadweight and base interaction effect is omitted. Second chapter presents the possibilities of the use of numerical analysis for selecting basic parameters of apron and base. Influence of apron dimensions and thickness, base rigidity and displacement and stress conditions were considered. Third chapter includes the analysis, using superposition method for loads caused by thrust of aircraft wheels and thermal loads. Results of the analysis are presented in form of a contour plan and graphical comparison. Article is concluded with a summary