Clinical features and the factors associated with poor outcome of measles patients at Queen Elizabeth Central Hospital

In the twelve month period from March 1992 to February 1993. 266 consecutive children with measles were admitted to the children's unit at Queen Elizabeth Central Hospital (QECH). Blantyre. During the 12 month period the overall mortality was 10.9%; mortality was highest (22.5%) in children 12-23 months age. One-third of the children admitted were under 9 months of age. not eligible for measles vaccination. Pneumonia complicated illness of 30% of cases and was the greatest clinical predictor of mortality. Among infants under 9 months of age, who were receiving inappropriate food supplementation before 4 months of age the risk of death was 6.4 times the risk of death in children who were not receiving food supplementation. Other aspects of measles epidemiology are discussed

Depression in Zimbabwe: a community approach to prevention and treatment

A position paper on primary health care for the management of mental health in Zimbabwe.This paper reports on a process whereby research findings, generated by a collaborative project between primary health care workers and a University team, were utilized by a community to formulate local plans for the prevention and management of depression. Action-oriented research, with a high level of community participation, follows on directly from the Declaration of Alma-Ata1 and has been called Health Systems Research (HSR). The principle of HSR is that it should be useful and have a direct focus on solving practical and relevant problems.2 Priorities should be generated by health workers and by the community rather than purely by academics and as much as possible of the research should be carried out by those already working at ground level. Results should lead to implementable recommendations and the research is not complete until those recommendations are underway

The significance of 'the visit' in an English category-B prison: Views from prisoners, prisoners' families and prison staff

A number of claims have been made regarding the importance of prisoners staying in touch with their family through prison visits, firstly from a humanitarian perspective of enabling family members to see each other, but also regarding the impact of maintaining family ties for successful rehabilitation, reintegration into society and reduced re-offending. This growing evidence base has resulted in increased support by the Prison Service for encouraging the family unit to remain intact during a prisoner’s incarceration. Despite its importance however, there has been a distinct lack of research examining the dynamics of families visiting relatives in prison. This paper explores perceptions of the same event – the visit – from the families’, prisoners’ and prison staffs' viewpoints in a category-B local prison in England. Qualitative data was collected with 30 prisoners’ families, 16 prisoners and 14 prison staff, as part of a broader evaluation of the visitors’ centre. The findings suggest that the three parties frame their perspective of visiting very differently. Prisoners’ families often see visits as an emotional minefield fraught with practical difficulties. Prisoners can view the visit as the highlight of their time in prison and often have many complaints about how visits are handled. Finally, prison staff see visits as potential security breaches and a major organisational operation. The paper addresses the current gap in our understanding of the prison visit and has implications for the Prison Service and wider social policy

Maize terpene synthase 1 impacts insect behavior via the production of monoterpene volatiles \u3ci\u3eβ\u3c/i\u3e-myrcene and linalool

Plant-derived volatiles are important mediators of plant-insect interactions as they can provide cues for host location and quality, or act as direct or indirect defense molecules. The volatiles produced by Zea mays (maize) include a range of terpenes, likely produced by several of the terpene synthases (TPS) present in maize. Determining the roles of specific terpene volatiles and individual TPSs in maize-insect interactions is challenging due to the promiscuous nature of TPSs in vitro and their potential for functional redundancy. In this study, we used metabolite GWAS of a sweetcorn diversity panel infested with Spodoptera frugiperda (fall armyworm) to identify genetic correlations between TPSs and individual volatiles. This analysis revealed a correlation between maize terpene synthase 1 (ZmTPS1) and emission of the monoterpene volatiles linalool and β-myrcene. Electroantennogram assays showed gravid S. frugiperda could detect both linalool and β-myrcene. Quantification of headspace volatiles in a maize tps1 loss-of-function mutant confirmed that ZmTPS1 is an important contributor to linalool and β-myrcene emission in maize. Furthermore, pairwise choice assays between tps1 mutant and wildtype plants showed that ZmTPS1, and by extension its volatile products, aid host location in the chewing insect S. frugiperda, yet repel the sap-sucking pest, Rhopalosiphum maidis (corn leaf aphid). On the other hand, ZmTPS1 had no impact on indirect defense via the recruitment of the parasitoid Cotesia marginiventris. ZmTPS1 is therefore an important mediator of the interactions between maize and its insect pests

The micropolitics of quality

This paper discusses how the audit culture has impacted on UK academics in terms of professional identities, priorities and social relations. Micropolitics, performativity, psychic economy and the changing political economy of higher education are some of the theoretical tools used to offer some explanatory power for the range of engagements with quality assurance. Questions are raised about the polysemic discourse of quality and how it has been subjected to multiple interpretations. For example, there are those members of the academy who see it as a major form of modernisation and student empowerment, while others see it as a form of symbolic violence. Specific attention is paid to peer review, impact studies, gendered power relations, productivity measures and whether quality intersects with equality in the academy. The paper concludes with calls to consider what the gestalt is of higher education

Growth of Inflaton Perturbations and the Post-Inflation Era in Supersymmetric Hybrid Inflation Models

It has been shown that hybrid inflation may end with the formation of non-topological solitons of inflaton field. As a first step towards a fully realistic picture of the post-inflation era and reheating in supersymmetric hybrid inflation models, we study the classical scalar field equations of a supersymmetric hybrid inflation model using a semi-analytical ansatz for the spatial dependence of the fields. Using the minimal D-term inflation model as an example, the inflaton field is evolved using the full 1-loop effective potential from the slow-rolling era to the U(1)_{FI} symmetry-breaking phase transition. Spatial perturbations of the inflaton corresponding to quantum fluctuations are introduced for the case where there is spatially coherent U(1)_{FI} symmetry breaking. The maximal growth of the dominant perturbation is found to depend only on the ratio of superpotential coupling \lambda to the gauge coupling g. The inflaton condensate fragments to non-topological solitons for \lambda/g > 0.09. Possible consequences of non-topological soliton formation in fully realistic SUSY hybrid inflation models are discussed.Comment: 27 pages LaTeX, 8 figures. Additional references and discussio

A funds of knowledge approach to examining play interests: listening to children’s and parents’ perspectives.

Children’s interests are widely recognised as pivotal to meaningful learning and play in the early years. However, less is known about how children’s diverse interests may contribute to relationships within peer cultures. This article builds upon previous studies to argue that participation in sociocultural activity generates interests informed by funds of knowledge that children reconstruct in their play. It reports findings from an interpretive study that used filmed footage of children’s play as a provocation to explore the perspectives of children, parents and teachers. The article presents original insights regarding some ways in which mutually constituted funds of knowledge afford opportunities for children to co-construct meaning within peer cultures. The findings also indicate that interests arising from diverse funds of knowledge may contribute to the interplay of power, agency and status during play. This raises some issues regarding how matters of inclusion and exclusion are understood and responded to within early years settings. The article recommends that teachers and researchers engage critically with children’s individual and collective funds of knowledge in order to better understand the complexities of play cultures