1,042 research outputs found

    Full-scale aircraft cabin flammability tests of improved fire-resistant materials, test series 2

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    Full-scale aircraft flammability tests in which the effectiveness of new fire-resistant materials was evaluated by comparing their burning characteristics with those of other fire-resistant aircraft materials were described. New-fire-resistant materials that are more economical and better suited for aircraft use than the previously tested fire-resistant materials were tested. The fuel ignition source for one test was JP-4; a smokeless fuel was used for the other test. Test objectives, methods, materials, and results are presented and discussed. The results indicate that, similar to the fire-resistant materials tested previously, the new materials decompose rather than ignite and do not support fire propagation. Furthermore, the new materials did not produce a flash fire

    National underground assets and subsurface data : review of use case applications. Iceberg Industry Group workshop

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    The Iceberg Industry Group represents over 130 organisations who are committed to the improvement of the capture and sharing of information that relates to the subsurface. The open community was formed following the publication of research (Project Iceberg, 2018) into a framework to address shortfalls in subsurface data. The research also informed subsequent programmes, most notably the National Underground Asset Register (NUAR) pilot projects delivered by the Greater London Authority and the Ordnance Survey, funded by the Geospatial Commission (2019). NUAR currently focuses on the development of an underground utility asset register for strike avoidance, with the benefits aligned to Health and Safety related outcomes and planning efficiencies. Working in partnership with the Geospatial Commission (GC), the Iceberg Industry Group delivered a workshop (Nov 2019) looking at additional applications and benefits, (over-and-above strike avoidance), that may be realised by the creation of an underground asset register and better subsurface data use. The workshop was facilitated by British Geological Survey and Ordnance Survey. This report presents a summary of the workshop and its findings

    One-step isolation and biochemical characterization of a highlyactive plant PSII monomeric core

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    We describe a one-step detergent solubilization protocol for isolating a highly active form of Photosystem II (PSII) from Pisum sativum L. Detailed characterization of the preparation showed that the complex was a monomer having no light harvesting proteins attached. This core reaction centre complex had, however, a range of low molecular mass intrinsic proteins as well as the chlorophyll binding proteins CP43 and CP47 and the reaction centre proteins D1 and D2. Of particular note was the presence of a stoichiometric level of PsbW, a low molecular weight protein not present in PSII of cyanobacteria. Despite the high oxygen evolution rate, the core complex did not retain the PsbQ extrinsic protein although there was close to a full complement of PsbO and PsbR and partial level of PsbP. However, reconstitution of PsbP and PsbPQ was possible. The presence of PsbP in absence of LHCII and other chlorophyll a/b binding proteins confirms that LHCII proteins are not a strict requirement for the assembly of this extrinsic polypeptide to the PSII core in contrast with the conclusion of Caffarri et al. (2009)

    Factors That Impact the Success of Interorganizational Health Promotion Collaborations: A Scoping Review

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    © 2017, © The Author(s) 2017. Objective: To explore published empirical literature in order to identify factors that facilitate or inhibit collaborative approaches for health promotion using a scoping review methodology. Data Source: A comprehensive search of MEDLINE, CINAHL, ScienceDirect, PsycINFO, and Academic Search Complete for articles published between January 2001 and October 2015 was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Study Inclusion and Exclusion Criteria: To be included studies had to: be an original research article, published in English, involve at least 2 organizations in a health promotion partnership, and identify factors contributing to or constraining the success of an established (or prior) partnership. Studies were excluded if they focused on primary care collaboration or organizations jointly lobbying for a cause. Data Extraction: Data extraction was completed by 2 members of the author team using a summary chart to extract information relevant to the factors that facilitated or constrained collaboration success. Data Synthesis: NVivo 10 was used to code article content into the thematic categories identified in the data extraction. Results: Twenty-five studies across 8 countries were identified. Several key factors contributed to collaborative effectiveness, including a shared vision, leadership, member characteristics, organizational commitment, available resources, clear roles/responsibilities, trust/clear communication, and engagement of the target population. Conclusion: In general, the findings were consistent with previous reviews; however, additional novel themes did emerge

    Theoretical studies of the historical development of the accounting discipline: a review and evidence

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    Many existing studies of the development of accounting thought have either been atheoretical or have adopted Kuhn's model of scientific growth. The limitations of this 35-year-old model are discussed. Four different general neo-Kuhnian models of scholarly knowledge development are reviewed and compared with reference to an analytical matrix. The models are found to be mutually consistent, with each focusing on a different aspect of development. A composite model is proposed. Based on a hand-crafted database, author co-citation analysis is used to map empirically the entire literature structure of the accounting discipline during two consecutive time periods, 1972–81 and 1982–90. The changing structure of the accounting literature is interpreted using the proposed composite model of scholarly knowledge development

    Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism.

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    Most differentiated cells convert glucose to pyruvate in the cytosol through glycolysis, followed by pyruvate oxidation in the mitochondria. These processes are linked by the mitochondrial pyruvate carrier (MPC), which is required for efficient mitochondrial pyruvate uptake. In contrast, proliferative cells, including many cancer and stem cells, perform glycolysis robustly but limit fractional mitochondrial pyruvate oxidation. We sought to understand the role this transition from glycolysis to pyruvate oxidation plays in stem cell maintenance and differentiation. Loss of the MPC in Lgr5-EGFP-positive stem cells, or treatment of intestinal organoids with an MPC inhibitor, increases proliferation and expands the stem cell compartment. Similarly, genetic deletion of the MPC in Drosophila intestinal stem cells also increases proliferation, whereas MPC overexpression suppresses stem cell proliferation. These data demonstrate that limiting mitochondrial pyruvate metabolism is necessary and sufficient to maintain the proliferation of intestinal stem cells

    Search for Light Gluinos via the Spontaneous Appearance of pi+pi- Pairs with an 800 GeV/c Proton Beam at Fermilab

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    We searched for the appearance of pi+pi- pairs with invariant mass greater than 648 MeV in a neutral beam. Such an observation could signify the decay of a long-lived light neutral particle. We find no evidence for this decay. Our null result severely constrains the existence of an R0 hadron, which is the lightest bound state of a gluon and a light gluino, and thereby also the possibility of a light gluino. Depending on the photino mass, we exclude the R0 in the mass and lifetime ranges of 1.2 -- 4.6 GeV and 2E-10 -- 7E-4 seconds, respectively. (To Appear in Phys. Rev. Lett.)Comment: Documentstyle aps,epsfig,prl (revtex), 6 pages, 7 figure
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