Neuromas of the Trochlear Nerve

Fourth nerve palsies that are atypical in presentation and do not resolve spontaneously may be due to a neuroma

Neatly Coiffed Lad with Progressive Seizures

Loss of vision OU; Cognitive deficits; Dysarthria; Gait disturbances; SeizuresA 23-year-old male with a progressive neurodegenerative disorder and blindness.VA: LPO OUMRILysosomal inclusions; Cytoplasmic curvilinear and fingerprint bodiesN/A1. Beck RW. Chapter 14: Abnormalities of the optic nerve and retina. Boston: Butterworth-Heinemann, 1991. 2. Janeway R, Ravens JR, Pearce LA, Odor DL, Suzuki K. Progressive myclonus epilepsy with Lafora inclusion bodies. 1. Clinical, genetic, histopathologic and biochemical aspects. Archives Neurology 1967;16:565-582. 3. van Dijk JG, vander Velde EA, Roos RAC, Bruyn GW. Juvenile Huntington disease. Human Genetics 1986;73:235-239. 4. Halliday W. The nosology of Hallervorden-Spatz disease. J Neurol Sci 1995;134:84-91. 5. Leonard JV, Schapira AH. Mitochondrial respiratory chain disorders II: neurodegenerative disorders and nuclear gene defects. Lancet 2000;355:389-94. 6 Bennett MJ, Hofmann SL. The neuronal ceroid-lipofuscinoses (Batten disease): a new class of lysosomal storage diseases. Journal of Inherited Metabolic Disease 1999;22:535-44. 7. Goebel HH, Sharp JD. The neuronal ceroid-lipofuscinoses. Recent advances. Brain Pathology 1998;8:151-62. 8. Hofmann SL, Das AK, Yi W, Lu JY, Wisniewski KE. Genotype-phenotype correlations in neuronal ceroid lipofuscinosis due to palmityol-protein thioesterase deficiency. Molecular Genetics & Metabolism 1999;66:234-9. 9. Mole S, Gardiner M. Molecular genetics of the neuronal ceroid lipofuscinoses. Epilepsia 1999;40:29-32. 10. Goebel HH, Schochet SS, Jaynes M, Bruck W, Kohlschutter A, Hentati F. Progress in neuropathology of the neuronal ceroid lipofuscinoses. Molecular Genetics & Metabolism 1999;66:367-72.VBmetabolicstoragedisorder

Ischemic Optic Neuropathy During Amiodarone Therapy

Ischemic optic neuropathy has been found in a number of Amiodarone treated patients. The clinical apppearance and severity of the neuropathy is milder than that classically described. The incidence of occurence has been shown to be significantly higher than that expected in the general population. Whether this is due solely to Amiodarone therapy, to the underlying poor health of these patients, or to a combination of the two is uncertain

A New Pupillography Machine

Mayo Clinic Engineers and the Department of Ophthalmology have combined efforts In the production of a new prototype double channel pupillography machine that consists of two small TV cameras sensitive to the Infra-red spectrum, a movable arm, laser fiXation point, and an IBM computer system for analysis and display of the data. A printout of the pupil sizes, time constants and other data Is done with a color graphics printer

Aerospace Disorientation & the Vomit Comet

Vision is by far the most important of the senses in aerospace travel. Because of the adaptability of the human mind to changing situations, it is unlikely that unmanned fighter interceptors, airliners and space ships destined for complex missions will supersede the human interface within the cockpit

Dynamic Spatial Reconstruction

The dynamic spatial reconstructor (DSR) is a three dimensional imaging device that uses the principles of standard computerized scanners with several advantages

Oscillopsia and Rotary Nystagmus, Synchronous with Heartbeat: A Treatable Form of Nystagmus

Two patients with oscillopsia and a rotary nystagmus synchronous with heartbeat were found in addition to have Valsalva-induced nystagmus

Practical Demonstration of the Lancaster red-Green Test in Myasthenia Gravis

In a multi-trauma victim if the surgeon even thinks about doing a tracheostomy, he should probably have already done it

Iatrogenic Functional Visual Loss

With an increasingly complex armamentarium of sophisticated diagnostic studies used to ply our patients, there is a tendency to forget to be a clinician, and make the diagnosis on the basis of common sense and the material at hand. There is emerging from the morass of high-tech neuro-ophthalmic massage parlors a whole cadre of patients whose problems may have started out relatively simple, albeit unexplained, who having suffered not only from their original symptoms, then assume a largely functional component to their visual loss that is aided and abetted by the continued tests without answers, and the insecurity of perplexed and puzzled clinicians

If You Were the Doctor?

A 62 year old physician presented with slight proptosis and an inferiorly displaced left eye. Vision was minimally impaired, 20/30 on the left, and a subtle left afferent pupillary defect was noted. Periocular discomfort, visual loss and proptosis were slowly progressive