Tissue-specific gene expression of <i>RBFOX1</i> from GTEx database (http://www.gtexportal.org/home/gene/RBFOX1).

<p>Tissue-specific gene expression of <i>RBFOX1</i> from GTEx database (<a href="http://www.gtexportal.org/home/gene/RBFOX1" target="_blank">http://www.gtexportal.org/home/gene/RBFOX1</a>).</p

Linkage region on chromosome 16 of white participants in CFS.

<p>Linkage peak on chromosome 16 for SBP. The linkage curves are plotted with (red curve) and without (blue curve) adjusting for the risk score defined by the 13 coding variants as a covariate. The positions of the 13 coding variants are listed under the linkage peak and above the genes.</p

Results of gene-based analysis in discovery data and replication cohorts.

<p>Results of gene-based analysis in discovery data and replication cohorts.</p

The CFS family carrying the protective rare variant rs149974858.

<p>A) The variant rs149974858 segregates with BP in a 17-member CFS family. Squares represent males and circles represent females. Half-filled subjects represent the carriers of the rare variant rs149974858. Grey subjects represent no information. Age of each subject is presented in parenthesis. B) The distribution of corresponding residuals of SBP, DBP, PP and BMI are presented.</p

Characteristics of white participants in the Cleveland Family Study.

<p>Characteristics of white participants in the Cleveland Family Study.</p

Novel and previously identified BMI and WHR_adjBMI loci at <i>P</i> < 5×10⁻⁸ in African ancestry discovery and replication samples, and European ancestry replication samples.

<p>Novel and previously identified BMI and WHR_adjBMI loci at <i>P</i> < 5×10⁻⁸ in African ancestry discovery and replication samples, and European ancestry replication samples.</p

Additional novel BMI and WHR_adjBMI loci at <i>P</i> < 5×10⁻⁸ in sex-stratified analyses of African ancestry discovery and replication samples.

<p>Additional novel BMI and WHR_adjBMI loci at <i>P</i> < 5×10⁻⁸ in sex-stratified analyses of African ancestry discovery and replication samples.</p