Poverty and inequality in the UK: 2007

This Briefing Note provides an update on trends in living standards, income inequality and poverty. It uses the same approach to measuring income and poverty as the government employs in its Households Below Average Income (HBAI) publication. The analysis is based on the latest HBAI figures (published on 27 March 2007), providing information about incomes up to the year 2005-06. The measure of income used is net household weekly income, which has been adjusted to take account of family size ('equivalised'). The income amounts provided below are expressed as the equivalent for a couple with no children, and all changes given are in real terms (i.e. after adjusting for inflation). For the first time in recent years, data are available for the whole of the United Kingdom, not just Great Britain, but data for Northern Ireland are only available from 2002-03. Some comparisons over time are provided for Great Britain only, but others will compare statistics for GB before 2002-03 with those for the UK afterwards. PLEASE NOTE: On 23 April 2007, the Department for Work and Pensions announced that an error had occurred when producing the latest Households Below Average Income publication. This Briefing Note was based on the same dataset and therefore suffers from similar errors. In response to revisions announced by the DWP in May 2007, we have now updated our findings in a revised press release and have produced a revised summary

Poverty and inequality in Britain: 2006

This Commentary provides an update on trends in poverty and inequality in Great Britain, based on the latest official government statistics. It uses the same approach to measuring incomes and poverty in Great Britain as the government employs in its Households Below Average Income (HBAI) publication

Poverty and Inequality in the UK: 2008

In this Commentary, we assess the changes to average incomes, inequality and poverty that have occurred under the first 10 years of the Labour government, with a particular focus on the changes that have occurred in the latest year of data. This analysis is based upon the latest figures from the DWP's Households Below Average Income (HBAI) series, published on 10 June 2008 (Department for Work and Pensions, 2008c). The HBAI series takes household income as its measure of living standards and is derived from the Family Resources Survey, a survey of around 28,000 households in the United Kingdom that asks detailed questions about income from a range of sources

Poverty and inequality in the UK: 2009

In this Commentary, we assess the changes to average incomes, inequality and poverty that have occurred since Labour came to power in 1997, with a particular focus on the changes that have occurred in the latest year of data. This analysis is based upon the latest figures from the DWP's Households Below Average Income (HBAI) series, published on 7 May 2009 (Department for Work and Pensions, 2009). The HBAI series takes household income as its measure of living standards, and is derived from the Family Resources Survey, a survey of around 25,000 households in the United Kingdom that asks detailed questions about income from a range of sources

Comparison of Porcelain Surface and Flexural Strength Obtained by Microwave and Conventional Oven Glazing

Statement of problem. Although the superior qualities of microwave technology are common knowledge in the industry, effects of microwave glazing of dental ceramics have not been investigated. Purpose. The purpose of this study was to investigate the surface roughness and flexural strength achieved by glazing porcelain specimens in a conventional and microwave oven. Material and methods. Thirty specimens of each type of porcelain (Omega 900 and IPS d.Sign) were fabricated and sintered in a conventional oven. The specimens were further divided into 3 groups (n=10): hand polished (using diamond rotary ceramic polishers), microwave glazed, and conventional oven glazed. Each specimen was evaluated for surface roughness using a profilometer. The flexural strength of each specimen was measured using a universal testing machine. A 2-way ANOVA and Tukey HSD post hoc analysis were used to determine significant intergroup differences in surface roughness (α=.05). Flexural strength results were also analyzed using 2-way ANOVA, and the Weibull modulus was determined for each of the 6 groups. The surfaces of the specimens were subjectively evaluated for cracks and porosities using a scanning electron microscope (SEM). Results. A significant difference in surface roughness was found among the surface treatments (P=.02). Follow-up tests showed a significant difference in surface roughness between oven-glazed and microwave-glazed treatments (P=.02). There was a significant difference in flexural strength between the 2 porcelains (P Conclusions. The surface character of microwave-glazed porcelain was superior to oven-glazed porcelain. Omega 900 had an overall higher flexural strength than IPS d.Sign. Weibull distributions of flexural strengths for Omega 900 ovenglazed and microwave-glazed specimens were similar. SEM analysis demonstrated a greater number of surface voids and imperfections in IPS d.Sign as compared to Omega 900

Optimizing real time fMRI neurofeedback for therapeutic discovery and development

While reducing the burden of brain disorders remains a top priority of organizations like the World Health Organization and National Institutes of Health, the development of novel, safe and effective treatments for brain disorders has been slow. In this paper, we describe the state of the science for an emerging technology, real time functional magnetic resonance imaging (rtfMRI) neurofeedback, in clinical neurotherapeutics. We review the scientific potential of rtfMRI and outline research strategies to optimize the development and application of rtfMRI neurofeedback as a next generation therapeutic tool. We propose that rtfMRI can be used to address a broad range of clinical problems by improving our understanding of brain-behavior relationships in order to develop more specific and effective interventions for individuals with brain disorders. We focus on the use of rtfMRI neurofeedback as a clinical neurotherapeutic tool to drive plasticity in brain function, cognition, and behavior. Our overall goal is for rtfMRI to advance personalized assessment and intervention approaches to enhance resilience and reduce morbidity by correcting maladaptive patterns of brain function in those with brain disorders

Antigen depot is not required for alum adjuvanticity

Alum adjuvants have been in continuous clinical use for more than 80 yr. While the prevailing theory has been that depot formation and the associated slow release of antigen and/or inflammation are responsible for alum enhancement of antigen presentation and subsequent T- and B-cell responses, this has never been formally proven. To examine antigen persistence, we used the chimeric fluorescent protein EαGFP, which allows assessment of antigen presentation in situ, using the Y-Ae antibody. We demonstrate that alum and/or CpG adjuvants induced similar uptake of antigen, and in all cases, GFP signal did not persist beyond 24 h in draining lymph node antigen-presenting cells. Antigen presentation was first detectable on B cells within 6–12 h of antigen administration, followed by conventional dendritic cells (DCs) at 12–24 h, then finally plasmacytoid DCs at 48 h or later. Again, alum and/or CpG adjuvants did not have an effect on the magnitude or sequence of this response; furthermore, they induced similar antigen-specific T-cell activation in vivo. Notably, removal of the injection site and associated alum depot, as early as 2 h after administration, had no appreciable effect on antigen-specific T- and B-cell responses. This study clearly rules out a role for depot formation in alum adjuvant activity

A Molecular Einstein Ring at z=4.12: Imaging the Dynamics of a Quasar Host Galaxy Through a Cosmic Lens

We present high-resolution (0.3") Very Large Array (VLA) imaging of the molecular gas in the host galaxy of the high redshift quasar PSS J2322+1944 (z=4.12). These observations confirm that the molecular gas (CO) in the host galaxy of this quasar is lensed into a full Einstein ring, and reveal the internal dynamics of the molecular gas in this system. The ring has a diameter of ~1.5", and thus is sampled over ~20 resolution elements by our observations. Through a model-based lens inversion, we recover the velocity gradient of the molecular reservoir in the quasar host galaxy of PSS J2322+1944. The Einstein ring lens configuration enables us to zoom in on the emission and to resolve scales down to ~1 kpc. From the model-reconstructed source, we find that the molecular gas is distributed on a scale of 5 kpc, and has a total mass of M(H2)=1.7 x 10^10 M_sun. A basic estimate of the dynamical mass gives M_dyn = 4.4 x 10^10 (sin i)^-2 M_sun, that is, only ~2.5 times the molecular gas mass, and ~30 times the black hole mass (assuming that the dynamical structure is highly inclined). The lens configuration also allows us to tie the optical emission to the molecular gas emission, which suggests that the active galactic nucleus (AGN) does reside within, but not close to the center of the molecular reservoir. Together with the (at least partially) disturbed structure of the CO, this suggests that the system is interacting. Such an interaction, possibly caused by a major `wet' merger, may be responsible for both feeding the quasar and fueling the massive starburst of 680 M_sun/yr in this system, in agreement with recently suggested scenarios of quasar activity and galaxy assembly in the early universe.Comment: 9 pages, 7 figures, to appear in ApJ (accepted June 27, 2008