2 research outputs found
Thyroid function within the normal range and risk of coronary heart disease an individual participant data analysis of 14 cohorts
IMPORTANCE Some experts suggest that serum thyrotropin levels in the upper part of the
current reference range should be considered abnormal, an approach that would reclassify
many individuals as having mild hypothyroidism. Health hazards associated with such
thyrotropin levels are poorly documented, but conflicting evidence suggests that thyrotropin
levels in the upper part of the reference range may be associated with an increased risk of
coronary heart disease (CHD).
OBJECTIVE To assess the association between differences in thyroid function within the
reference range and CHD risk.
DESIGN, SETTING, AND