519 research outputs found
A new method of quantization of classical solutions
Using stochastic quantization method we derive equations for correlators of
quantum fluctuations around the classical solution in the massless phi^4
theory. The obtained equations are then solved in the lowest orders of
perturbation theory, and the first correction to the free propagator of a
quantum fluctuation is calculated.Comment: 8 page
Distribution of major anions and trace elements in the unsaturated zone at Franklin Lake Playa, California, USA
The composition of surficial salts formed near dry and drying saline lakes are partly the product of processes active in the unsaturated zone between the ground surface and the water table. These processes were investigated by determining the abundance of water-extractable solutes in sediment from the ground surface to the water table (~2.8 m) beneath Franklin Lake playa, California. Accumulation of solutes in the sediment is attributed to evaporation of aqueous solutions transported upward from the water table through the capillary fringe to an evaporation font that is currently 20-30 cm below the ground surface. Salts in the sediment from 0 to 20 cm depth are depleted in chloride and enriched in carbonate relative to deeper samples. Chloride depletion is most likely a product of selective dissolution by vertical recharge. The entire unsaturated zone contains greater amounts of carbonate than expected for evaporation of ground water and is best explained by preferential dissolution of more soluble salts in recharging precipitation but may also reflect the assimilation of CO2 as carbonate minerals precipitate. Variations in the concentrations of arsenic, molybdenum, tungsten, and uranium in the water-soluble fraction of the sediment are complex and suggest unique geochemical controls on the abundance of each element. The distribution of these trace element abundances indicates the arsenic is the element most likely to accumulate in near-surface salts
On the evaluation of some three-body variational integrals
Stable recursive relations are presented for the numerical computation of the
integrals
(, and integer, , and real) when the
indices , or are negative. Useful formulas are given for particular
values of the parameters , and .Comment: 12 pages, 1 figure (PS) and 3 tables. Old figures 2 and 3 replaced by
Tables I and III. A further table added. Paper enlarged giving some tips on
the convergence of quadrature
Correlated many-body treatment of Breit interaction with application to cesium atomic properties and parity violation
Corrections from Breit interaction to basic properties of atomic 133Cs are
determined in the framework of third-order relativistic many-body perturbation
theory. The corrections to energies, hyperfine-structure constants,
off-diagonal hyperfine 6S-7S amplitude, and electric-dipole matrix elements are
tabulated. It is demonstrated that the Breit corrections to correlations are
comparable to the Breit corrections at the Dirac-Hartree-Fock level.
Modification of the parity-nonconserving (PNC) 6S-7S amplitude due to Breit
interaction is also evaluated; the resulting weak charge of Cs shows no
significant deviation from the prediction of the standard model of elementary
particles. The neutron skin correction to the PNC amplitude is also estimated
to be -0.2% with an error bound of 30% based on the analysis of recent
experiments with antiprotonic atoms. The present work supplements publication
[A. Derevianko, Phys. Rev. Lett. 85, 1618 (2000)] with a discussion of the
formalism and provides additional numerical results and updated discussion of
parity violation.Comment: 16 pages; 5 figs; submitted to Phys. Rev.
Role of Present and Future Atomic Parity Violation Experiments in Precision Electroweak Tests
Recent reanalyses of the atomic physics effects on the weak charge in cesium
have led to a value in much closer agreement with predictions of the Standard
Model. We review precision electroweak tests, their implications for upper
bounds on the mass of the Higgs boson, possible ways in which these bounds may
be circumvented, and the requirements placed upon accuracy of future atomic
parity violation experiments by these considerations.Comment: 10 pages, LaTeX, 1 figure, to be submitted to Physical Review D, new
data on neutrino deep inelastic scattering include
Combined STN/SNr-DBS for the treatment of refractory gait disturbances in Parkinson's disease: study protocol for a randomized controlled trial
<p>Abstract</p> <p>Background</p> <p>Severe gait disturbances in idiopathic Parkinson's disease (PD) are observed in up to 80% of all patients in advanced disease stages with important impact on quality of life. There is an unmet need for further symptomatic therapeutic strategies, particularly as gait disturbances generally respond unfavourably to dopaminergic medication and conventional deep brain stimulation of the subthalamic nucleus in advanced disease stages. Recent pathophysiological research pointed to nigro-pontine networks entrained to locomotor integration. Stimulation of the pedunculopontine nucleus is currently under investigation, however, hitherto remains controversial. The substantia nigra pars reticulata (SNr) - entrained into integrative locomotor networks - is pathologically overactive in PD. High-frequent stimulation of the substantia nigra pars reticulata preferentially modulated axial symptoms and therefore is suggested as a novel therapeutic candidate target for neuromodulation of refractory gait disturbances in PD.</p> <p>Methods</p> <p>12 patients with idiopathic Parkinson's disease and refractory gait disturbances under best individual subthalamic nucleus stimulation and dopaminergic medication will be enroled into this double-blind 2 Ă 2 cross-over clinical trial. The treatment consists of two different stimulation settings using <it>(i) </it>conventional stimulation of the subthalamic nucleus [STNmono] and <it>(ii) </it>combined stimulation of distant electrode contacts located in the subthalamic nucleus and caudal border zone of STN and substantia nigra pars reticulata [STN+SNr]. The primary outcome measure is the change of the cumulative 'axial score' (UPDRS II items '13-15' and UPRDS III items '27-31') at three weeks of constant stimulation in either condition. Secondary outcome measures include specific scores on freezing of gait, balance function, quality of life, non-motor symptoms, and neuropsychiatric symptoms. The aim of the present trial is to investigate the efficacy and safety of a three week constant combined stimulation on [STN+SNr] compared to [STNmono]. The results will clarify, whether stimulation on nigral contacts additional to subthalamic stimulation will improve therapeutic response of otherwise refractory gait disturbances in PD.</p> <p>Trial registration</p> <p>The trial was registered with the clinical trials register of <url>http://www.clinicaltrials.gov</url> (<a href="http://www.clinicaltrials.gov/ct2/show/NCT01355835">NCT01355835</a>)</p
Conductance and density of states as the Kramers-Kronig dispersion relation
By applying the Kramers-Kronig dispersion relation to the transmission
amplitude a direct connection of the conductance with the density of states is
given in quantum scattering systems connected to two one-channel leads.
Using this method we show that in the Fano resonance the peak position of the
density of states is generally different from the position of the corresponding
conductance peak, whereas in the Breit-Wigner resonance those peak positions
coincide.
The lineshapes of the density of states are well described by a Lorentz type
in the both resonances.
These results are verified by another approach using a specific form of the
scattering matrix to describe scattering resonances.Comment: 9 pages, 4 figure
Dephasing and Measurement Efficiency via a Quantum Dot Detector
We study charge detection and controlled dephasing of a mesoscopic system via
a quantum dot detector (QDD), where the mesoscopic system and the QDD are
capacitively coupled. The QDD is considered to have coherent resonant
tunnelling via a single level. It is found that the dephasing rate is
proportional to the square of the conductance of the QDD for the Breit-Wigner
model, showing that the dephasing is completely different from the shot noise
of the detector. The measurement rate, on the other hand, shows a dip near the
resonance. Our findings are peculiar especially for a symmetric detector in the
following aspect: The dephasing rate is maximum at resonance of the QDD where
the detector conductance is insensitive to the charge state of the mesoscopic
system. As a result, the efficiency of the detector shows a dip and vanishes at
resonance, in contrast to the single-channel symmetric non-resonant detector
that has always a maximum efficiency. We find that this difference originates
from a very general property of the scattering matrix: The abrupt phase change
exists in the scattering amplitudes in the presence of the symmetry, which is
insensitive to the detector current but {\em stores} the information of the
quantum state of the mesoscopic system.Comment: 7 pages, 3 figure
Human Mas-related G protein-coupled receptors-X1 induce chemokine receptor 2 expression in rat dorsal root ganglia neurons and release of chemokine ligand 2 from the human LAD-2 mast cell line
Primate-specific Mas-related G protein-coupled receptors-X1 (MRGPR-X1) are highly enriched in dorsal root ganglia (DRG) neurons and induce acute pain. Herein, we analyzed effects of MRGPR-X1 on serum response factors (SRF) or nuclear factors of activated T cells (NFAT), which control expression of various markers of chronic pain. Using HEK293, DRG neuron-derived F11 cells and cultured rat DRG neurons recombinantly expressing human MRGPR-X1, we found activation of a SRF reporter gene construct and induction of the early growth response protein-1 via extracellular signal-regulated kinases-1/2 known to play a significant role in the development of inflammatory pain. Furthermore, we observed MRGPR-X1-induced up-regulation of the chemokine receptor 2 (CCR2) via NFAT, which is considered as a key event in the onset of neuropathic pain and, so far, has not yet been described for any endogenous neuropeptide. Up-regulation of CCR2 is often associated with increased release of its endogenous agonist chemokine ligand 2 (CCL2). We also found MRGPR-X1-promoted release of CCL2 in a human connective tissue mast cell line endogenously expressing MRGPR-X1. Thus, we provide first evidence to suggest that MRGPR-X1 induce expression of chronic pain markers in DRG neurons and propose a so far unidentified signaling circuit that enhances chemokine signaling by acting on two distinct yet functionally co-operating cell types. Given the important role of chemokine signaling in pain chronification, we propose that interruption of this signaling circuit might be a promising new strategy to alleviate chemokine-promoted pain
Phase fluctuations and the pseudogap in YBa2Cu3Ox
The thermodynamics of the superconducting transition is studied as a function
of doping using high-resolution expansivity data of YBa2Cu3Ox single crystals
and Monte-Carlo simulations of the anisotropic 3D-XY model. We directly show
that Tc of underdoped YBa2Cu3Ox is strongly suppressed from its mean-field
value (Tc-MF) by phase fluctuations of the superconducting order parameter. For
overdoped YBa2Cu3Ox fluctuation effects are greatly reduced and Tc ~ Tc-MF . We
find that Tc-MF exhibits a similar doping dependence as the pseudogap energy,
naturally suggesting that the pseudogap arises from phase-incoherent Cooper
pairing.Comment: 9 pages, 3 Figure
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