Proteasome Nuclear Import Mediated by Arc3 Can Influence Efficient DNA Damage Repair and Mitosis in Schizosaccharomyces Pombe

Proteasomes must efficiently remove their substrates throughout the cells in a timely manner as many of these proteins can be toxic. This study shows that proteasomes can do so efficiently because they are highly mobile. Furthermore this study uncovers that proteasome mobility requires functional Arc3, a subunit of the Arp2/3 complex

A POLICY-ORIENTED ETHNOGRAPHY OF THE WINTER BLUEFIN TUNA FISHERY IN BEAUFORT AND MOREHEAD CITY, NORTH CAROLINA

In the mid-1990s, sport fishermen from the Outer Banks of North Carolina stumbled upon a winter population of bluefin tuna in the shallow waters near shore. Each winter since then, fishermen have braved icy waters and frigid temperatures to capitalize on this resource. In their quest for a commercial share of the U.S. quota, these local fishermen have shown a unique interest in making their voices heard. They now play a significant role in the data collection and management of bluefin tuna, working side-by-side with scientists and forming a non-profit organization. This MP aims to document the cultural system of these fishermen and incorporate recommendations for more effective bluefin tuna management. In an effort to accomplish this goal I produced a policy-oriented ethnography that characterizes the social, economic and regulatory structure of the sport and commercial bluefin tuna fishery in Beaufort and Morehead City, North Carolina

Empirical move-on rules to inform fishing strategies: a New England case study

Increasingly, fisheries are being managed under catch quotas that are often further allocated to specific permit holders or sectors. At the same time, serious consideration is being given to the effects of discards on the health of target and non‐target species. Some quota systems have incorporated discard reduction as an objective by counting discards (including unmarketable fish) against the overall quota. The potential effect of the introduction of a quota system that includes accountability for discards on the fishing strategies employed by fishermen is enormous. This is particularly true for multispecies fisheries where healthy and depleted stocks co‐exist; resulting in a trip's catch being applied to very large and very small stock quotas simultaneously. Under such a scenario, fishermen have a strong incentive to minimize (i) catch of low‐quota or ‘choke’ stocks, (ii) regulatory discards due to minimum size limits and (iii) catch partially consumed by predators. ‘Move‐on’ rules (i.e. event‐triggered, targeted, temporary closure of part of a fishery when a catch or bycatch threshold is reached) have been employed in a variety of fisheries. However, their efficacy has been limited by a lack of empirical analyses underpinning the rules. Here, we examine the utility of spatiotemporal autocorrelation analyses to inform ‘move‐on’ rules to assist a sector of the New England Multispecies Fishery to reduce discards and maximize profits. We find the use of empirical move‐on rules could reduce catch of juvenile and choke stocks between 27 and 33%, and depredation events between 41 and 54%