The role of psychological resilience and aggression in injury prevention among martial arts athletes

IntroductionFor martial artists, the ability to manage reactions in the face of adversity and bounce back after a stressful event can have major impact on performance. The scope of the research is to investigate martial artists’ level of resilience and aggression (Go-ahead, Foul play, and Assertiveness factors), what is specific to athletes and who have suffered from moderate and/or severe injuries (in terms of resilience and three factors of aggression examined), and test the possibility that a psychological variable under investigation can predict athletes’ injury severity.Materials and methodsA total sample of 154 athletes from striking combat sports—SC (karate, taekwondo, kickboxing, and boxing), grappling combat sports—GC (judo and BJJ), and mixed martial artists (MMA) participated in the research. For assessing resilience, the Romanian adaptation of the Brief Resilience Scale (BRS) was used, and for aggression, the Romanian adaptation of Makarowski’s Sports Aggression Questionnaire was used. An injury report form was also created and applied to athletes.ResultsThe post-hoc tests (after running a single-factor multivariate analysis of variance) revealed significant differences for resilience and Foul (violent) play between the sports disciplines analyzed. A significant positive correlation was found between athletes’ injury severity and assertiveness in SC and between injury severity and resilience in GC. Through the t-test for independent samples, it was highlighted that the average value for Foul (violent) play is significantly higher in athletes who have suffered mild, moderate, and/or severe injuries compared with martial arts athletes who have suffered from only mild/minor injuries. A binomial logistic regression was also performed to verify to what extent Foul play predicts athletes’ injury severity.ConclusionA low level of Foul (violent) play is linked with a decreased likelihood of moderate and/or severe injuries in martial arts athletes. The study findings suggest that resilience, foul play, and assertiveness have an important role in injury prevention among martial artists

Reinforcing melt electrowritten elements with entangled multifibrillar strands for thin hydrogels with potential in bone resurfacing

Osteonecrosis of the femoral head (ONFH) is a disease that affects young adults in their thirties to fifties, representing the progressive destruction of the hip bone caused by deficient vascularization. As the condition slowly leads to complete collapse of the femoral head, the conventional solution is total hip arthroplasty. Thin scaffolds consisting of fiber-reinforced hydrogels could be used to regenerate the affected bone surface, coupled with hip resurfacing for less invasive approaches. Melt electrowriting (MEW) was used to produce polycaprolactone (PCL) reinforcing elements for thin scaffolds, with four mesh densities and highly tunable mechanical properties. The influence of the MEW process parameters on the PCL filaments’ morphology was investigated using Design of Experiments to optimize their fabrication and obtain tailorable structures with entangled fiber morphology for increased contact surface with the hydrogel component. Uniaxial tensile tests were performed to investigate the difference in tensile properties of the entangled design versus the aligned counterparts, including the exploration of the mesh size effect. The microstructure and microstructural changes of the entangled meshes at uniaxial tensile deformation were explored using micro-computed tomography. Plasma treated meshes were embedded in gelatin methacryloyl/alginate hydrogels, developing reinforced composite scaffolds with potential for bone surface reconstruction

Long-term follow-up of retropupillary iris-claw intraocular lens implantation: A retrospective analysis Cataract and refractive surgery

Background: The ideal intraocular lens in cases of aphakia without capsular support is debated. Choices include anterior chamber lenses, iris- or scleral-sutured lenses, and iris-claw lenses. Our aim was to report our long-term evaluation of the use of retropupillary implantation of the Artisan iris-claw intraocular lens (RPICIOL) in several aphakic conditions without capsular support. Methods: A retrospective analysis of consecutive 320 eyes of 320 patients (222 males and 98 females) without capsular support in which we performed RPICIOL implantation in post-traumatic aphakia (141 eyes, group 1), post-cataract surgery aphakia (122 eyes, group 2), and in cases in which penetrating keratoplasty was associated with vitrectomy (57 eyes, group 3). Either anterior or posterior vitrectomy procedures were performed with 20-, 23-, or 25-gauge techniques for different associated anterior or posterior segment indications. We reviewed the refractive outcome, anatomical outcome, long-term stability of the implants, and possible long-term complications. Results: The mean patient age was 59.7 years (range, 16-84 years) in group 1; 60.1 years (range, 14-76 years) in group 2; and 65.8 years (range, 25-71.5 years) in group 3. The mean follow-up time was 5.3 years (range, 1 month to 8 years). At the end of the follow-up period, the mean post-operative best-corrected LogMAR visual acuity was 0.6 (range, perception of light to 0.3) in group 1; 0.3 (range, 0.5-0.1) in group 2; and 0.6 (range, hand movement to 0.2) in group 3. Disenclavation of RPICIOLs occurred in three cases because of slippage of one of the iris-claw haptics and spontaneous complete posterior dislocation occurred in one case. One case presented with retinal detachment, and no cases of uveitis were observed. Eight cases complained of chronic dull pain, and severe iridodonesis was seen in five cases. One case of post-operative macular edema was observed without post-operative increase in the mean intraocular pressure. There was no statistically different change in the endothelial cell density (cells/mm2) at the end of the follow-up period. Conclusions: RPICIOL for secondary implantations is a valid alternative strategy to scleral-fixated or angle-supported IOL implantation

High Efficacy on the Death of Breast Cancer Cells Using SPMHT with Magnetite Cyclodextrins Nanobioconjugates

In this study, we present the experimental results obtained in vitro on the human breast adenocarcinoma cell line (MCF-7) by applying superparamagnetic hyperthermia (SPMHT) using novel Fe3O4-PAA–(HP-γ-CDs) (PAA is polyacrylic acid and HP-γ-CDs is hydroxypropyl gamma-cyclodextrins) nanobioconjugates previously obtained by us. In the in vitro SPMHT experiments, we used concentrations of 1, 5 and 10 mg/mL of Fe3O4 ferrimagnetic nanoparticles from Fe3O4-PAA–(HP-γ-CDs) nanobioconjugates suspended in culture media containing 1 × 105 MCF-7 human breast adenocarcinoma cells. The harmonic alternating magnetic field used in the in vitro experiments that did not affect cell viability was found to be optimal in the range of 160–378 Gs and at a frequency of 312.2 kHz. The appropriate duration of the therapy was 30 min. After applying SPMHT with these nanobioconjugates under the above conditions, MCF-7 cancer cells died out in a very high percentage, of until 95.11%. Moreover, we studied the field up to which magnetic hyperthermia can be safely applied without cellular toxicity, and found a new upper biological limit H × f ~9.5 × 109 A/m⋅Hz (H is the amplitude and f is the frequency of the alternating magnetic field) to safely apply the magnetic field in vitro in the case of MCF-7 cells; the value was twice as high compared to the currently known value. This is a major advantage for magnetic hyperthermia in vitro and in vivo, because it allows one to achieve a therapy temperature of 43 °C safely in a much shorter time without affecting healthy cells. At the same time, using the new biological limit for a magnetic field, the concentration of magnetic nanoparticles in magnetic hyperthermia can be greatly reduced, obtaining the same hyperthermic effect, while at the same time, reducing cellular toxicity. This new limit of the magnetic field was tested by us in vitro with very good results, without the cell viability decreasing below ~90%

Endoscopic cyclophotocoagulation in refractory glaucoma after osteo-odonto-keratoprosthesis in Stevens-Johnson syndrome: a case report

To report successful treatment of refractive glaucoma in a patient submitted to osteo-odonto-keratoprosthesis surgery for Stevens-Johnson syndrome

MODIFICATION of ADJUSTABLE MACULAR BUCKLING with 29-G CHANDELIER LIGHT for OPTIMAL POSITIONING in HIGHLY MYOPIC EYES with MACULAR HOLE

Purpose: To evaluate the efficacy of the modification of Adjustable Macular Buckling device in the treatment of myopic macular hole retinal detachment with posterior staphyloma. Methods: Four consecutive patients suffering from myopic macular detachment with macular hole were treated using the macular buckling procedure. An Adjustable Macular Buckling device was used in all four cases and was modified using a 29-gauge optical fiber to illuminate its macular plate. Results: Optical coherence tomography showed successful retinal reattachment and closure of the macular hole after the buckling procedure. The macular plate of the buckling device was properly positioned in all four patients. No complications were observed. Conclusion: The modification of the macular buckling device improves the accuracy of its positioning by illuminating its macular plate

Cystoid macular edema after pars plana vitrectomy for idiopathic epiretinal membrane

Background To evaluate the incidence of cystoid macular edema (CME) after 23-gauge pars plana vitrectomy (PPV) with or without combined cataract surgery for the treatment of idiopathic epiretinal membrane (ERM). Methods Retrospective, non-comparative, interventional case series. Data included patient age, indication for surgery, and intra- and post-operative complications. The follow-up lasted 1 year. Best-corrected visual acuity (BCVA logMAR), central foveal thickness (CFT micron-μ) and the incidence of intra-retinal cysts were evaluated.CME was defined as post-operative observation of intra-retinal cysts at optical coherence tomography, preventing improvement or causing reduction of BCVA when compared to the pre-operative value. Statistical analysis was performed to identify the risk factors of CME. Results Two hundred and forty two eyes of 242 patients underwent PPV for the treatment of idiopathic ERM. Statistical analysis showed that the presence of preoperative intra-retinal cysts were associated with persistent CME following surgery (odds ratio 3.89; 95%CI: 1.63-9.28, P = 0.0004). However, postoperative CME occurred in 10 % of eyes that did not show preoperative CME. In addition, there was a significant correlation between the baseline value of CFT and the values of CFT at each time point during the follow up (p < 0.0001), with greater values of the pre-operative thickness correlating to greater values of post-operative thickness. Conclusions Persistent or new CME following surgery for idiopathic ERM are frequently identified after PPV for ERM. The statistical results of the current study suggest that intraretinal cysts and increased preoperative CFT are associated with reduced visual acuity after surgery

Simultaneous correction of post-traumatic aphakia and aniridia with the use of artificial iris and IOL implantation

Abstract BACKGROUND: Combined post-traumatic aniridia and aphakia demand extensive and complex reconstructive surgery. We present our approach for simultaneous correction of this surgical situation with the use of the ArtificialIris (Dr. Schmidt Intraocularlinsen GmbH, Germany) with a foldable acrylic IOL Lentis L-313 (Oculentis, GmbH, Germany) sutured to its surface. The novelty (our first operation was on June 2010) of this surgical technique is based on the combined use of foldable (with closed haptics) IOL and Artificialiris to correct post-traumatic aniridia and aphakia. METHODS: Four consecutive cases of combined post-traumatic lesions of iris and lens, corrected with complex device ArtificialIris and foldable IOL. In two cases, the compound implant was sutured to the sclera in sulcus during the penetrating keratoplasty; in another case, it was positioned through a corneal incision of about 5.0 mm with transscleral fixation, and in one patient with preserved capsular support and possibility of IOL in-the-bag implantation the ArtificialIris was placed in sulcus sutureless through a clear corneal tunnel. RESULTS: Maximal follow-up was 6 months. The complex device was placed firmly fixed within the sulcus, including in the eye implanted without sutures, and showed a stable and centered position without any tilt or torque. CONCLUSION: Management of post-traumatic aniridia combined with aphakia by haptic fixation of a foldable acrylic IOL on a foldable iris prosthesis appears to be a promising approach which gives the surgeon the possibility to correct a complex lesion with one procedure, which is less traumatic and faster. Existence of foldable materials, both iris and IOL, permits relatively small corneal incisions (4.0-5.0 mm). Moreover, the custom-tailored iris prosthesis gives a perfect aesthetic result