Burden of Diverticulosis and Diverticular Disease

The term “diverticular disease” (DD) covers a variety of conditions associated with the presence of colonic diverticula, herniations of the colonic mucosa through the muscular membrane and the clinical manifestations associated with their inflammation. DD represents one of the most common gastrointestinal diseases in the Western industrialized countries, and the prevalence tends to increase with increasing age, thus showing an increasing incidence in younger patients. Diverticulosis remains clinically asymptomatic in most patients during their lifetime, but up to 25% of them develop symptoms and up to a quarter experience at least one episode of acute diverticulitis (AD), an acute inflammatory process of diverticula with various complications (e.g., perforation, obstruction, fistula, etc.) described in 15–20% of cases. AD incidence has been increasing in the last few decades, representing one of the main reasons for hospitalization for DD patients and consequently one of the factors that most impact the disease burden. The Global Burden of Disease in 2019 assessed DD as the leading cause of death in the group “other digestive diseases”, which includes various codes of International Statistical Classification of Diseases and Related Health Problems, tenth Revision (ICD-10). Despite the significant epidemiological burden and the consequent impact on health services of this condition, there are no major studies in European countries that evaluate its impact

Impact of diverticular inflammation and complication assessment classification on the burden of medical therapies in preventing diverticular disease complications in Italy

Background: Several treatments are currently advised to manage diverticular disease (DD) patients, but their impact on the burden of the disease is unknown. Our aim was to assess the economic analysis of using the recent Diverticular Inflammation and Complication Assessment (DICA) endoscopic classification on the burden of medical therapies prescribed in preventing DD complications occurrence in Italy. Methods: We assessed retrospectively the cost/year of treatments in estimated DICA 1, DICA 2 and DICA 3 population. Analysis of diverticulosis prevalence was estimated according to data population provided by Italian Institute of Statistics (ISTAT). Cost of treatments calculated according to data on drugs' consumption collected during the DICA study. Results: We estimated that > 8 million of Italian people > 60 years may have diverticulosis, and that about 75% of diverticular population are on DICA 1, about 30% on DICA 2, and about 13% on DICA 3. We estimated that > 387 million of euros could be spent in DICA 1 population, > 203 million of euros in DICA 2 population, and > 88 million of euros in DICA 3 population. Since medical treatments did not show any significant advantage when treating DICA 1 and DICA 3 people in terms of prevention of acute diverticulitis occurrence/recurrence and surgery occurrence, we can estimated that > 475 million of euros could be spent in Italy without any significant benefit in preventing DD complications occurrence. Conclusions: DICA endoscopic classification may have a significant impact on the burden of DD in Italy, because it helps to select DD people who effectively need treatments in terms of prevention of acute diverticulitis occurrence/recurrence and surgery occurrence

A Walkable Urban Environment to Prevent Chronic Diseases and Improve Wellbeing, an Experience of Urban Health in the Local Health Unit Roma 1

Cities play a vital role in promoting health, as most of the world’s population lives in urban areas. Urbanization and city planning are both factors that must be considered to improve the health of communities. Walkability is a measure of how friendly an area is to walk. The Walking Suitability Index of the Territory (T-WSI) measures the pedestrian viability of the streets of a environmental islands. It includes 12 indicators, distributed into four categories: practicability, safety, urbanity, pleasantness. The goal of this study is to establish a model of connection between universities, local authorities, and health institutions to improve the walkability of urban areas. Five Environmental Islands were identified in the Municipality of Roma Capitale. First step concerned multidisciplinary training, sharing the goal between professionals in both the health and non-health fields. The theoretical acquisition, for Public Health personnel, on the use of the “walkability” assessment tool T-WSI was concretized by applying the assessment in training inspections. The on-site measurements showed that the main critical issues in terms of unfavorable factors for walking are the obstacles on the sidewalks, concerning the safety of pedestrian crossings and protection from vehicular speed. Measurement was associated with a characterization based on census data, obtained from satellite imagery. It is important to develop tools that are easy to apply and that can be easily used, also by health personnel. This is necessary in the light of recent developments in the Italian regulatory framework, and international guidelines, toward a growing integration of professional skills with the common objective of Urban Health. © 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG

Urban Health and Social Marginality: Perceived Health Status and Interaction with Healthcare Professionals of a Hard-to-Reach Community Living in a Suburban Area of Rome (Italy)

The study reports an urban health investigation conducted in Bastogi, an outskirt of Rome (Italy) characterised by social marginalization and deprivation. Our aim was to analyse the health perception, health-related behaviours, and interaction with healthcare professionals of the inhabitants of Bastogi compared to the population living in the area of the same local health unit (ASL). The Progresses of Health Authorities for Health in Italy questionnaire (PASSI) was administered to a sample of 210 inhabitants of Bastogi. Data were analysed and compared to those of the ASL collected in 2017–2018. The socio-economic indicators showed an overall worse condition for the inhabitants of Bastogi, with a significantly higher proportion of foreign and unemployed residents and a lower educational level compared to the ASL. Significant differences in the prevalence of non-communicable diseases, mental health complaints, and participation in prevention strategies, including cancer screening, were found. The questionnaire showed a lower help-seeking behaviour and a lack of reliance on health professionals in Bastogi inhabitants. Our findings highlight how social determinants produce health inequities and barriers to accessing healthcare. The difficulties of conducting quantitative research in complex and hard-to-reach contexts, characterized by high social vulnerability, are outlined

The "DICA" endoscopic classification for diverticular disease of the colon shows a significant interobserver agreement among community endoscopists

BACKGROUND AND AIM: An endoscopic classification of Diverticular Disease (DD), called DICA (Diverticular Inflammation and Complication Assessment) is currently available. It scores severity of the disease as DICA 1, DICA 2 and DICA 3. Our aim was to assess the agreement levels for this classification among an endoscopist community setting. METHODS: A total of 66 endoscopists independently scored a set of DD endoscopic videos. The percentages of overall agreement on the DICA score and a free-marginal multirater kappa (κ) coefficient were reported as statistical measures of the inter-rater agreement. RESULTS: The overall agreement levels were: 70.2% for DICA 1, 70.5% for DICA 2, 81.3% for DICA 3. The free marginal κ was: 0.553 for DICA 1, 0.558 for DICA 2, 0.719 for DICA 3. The agreement levels among the expert group were: 78.8% for DICA 1, 80.2% for DICA 2, 88.5% for DICA 3. The free marginal κ among the expert group were: 0.682 for DICA 1, 0.712 for DICA 2, 0.828 for DICA 3. The agreement of expert raters on the single item of the DICA classification was superior to the agreement of the overall group. CONCLUSIONS: The overall inter-rater agreement for DICA score in this study ranges from moderate to good, with a significant improvement in the expert subgroup of raters. Diverticular Inflammation and Complication Assessment is a simple and reproducible endoscopic scoring system

The “dica” endoscopic classification for diverticular disease of the colon shows a significant interobserver agreement among community endoscopists

BACKGROUND AND AIM: An endoscopic classification of Diverticular Disease (DD), called DICA (Diverticular Inflammation and Complication Assessment) is currently available. It scores severity of the disease as DICA 1, DICA 2 and DICA 3. Our aim was to assess the agreement levels for this classification among an endoscopist community setting. METHODS: A total of 66 endoscopists independently scored a set of DD endoscopic videos. The percentages of overall agreement on the DICA score and a free-marginal multirater kappa (κ) coefficient were reported as statistical measures of the inter-rater agreement. RESULTS: The overall agreement levels were: 70.2% for DICA 1, 70.5% for DICA 2, 81.3% for DICA 3. The free marginal κ was: 0.553 for DICA 1, 0.558 for DICA 2, 0.719 for DICA 3. The agreement levels among the expert group were: 78.8% for DICA 1, 80.2% for DICA 2, 88.5% for DICA 3. The free marginal κ among the expert group were: 0.682 for DICA 1, 0.712 for DICA 2, 0.828 for DICA 3. The agreement of expert raters on the single item of the DICA classification was superior to the agreement of the overall group. CONCLUSIONS: The overall inter-rater agreement for DICA score in this study ranges from moderate to good, with a significant improvement in the expert subgroup of raters. Diverticular Inflammation and Complication Assessment is a simple and reproducible endoscopic scoring system

Adapted Physical Activity for the Promotion of Health and the Prevention of Multifactorial Chronic Diseases: the Erice Charter

The Erice Charter was unanimously approved at the conclusion of the 47th Residential Course "Adapted Physical Activity in Sport, Wellness and Fitness: New Challenges for Prevention and Health Promotion", held on 20-24 April 2015 in Erice, Italy, at the "Ettore Majorana" Foundation and Centre for Scientific Culture, and promoted by the International School of Epidemiology and Preventive Medicine "G. D'Alessandro" and the Study Group on Movement Sciences for Health of the Italian Society of Hygiene, Preventive Medicine and Public Health. After an intense discussion the participants identified the main points associated with the relevance of physical activity for Public Health, claiming the pivotal role of the Department of Prevention in coordinating and managing preventive actions. The participants underlined the importance of the physicians specialized in Hygiene, Preventive Medicine and Public Health. The contribution of other operators such as physicians specialized in Sport Medicine was stressed. Further, the holders of the new degree in Human Movement and Sport Sciences were considered fundamental contributors for the performance of physical activity and their presence was seen as a promising opportunity for the Departments of Prevention. Primary prevention based on recreational physical activities should become easily accessible for the population, avoiding obstacles such as certification steps or complex bureaucracy. The Sport Doctor is recognized as the principal referent for preliminary physical evaluation and clinical monitoring in secondary and tertiary prevention actions based on adapted physical activities. Developing research in the field is essential as well as implementing higher education on physical activity management in Schools of Public Health