Application of semiconductor industry cleaning technologies for Genesis sample collectors

Genesis array collectors recovered after the sub-nominal landing have been exposed to particulate and molecular contamination. In this study, semiconductor industry based cleaning technologies are being evaluated for their efficacy in contaminant removal

2015 Lancet Commission on Health and Climate Change: Briefing for health policy-makers and health professionals

The 2015 Lancet Commission on Health and Climate Change concludes that responding to climate change could be the greatest global health opportunity of the twenty-first century. Many solutions to climate change offer significant health ‘co-benefits’, reducing healthcare costs for often over-burdened health systems and improving economic productivity. Alongside reducing emissions, climate change adaptation is essential to protect health. Decades-long lag in the climate system means that we are already ‘locked-in’ to many years of warming, and the associated impacts, even if emissions drop sharply. Climate change affects the world’s poorest countries earliest and most severely, despite them being least responsible. Wealthier countries therefore have a responsibility to support poor countries’ responses

Indirect age- and sex-standardisation of COVID-19-related mortality rates for the prison population of England and Wales

This paper estimates a standardised mortality ratio (SMR) for death due to COVID-19 among people in prisons in England and Wales between 1 March 2020 and 26 February 2021. Over this period, prisons in England and Wales reported 121 deaths related to COVID-19. The SMR is 3.33 (95% C.I. 2.77–3.98), meaning there were 3.33 times more deaths among people in prisons than expected given the age and sex of the population

Incorporating practitioner knowledge to test and improve a new conceptual framework for healthy urban design and planning

There are increasing arguments for bridging diverse knowledges and co-producing new knowledge between researchers, professional communities and citizens to create health-promoting built environments. The new THRIVES Framework (Towards Healthy uRbanism: InclusiVe, Equitable, Sustainable) echoes the call that healthy urbanism processes should be participatory and this principle informed the development of the Framework itself, which involved several stages of informal and formal testing with stakeholders, through a process of action research and ‘extended peer review’. Formal feedback about the design of the preliminary Framework and its implementation in built environment practice was gathered through a participatory workshop with 26 built environment and public health professionals in January 2020. Participants were encouraged to share their knowledge, ask questions, critique and provide recommendations. Overall, participants were supportive of the conceptual messages of the THRIVES Framework and more critical of the visual design of the preliminary version. They also questioned whether further resources would be required to implement the Framework. This research created a forum for stakeholders, who may typically be outside the research process, to shape the development of a conceptual framework for healthy urbanism. Further research and collaboration will create resources to bridge the gap between this new conceptualisation and practice

Are there any stable magnetic fields in barotropic stars?

We construct barotropic stellar equilibria, containing magnetic fields with both poloidal and toroidal field components. We extend earlier results by exploring the effect of different magnetic field and current distributions. Our results suggest that the boundary treatment plays a major role in whether the poloidal or toroidal field component is globally dominant. Using time evolutions we provide the first stability test for mixed poloidal-toroidal fields in barotropic stars, finding that all these fields suffer instabilities due to one of the field components: these are localised around the pole for toroidal-dominated equilibria and in the closed-field line region for poloidal-dominated equilibria. Rotation provides only partial stabilisation. There appears to be very limited scope for the existence of stable magnetic fields in barotropic stars. We discuss what additional physics from real stars may allow for stable fields.Comment: 16 pages, 11 figures. Some minor revision from v1, including a new figure; results unchanged. Now published in MNRA

What makes the health system tick?

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Automated and semi-automated contact tracing: Protocol for a rapid review of available evidence and current challenges to inform the control of COVID-19

Abstract Introduction Traditional approaches to case-finding, case isolation, and contact tracing methods have so far proved insufficient on their own to prevent the development of local epidemics of COVID-19 in many high-income countries despite relatively advanced public health systems. As a result, many governments have resorted to widespread social distancing measures and mass quarantines (‘lock-downs’) to reduce transmission and to prevent healthcare systems from being overwhelmed. However, such measures impose heavy human and societal costs. Automated or semi-automated digital contact tracing, in conjunction with scaled-up community testing, has been proposed as a key part of exit strategies from lockdowns. However, the effectiveness of these approaches to contact tracing is unclear, and to be effective, trusted, and widely adopted such technology must overcome several challenges. Methods and analysis We will perform a rapid systematic review to assess the effectiveness of automated and semi-automated digital tools for contact tracing, and identify key considerations for successful implementation, to inform the control of COVID-19. We will search PubMed, EMBASE, EBSCO Medical COVID information portal, OVID Global Health, Cochrane Library, medRxiv, BioRxiv, and arXiv for peer-reviewed and pre-print papers on automated or semi-automated digital tools for contact tracing of COVID-19, another respiratory disease with pandemic potential (limited to SARS, MERS, or pandemic influenza), or Ebola, in human populations. Studies will be eligible if published in English between 1 January 2000 and 14 April 2020. We will synthesise study findings narratively and will consider meta-analysis if ≥ 3 suitable studies with comparable interventions and outcomes are available. Ethics and dissemination Ethical approval is not required for this review. We plan to disseminate findings via pre-print, journal publication, through social media and web-based platforms and through direct stakeholder engagement

Air Pollution (Particulate Matter) Exposure and Associations with Depression, Anxiety, Bipolar, Psychosis and Suicide Risk: A Systematic Review and Meta-Analysis

BACKGROUND: Particulate air pollution's physical health effects are well known, but associations between particulate matter (PM) exposure and mental illness have not yet been established. However, there is increasing interest in emerging evidence supporting a possible etiological link. OBJECTIVES: This systematic review aims to provide a comprehensive overview and synthesis of the epidemiological literature to date by investigating quantitative associations between PM and multiple adverse mental health outcomes (depression, anxiety, bipolar disorder, psychosis, or suicide). METHODS: We undertook a systematic review and meta-analysis. We searched Medline, PsycINFO, and EMBASE from January 1974 to September 2017 for English-language human observational studies reporting quantitative associations between exposure to PM 6   months ) PM 2.5 exposure and depression ( n = 5 studies), the pooled odds ratio was 1.102 per 10 - μ g / m 3 PM 2.5 increase (95% CI: 1.023, 1.189; I 2 = 0.00 % ). Two of the included studies investigating associations between long-term PM 2.5 exposure and anxiety also reported statistically significant positive associations, and we found a statistically significant association between short-term PM 10 exposure and suicide in meta-analysis at a 0-2 d cumulative exposure lag. DISCUSSION: Our findings support the hypothesis of an association between long-term PM 2.5 exposure and depression, as well as supporting hypotheses of possible associations between long-term PM 2.5 exposure and anxiety and between short-term PM 10 exposure and suicide. The limited literature and methodological challenges in this field, including heterogeneous outcome definitions, exposure assessment, and residual confounding, suggest further high-quality studies are warranted to investigate potentially causal associations between air pollution and poor mental health