13 research outputs found

    The Grizzly, April 12, 2001

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    Airband 2001: \u27Case to the Ex\u27 Claims Victory • CAB, RHA, USGA and Class Officer Elections to be Held • Religion Forum Engages Students in Faith-based Discussion • The Big Test: Redefining the SATs • Opinions: Dispelling the Rumors: National Greeks Respond; Questioning the National Greek Approval Process; Purpose of Nationals: To Build up, not Destroy, Existing Greek Life on Campus; Why I Wanted to Bring Tri Sigma to Ursinus College; Tri Sigma Sorority Members Respond to Controversy; Phi Kappa Sigma Fraternity: The Brotherhood of Gentlemen; Why AOL Instant Messenger Will be the Demise of Society • Berman Exhibit \u27Zelda: By Herself\u27 on Display Until Apr. 19 • Women\u27s LAX Remains Undefeated, in First Placehttps://digitalcommons.ursinus.edu/grizzlynews/1488/thumbnail.jp

    The Grizzly, September 5, 2000

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    Freshman Clustering: Ideal Living or Mission Impossible? • 2 Major Additions Make Debut this Fall • UC Online Generates Digital Excitement • Fitness House Hopes to Spark Student Interest in Athletics • Fountain Near Pfahler in the Works for Next Summer • Summer in Cambridge, Paris Unforgettable • New Professor Added in Computer Science Department • Opinion: Is Cheerleading a Sport??; Campaign 2000: Eye on Education; The Lesson is in the Language: The Republican Educational Plan • Summer Concert Review: Dave Matthews Band Spectacular at the Vet • International Film Festival Set to Begin at UC • Women\u27s Soccer Invincible at Invitational • Men Win Opener, Drop Heartbreaker • Uphill Battle Ahead for Cross Country Squad • Volleyball Team Dlgs out a Win in Virginia • Football Ranked Second in Conference Preseason Poll • Athlete of the Week: Krista Bailey • Meningitis: What UC Students Need to Know • UC Sophomore Reflects on Horrors of Freshman Fifteen • Rough Start for Bears\u27 Field Hockeyhttps://digitalcommons.ursinus.edu/grizzlynews/1470/thumbnail.jp

    The Grizzly, November 2, 2000

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    Students Rally to End Sexual Assault, Violence • Homecoming Case Closed, all Charges Dropped • Scuffle at Duryea Still Being Investigated • UC House of Horrors: Children Enjoy Ghoulish Experience • Operation Christmas Child • Goldstein Appointed Hillel Director • Study Abroad in London, Florence Next Fall • Annual Halloween Decorating Contest Winners Announced • Opinions: Where\u27s the Rush? Shortening of Rushing Activities has Some Greeks Angry, Upset; Up in Smoke: Non-smokers Fed up with UC Students Lighting up; Gore Does More to Combat Hate Crimes; Are we too old for Halloween?; A Vote for Al Gore is a Vote for our Future; Don\u27t Waste Your Vote on Majority Party Candidates, Elect Nader Nov. 7; Amidst Campus Safety Concerns, are IDs the Answer?; Rewards of Mideast Outweigh Risks for one UC Student • Students Make MTV Debut on \u27Total Request Live\u27 • Gone with the Wind: Bears Drop Heartbreaker to Mules on Blustery Day • It\u27s Madness!: Hoops Squad Scores Big with Annual Slam-dunk, Kick-off Festivities • Volleyball Drops Season Finale to Conference Rival • Men\u27s Soccer Falls to Fords • Men\u27s Lacrosse Gears up for Spring Season • Breast Cancer: What College Students Need to Know • Annual Health Fair Acquires new Name, Attitude • Tips for Female Lifters to Make it big in the Weight Room • Bears Field Hockey Rocks Rider, Finishes Season with Patriot League Win • XC Takes on WMC Course at Conference Champshttps://digitalcommons.ursinus.edu/grizzlynews/1477/thumbnail.jp

    Small Scattered Fragments Do Not a Dwarf Make: Biological and Archaeological Data Indicate that Prehistoric Inhabitants of Palau Were Normal Sized

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    Current archaeological evidence from Palau in western Micronesia indicates that the archipelago was settled around 3000–3300 BP by normal sized populations; contrary to recent claims, they did not succumb to insular dwarfism

    Intelligent resolution: Integrating Cryo-EM with AI-driven multi-resolution simulations to observe the severe acute respiratory syndrome coronavirus-2 replication-transcription machinery in action

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    The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) replication transcription complex (RTC) is a multi-domain protein responsible for replicating and transcribing the viral mRNA inside a human cell. Attacking RTC function with pharmaceutical compounds is a pathway to treating COVID-19. Conventional tools, e.g. cryo-electron microscopy and all-atom molecular dynamics (AAMD), do not provide sufficiently high resolution or timescale to capture important dynamics of this molecular machine. Consequently, we develop an innovative workflow that bridges the gap between these resolutions, using mesoscale fluctuating finite element analysis (FFEA) continuum simulations and a hierarchy of AI-methods that continually learn and infer features for maintaining consistency between AAMD and FFEA simulations. We leverage a multi-site distributed workflow manager to orchestrate AI, FFEA, and AAMD jobs, providing optimal resource utilization across HPC centers. Our study provides unprecedented access to study the SARS-CoV-2 RTC machinery, while providing general capability for AI-enabled multi-resolution simulations at scale
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