Quantification of mixture composition, liquid-phase fraction and temperature in transcritical sprays

How do fuel and air mix, if a liquid fuel is injected into an environment featuring pressure and temperature that exceed the critical pressure and the critical temperature of the fuel? It is subject of current discussion on whether and if so when, the fuel/air-mixture becomes supercritical or not. We here report experimental data comprising three mixture properties that are relevant for the current debate, all spatially and temporally resolved throughout the spray and injection event: The overall composition of the fuel/air-mixture, the liquid fraction of the fuel/air-mixture, and the temperature of the liquid phase. To this end, we applied Raman spectroscopy and gave special attention to the signature of the Raman OH-band of ethanol, which we used as fuel. Its signature is connected to the development of a hydrogen bonded network between the ethanol molecules and thus extremely sensitive to thermodynamic state and temperature. Measurements were carried out in a high-pressure, high-temperature combustion vessel in a pressure range of 3−8 MPa and a temperature range of 573−923 K. For the highest set temperature we found ethanol in liquid-like mixtures that exceeded the mixture critical temperature. This is an indication of the existence of a single-phase mixing path

Collaborative Business Process Management - A Literature-based Analysis of Methods for Supporting Model Understandability

Due to the growing amount of cooperative business scenarios, collaborative Business Process Management (cBPM) has emerged. The increased number of stakeholders with minor expertise in process modeling leads to a high relevance of model understandability in cBPM contexts. Despite extensive works in the research fields of cBPM and model understandability in BPM, there is no analysis and comprehensive overview of methods supporting process model understandability in cBPM scenarios. To address this research gap, this paper presents the results of a literature review. The paper identifies concepts for supporting model understandability in BPM, provides an overview of methods implementing these concepts, and discusses the methods’ applicability in cBPM. The four concepts process model transformation, process model visualization, process model description, and modeling support are introduced. Subsequently, 69 methods are classified and discussed in the context of cBPM. Results contribute to revealing existing academic voids and can guide practitioners in cBPM scenarios

Die neue EU-Zuckermarktordnung und ihre regionalwirtschaftlichen Folgen in der Bundesrepublik Deutschland seit 2005: Forschungsprojekt im Auftrag der Hans-Böckler-Stiftung

Die neue Zuckermarktordnung hat in der zweiten Hälfte des zurückliegenden Jahrzehnts innerhalb der EU für die Wertschöpfungskette der Zuckerherstellung tief greifende Veränderungen nach sich gezogen. Landwirtschaft und Industrie, Arbeitgeber wie Arbeitnehmer mussten sich mit knappen Vorlaufzeiten den Herausforderungen stark veränderter Rahmenbedingungen stellen, die mit klaren Einschnitten in die Rübenanbauflächen und die industriellen Verarbeitungskapazitäten einhergingen. Die Studie zeichnet diese Entwicklungen chronologisch und in den Folgewirkungen nach. Sie untersucht innerhalb der Bundesrepublik Deutschland anhand von einzelnen Fallstudien die regionalen bzw. lokalen Auswirkungen, die sich mit der weiteren Konzentration der Produktionsstandorte vor allem da ergeben haben, wo es zur Stilllegung von Werken gekommen ist. In einem weiteren Schritt wird mit Hilfe der Entwicklungen im Rheinland beispielhaft aufgezeigt, welche Veränderungen für Landwirte, Unternehmen, Arbeitnehmer seit 2006 aus der neuen Zuckermarktordnung resultieren. Dies führt zur Grundsatzfrage: Wie hat sich das neue Regelwerk im wirtschaftlichen Alltag der Betroffenen bewährt? Die Studie bewertet Erfolg und Misserfolg der neuen Zuckermarktordnung vor dem Hintergrund der ursprünglichen Zielsetzungen der EU - Kommission. Sie stellt die Frage nach der Zukunft der heimischen Zuckerindustrie und der dortigen Arbeitsplätze unter den Rahmenbedingungen eines weltweit offenen Wettbewerbs

Influence of Sodium Chloride on the Formation and Dissociation Behavior of CO2 Gas Hydrates

We present an experimental study on the formation and dissociation characteristics of carbon dioxide (CO2) gas hydrates using Raman spectroscopy. The CO2 hydrates were formed from sodium chloride/water solutions with salinities of 0–10 wt %, which were pressurized with liquid CO2 in a stirred vessel at 6 MPa and a subcooling of 9.5 K. The formation of the CO2 hydrate resulted in a hydrate gel where the solid hydrate can be considered as the continuous phase that includes small amounts of a dispersed liquid water-rich phase that has not been converted to hydrate. During the hydrate formation process we quantified the fraction of solid hydrate, xH, and the fraction of the dispersed liquid water-rich phase, xL, from the signature of the hydroxyl (OH)-stretching vibration of the hydrate gel. We found that the fraction of hydrate xH contained in the hydrate gel linearly depends on the salinity of the initial liquid water-rich phase. In addition, the ratio of CO2 and water was analyzed in the liquid water-rich phase before hydrate formation, in the hydrate gel during growth and dissociation, and after its complete dissociation again in the liquid water-rich phase. We observed a supersaturation of CO2 in the water-rich phase after complete dissociation of the hydrate gel and were able to show that the excess CO2 exists as dispersed micro- or nanoscale liquid droplets in the liquid water-rich phase. These residual nano- and microdroplets could be a possible explanation for the so-called memory effect

A Raman technique applicable for the analysis of the working principle of promoters and inhibitors of gas hydrate formation

We report a Raman technique applicable for the in situ analysis of the development of hydrogen bonds in the liquid water‐rich phase just before the onset of gas hydrate formation. Herewith, the phase transition as well as the working principle of hydrate formation inhibitors and promoters can be analyzed

Mechanism development and modelling of tropospheric multiphase halogen chemistry : The CAPRAM Halogen Module 2.0 (HM2)

A new detailed multiphase halogen mechanism, the CAPRAM Halogen Module 2.0 (HM2), has been developed and coupled to the multiphase chemistry mechanism RACM-MIM2ext/CAPRAM 3.0n. The overall mechanism comprises 1,705 reactions including 595 reactions of the HM2. Halogen chemistry box model studies have been, for the first time, performed with a non-permanent cloud scenario for pristine open ocean regions in mid-latitudes. Moreover, detailed time-resolved reaction flux analysis has been used to investigate the multiphase halogen reaction cycles in more detail. Clouds significantly change the multiphase halogen chemical system and new reaction cycles are proposed for in-cloud conditions. While most gas phase concentrations are decreased for chlorine and iodine species, they are increased for bromine. Flux analyses determined the relative contributions of the methylene dihalides CH2IX (X = Cl, Br, I) as the main I atom source with a contribution of about 80 % to the total iodocarbon sources. Furthermore, HOI was confirmed to be important for chlorine activation. It is shown that 25 % of the ozone loss can be attributed to halogens. VOC oxidation by halogens is important as halogens account for about 20 % of the methane oxidation and up to 80 % of the oxidation of other VOCs. In other cases, enhanced VOC and VOC oxidation product concentration levels were found. For example, 15 % of the methyl peroxyl radicals are formed after the reaction of chlorine atoms with methane or methyl hydroperoxide. In the aqueous phase, changes in the oxidation of organics do only occur for highly oxidised organics without a C-H bond. For example, over 80 % of oxalic acid are oxidised by electron transfer with Cl2− in deliquescent particles during non-cloud periods

Olfactory Performance as an Indicator for Protective Treatment Effects in an Animal Model of Neurodegeneration

Background: Neurodegenerative diseases are often accompanied by olfactory deficits. Here we use a rare neurovisceral lipid storage disorder, Niemann–Pick disease C1 (NPC1), to illustrate disease-specific dynamics of olfactory dysfunction and its reaction upon therapy. Previous findings in a transgenic mouse model (NPC1-/-) showed severe morphological and electrophysiological alterations of the olfactory epithelium (OE) and the olfactory bulb (OB) that ameliorated under therapy with combined 2-hydroxypropyl-ß-cyclodextrin (HPßCD)/allopregnanolone/miglustat or HPßCD alone.Methods: A buried pellet test was conducted to assess olfactory performance. qPCR for olfactory key markers and several olfactory receptors was applied to determine if their expression was changed under treatment conditions. In order to investigate the cell dynamics of the OB, we determined proliferative and apoptotic activities using a bromodeoxyuridine (BrdU) protocol and caspase-3 (cas-3) activity. Further, we performed immunohistochemistry and western blotting for microglia (Iba1), astroglia (GFAP) and tyrosine hydroxylase (TH).Results: The buried pellet test revealed a significant olfactory deterioration in NPC1-/- mice, which reverted to normal levels after treatment. At the OE level, mRNA for olfactory markers showed no changes; the mRNA level of classical olfactory receptor (ORs) was unaltered, that of unique ORs was reduced. In the OB of untreated NPC1-/- mice, BrdU and cas-3 data showed increased proliferation and apoptotic activity, respectively. At the protein level, Iba1 and GFAP in the OB indicated increased microgliosis and astrogliosis, which was prevented by treatment.Conclusion: Due to the unique plasticity especially of peripheral olfactory components the results show a successful treatment in NPC1 condition with respect to normalization of olfaction. Unchanged mRNA levels for olfactory marker protein and distinct olfactory receptors indicate no effects in the OE in NPC1-/- mice. Olfactory deficits are thus likely due to central deficits at the level of the OB. Further studies are needed to examine if olfactory performance can also be changed at a later onset and interrupted treatment of the disease. Taken together, our results demonstrate that olfactory testing in patients with NPC1 may be successfully used as a biomarker during the monitoring of the treatment

The role of regulatory T cells in antigen-induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4(+)CD25(+ )T cells

It is now generally accepted that CD4(+)CD25(+ )T(reg )cells play a major role in the prevention of autoimmunity and pathological immune responses. Their involvement in the pathogenesis of chronic arthritis is controversial, however, and so we examined their role in experimental antigen-induced arthritis in mice. Depletion of CD25-expressing cells in immunized animals before arthritis induction led to increased cellular and humoral immune responses to the inducing antigen (methylated bovine serum albumin; mBSA) and autoantigens, and to an exacerbation of arthritis, as indicated by clinical (knee joint swelling) and histological scores. Transfer of CD4(+)CD25(+ )cells into immunized mice at the time of induction of antigen-induced arthritis decreased the severity of disease but was not able to cure established arthritis. No significant changes in mBSA-specific immune responses were detected. In vivo migration studies showed a preferential accumulation of CD4(+)CD25(+ )cells in the inflamed joint as compared with CD4(+)CD25(- )cells. These data imply a significant role for CD4(+)CD25(+ )T(reg )cells in the control of chronic arthritis. However, transferred T(reg )cells appear to be unable to counteract established acute or chronic inflammation. This is of considerable importance for the timing of T(reg )cell transfer in potential therapeutic applications

Mobile 3D sensor for documenting maintenance processes of large complex structures

With the new handheld goSCOUT3D sensor system, the entire surface of complex industrial machinery spanning several meters can be captured three-dimensionally within a matter of minutes. In addition, a comprehensive photo collection is registered and precisely assigned to the corresponding 3D object points in one hybrid 2D/3D model. At the basis of the robust 3D digitization are the measuring principles of photogrammetric reconstruction using a high-resolution color camera and simultaneous localization and imaging using a tracking unit. Following image acquisition, the process leading to generation of the complete hybrid model is fully automated. Under continuous movement of the sensor head, up to six images per second and a total of up to several thousand images can be recorded. Those images are then aligned in 3D space and used to reconstruct the 3D model. Results regarding accuracy measurements are presented as well as application examples of digitized technical machinery under maintenance and inspection