260 research outputs found
SB61-21/22-Resolution Advocating for Improved Resident Assistant Working Conditions
SB61-21/22-Resolution Advocating for Improved Resident Assistant Working Conditions. This resolution was approved unanimously during the January 26, 2022 meeting of the Associated Students of the University of Montana (ASUM)
SB38-21/22: Resolution Amending Section 2, Subsection 4 of the ASUM House Rules
SB38-21/22: Resolution Amending Section 2, Subsection 4 of the ASUM House Rules. This resolution passed unanimously during the October 27, 2021 meeting of the Associated Students of the University of Montana (ASUM)
SB34-21/22: Resolution Amending Section 2, Subsection 2 of the ASUM House Rules
SB34-21/22: Resolution Amending Section 2, Subsection 2 of the ASUM House Rules. This resolution passed unanimously during the October 20, 2021 meeting of the Associated Students of the University of Montana (ASUM)
SB16-21/22: Resolution Encouraging The University of Montana to Build and Maintain Emergency Stations on Campus
SB16-21/22: Resolution Encouraging The University of Montana to Build and Maintain Emergency Stations on Campus. This resolution passed unanimously during the September 29, 2021 meeting of the Associated Students of the University of Montana (ASUM)
Introduction: Family Law in the 1990s -- New Problems, Strong Solutions
The 1992 Presidential campaign was fraught with references to family values. While Vice President Quayle took on a fictional television character for choosing to have a child out of wedlock, candidate Clinton was vowing support for the Family Leave Bill and other pro- family measures. Although the political rhetoric of the 1992 campaign was partisan in nature, the emphasis placed on the family by the political parties reflects the seriousness of the problems facing the American family in the 1990s. The American family is not the same entity that it was twenty years ago. Now, nontraditional families, such as single heads of household, divorced families and foster families, outnumber traditional families three to one. The social and economic changes within and around the American family create internal and external conflicts calling for new solutions to resolve emerging problems. The question facing the legal community in dealing with these conflicts will be the extent to which the law can ensure the health, safety, and welfare of the family.
The family has been characterized as a sanctuary, a haven, or a quiet respite; however, the family also can be a place of violence, neglect, abuse, and misery. Children born into violent households often are physically, emotionally, or sexually abused, and frequently extend that violence outward to the world around them. Further, foster children are often lost in the cracks of an overburdened and understaffed system, left to flounder for what support they can garner through their own efforts or to succumb to the cycle of abuse and neglect. The question of whether the law can provide these children with a means to escape abusive situations plagues foster care reform efforts.\u2
The Disfranchisement of Fertile Women in Clinical Trials: The Legal Ramifications of and Solutions for Rectifying the Knowledge Gap
Twice as many women as men receive treatment for clinical depression, yet men benefit more than women from antidepressant drug treatment. Likewise, women use more prescription drugs than men, but suffer proportionally more side effects.\u27 Such disparities stem from the traditional attitude of pharmaceutical companies and researchers to- ward the use of women in clinical trials. In general, researchers have tested drugs on young white males without regard for gender differences, often assuming that data extrapolated from studies on males are readily applicable to females. Even medical treatments designed exclusively for women are developed and tested based on a male model, regardless of the fact that women often react differently to many treatments than men do. Researchers generalize information received from male-oriented studies without sufficient information to show that such treatments will be effective or safe for use by women. The net result has been the marketing of drugs that are less effective for, and often dangerous to, women.
Researchers and pharmaceutical companies historically have given many reasons for their decision to use a male model in drug development and testing. Increasingly, however, the medical community, women\u27s health organizations, Congress, and some administrative agencies believe that the exclusion of women from clinical trials is a grave oversight with potentially devastating consequences.\u27 Recently, government agencies and private organizations have taken steps toward encouraging pharmaceutical companies and researchers to include women in clinical trials, but these efforts have had only moderate success
Liposomal delivery of PDE5 inhibitors and UT-15C to human erythrocytes
Previous studies have shown that the controlled release of adenosine triphosphate (ATP) from human erythrocytes is an important mechanism for the regulation of vascular caliber. However, erythrocytes from patients with pulmonary arterial hypertension (PAH) fail to release ATP in response to the physiological stimuli of exposure to low oxygen tension or mechanical deformation of a magnitude these cells would encounter in the pulmonary circulation. This defect could be a significant contributor to the increased pulmonary vascular resistance (PVR) that is the cause of the pathological increase in vascular pressures in humans with PAH.
One important approach to the treatment of PAH is to reduce PVR with the administration of drugs such as prostacyclin or its analogs and phosphodiesterase 5 (PDE5) inhibitors. These medications can be used alone or in combination and may have serious unwanted side effects that are additive when used in combination.
Here an alternative drug delivery technique using drug-loaded liposomes is investigated that may allow for increased drug efficacy and, possibly, reduced unwanted side effects. Liposomes can encapsulate drugs and deliver them directly to specific cells. This research describes the successful incorporation and delivery of a clinically-used PDE5 inhibitor, tadalafil, via liposomes, to human erythrocytes to increase ATP release from erythrocytes exposed to the prostacyclin analog, UT-15C. This demonstrates the effectiveness of this technique and forms the basis for future in vivo trials to improve drug delivery and patient quality of life. Liposomal delivery, currently underutilized clinically, could represent a new treatment paradigm for patients with circulation issues --Abstract, page iii
SB72-20/21: Resolution Urging the University of Montana to Provide Free Menstrual Hygiene Products in All Campus Restrooms
SB72-20/21: Resolution Urging the University of Montana to Provide Free Menstrual Hygiene Products in All Campus Restrooms. This resolution was approved unanimously during the March 24, 2021 meeting of the Associated Students of the University of Montana (ASUM)
SB24-21/22: Resolution Endorsing The University of Montana Main Campus External Lighting Update Project
SB24-21/22: Resolution Endorsing The University of Montana Main Campus External Lighting Update Project. This resolution passed unanimously during the October 13, 2021 meeting of the Associated Students of the University of Montana (ASUM)
SB03-22/23: Resolution Encouraging the Elimination of Online Fees
SB03-22/23: Resolution Encouraging the Elimination of Online Fees
This resolution passed unanimously at the October 5, 2022 meeting of the Associated Students of the University of Montana
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