Occupational health and safety in the industry 4.0 era: A cause for major concern?

Real-time communication, Big Data, human–machine cooperation, remote sensing, monitoring and process control, autonomous equipment and interconnectivity are becoming major assets in modern industry. As the fourth industrial revolution or Industry 4.0 becomes the predominant reality, it will bring new paradigm shifts, which will have an impact on the management of occupational health and safety (OHS). In the midst of this new and accelerating industrial trend, are we giving due consideration to changes in OHS imperatives? Are the OHS consequences of Industry 4.0 being evaluated properly? Do we stand to lose any of the gains made through proactive approaches? Are there rational grounds for major concerns? In this article, we examine these questions in order to raise consciousness with regard to the integration of OHS into Industry4.0. It is clear that if the technologies driving Industry 4.0 develop in silos and manufacturers’ initiatives are isolated and fragmented, the dangers will multiply and the net impact on OHS will be negative. As major changes are implemented, previous gains in preventive management of workplace health and safety will be at risk. If we are to avoid putting technological progress and OHS on a collision course, researchers, field experts and industrialists will have to collaborate on a smooth transition towards Industry 4.0

Sustainable development in the mining industry: Towards the development of tools for evaluating socioeconomic impact in the Canadian context

In spite of its economic outputs, the Canadian mining sector has suffered from several setbacks that have compromised its reputation. This has led many of its stakeholders to adopt a shift towards a new paradigm focused on sustainable development. In this review of the literature, we identify the impact that mining activities have had on various social, economic and environmental issues in Canadian society. We also survey the criteria and indicators included in various models that may be used to evaluate the adequacy of the transition of mines towards sustainable development. Finally, the strengths and weaknesses of eight tools that have been applied to the socioeconomic impact of mines are analysed. A clear vision of prospects for promoting sustainable development in Canadian mining emerges from this survey. Our analysis reveals important factors not given adequate consideration in the models used currently to evaluate and suggests opportunities to improve these evaluation tools through identification of more relevant criteria and indicators. The research undertaken should incite stakeholders to develop social and economic impact evaluation tools that are better adapted to the Canadian context

Prevention of occupational diseases in small and medium-sized manufacturing enterprises in QUEBEC (CANADA) – Study of prevention management practices

Prevention of accidents and occupational diseases plays a major role in the viability of small and medium-sized manufacturing enterprises. However, occupational health and safety conditions in this setting are often precarious compared to large corporations, in which occupational diseases occur eight times less frequently. In a previous study [1], it has been identified, by reviewing the literature, the measures practiced by managers of businesses in this category in the province of Quebec in their efforts to decrease the incidence of occupational diseases. The initial research work reduced these measures to a catalog of elements of management. In the present article, the findings on the application of these elements will be presented, based on a survey of about 400 manufacturing businesses, of which 252 agreed to answer the questionnaire. The present article provides a descriptive statistic from the analysis of the responses. This work allowed to portray the strengths and deficiencies of occupational disease risk management practices in Quebec based on complete and valid responses from 32 small and medium-sized enterprises (SMEs). Overall, this portrayal reflects a serious effort to take up the cause of occupational health and safety in this type of business. It nevertheless reveals room for improvement of the implementation of health and safety risk management systems, and prevention of musculoskeletal diseases and hearing loss, which were found to occur in respectively 63% and 25% of these companies. This work therefore recommends that these diseases be treated as a priority by researchers and expert practitioners of occupational health and safety

Multi-criteria evaluation of the socioeconomic impact of mining in Canada from a sustainable development perspective: A theoretical model

The socioeconomic impact of mining in Canada has positive and negative aspects. Effective evaluation of its impact suffers from the inadequacy of the criteria and indicators chosen to measure its sustainability and the limitations of the current means used to minimize the subjectivity of expert judgments. Constraints associated with legislation and standards governing mining activities must also be considered. In this study, a theoretical model is proposed for evaluating the socioeconomic impact of mining in Canada. This model combines the multi-criteria analysis methods known as the analytic hierarchy process and fuzzy integrated judgment. Based on a simulation, the model is able to take into account the subjectivity of expert judgments. In addition to reducing this subjectivity and allowing measurement of sensitivity, the model provided an overview of the progress achieved by a mine during its transition towards sustainable development

Oxidative Stress and Mitochondrial Functions in the Intestinal Caco-2/15 Cell Line

Although mitochondrial dysfunction and oxidative stress are central mechanisms in various pathological conditions, they have not been extensively studied in the gastrointestinal tract, which is known to be constantly exposed to luminal oxidants from ingested foods. Key among these is the simultaneous consumption of iron salts and ascorbic acid, which can cause oxidative damage to biomolecules.The objective of the present work was to evaluate how iron-ascorbate (FE/ASC)-mediated lipid peroxidation affects mitochondrion functioning in Caco-2/15 cells. Our results show that treatment of Caco-2/15 cells with FE/ASC (0.2 mM/2 mM) (1) increased malondialdehyde levels assessed by HPLC; (2) reduced ATP production noted by luminescence assay; (3) provoked dysregulation of mitochondrial calcium homeostasis as evidenced by confocal fluorescence microscopy; (4) upregulated the protein expression of cytochrome C and apoptotic inducing factor, indicating exaggerated apoptosis; (5) affected mitochondrial respiratory chain complexes I, II, III and IV; (6) elicited mtDNA lesions as illustrated by the raised levels of 8-OHdG; (7) lowered DNA glycosylase, one of the first lines of defense against 8-OHdG mutagenicity; and (8) altered the gene expression and protein mass of mitochondrial transcription factors (mtTFA, mtTFB1, mtTFB2) without any effects on RNA Polymerase. The presence of the powerful antioxidant BHT (50 microM) prevented the occurrence of oxidative stress and most of the mitochondrial abnormalities.Collectively, our findings indicate that acute exposure of Caco-2/15 cells to FE/ASC-catalyzed peroxidation produces harmful effects on mitochondrial functions and DNA integrity, which are abrogated by the powerful exogenous BHT antioxidant. Functional derangements of mitochondria may have implications in oxidative stress-related disorders such as inflammatory bowel diseases