Line emission from gamma-ray burst environments

The time and angle dependent line and continuum emission from a dense torus around a cosmological gamma-ray burst source is simulated, taking into account photoionization, collisional ionization, recombination, and electron heating and cooling due to various processes. The importance of the hydrodynamical interaction between the torus and the expanding blast wave is stressed. Due to the rapid deceleration of the blast wave as it interacts with the dense torus, the material in the torus will be illuminated by a drastically different photon spectrum than observable through a low-column-density line of sight, and will be heated by the hydrodynamical interaction between the blast wave and the torus. A model calculation to reproduce the Fe K-alpha line emission observed in the X-ray afterglow of GRB 970508 is presented. The results indicate that ~ 10^{-4} solar masses of iron must be concentrated in a region of less than 10^{-3} pc. The illumination of the torus material due to the hydrodynamic interaction of the blast wave with the torus is the dominant heating and ionization mechanism leading to the formation of the iron line. These results suggest that misaligned GRBs may be detectable as X-ray flashes with pronounced iron emission line features.Comment: Accepted for publication in ApJ. Updated recombination rate data; discussion on element abundances added; references update

Monte-Carlo simulations of thermal/nonthermal radiation from a neutron-star magnetospheric accretion shell

We discuss the space-and-time-dependent Monte Carlo code we have developed to simulate the relativistic radiation output from compact astrophysical objects, coupled to a Fokker-Planck code to determine the self-consistent lepton populations. We have applied this code to model the emission from a magnetized neutron star accretion shell near the Alfven radius, reprocessing the radiation from the neutron sar surface. We explore the parameter space defined by the accretion rate, stellar surface field and the level of wave turbulence in the shell. Our results are relevant to the emission from atoll sources, soft-X-ray transient X-ray binaries containing weakly magnetized neutron stars, and to recently suggested models of accretion-powered emission from anomalous X-ray pulsars.Comment: 24 pages, including 7 figures; uses epsf.sty. final version, accepted for publication in ApJ. Extended introduction and discussio

Effects of geometric anisotropy on local field distribution: Ewald-Kornfeld formulation

We have applied the Ewald-Kornfeld formulation to a tetragonal lattice of point dipoles, in an attempt to examine the effects of geometric anisotropy on the local field distribution. The various problems encountered in the computation of the conditionally convergent summation of the near field are addressed and the methods of overcoming them are discussed. The results show that the geometric anisotropy has a significant impact on the local field distribution. The change in the local field can lead to a generalized Clausius-Mossotti equation for the anisotropic case.Comment: Accepted for publications, Journal of Physics: Condensed Matte

Fireballs Loading and the Blast Wave Model of Gamma Ray Bursts

A simple function for the spectral power $P(\epsilon,t) \equiv \nu L(\nu)$ is proposed to model, with 9 parameters, the spectral and temporal evolution of the observed nonthermal synchrotron power flux from GRBs in the blast wave model. Here $\epsilon = h\nu/$m$_e$c$^2$ is the observed dimensionless photon energy and $t$ is the observing time. Assumptions and an issue of lack of self-consistency are spelled out. The spectra are found to be most sensitive to the baryon loading, expressed in terms of the initial bulk Lorentz factor $\Gamma_0$, and an equipartition term $q$ which is assumed to be constant in time and independent of $\Gamma_0$. Expressions are given for the peak spectral power $P_p(t) = P(\epsilon_p,t)$ at the photon energy $\epsilon = \epsilon_p(t)$ of the spectral power peak. A general rule is that the total fireball particle kinetic energy $E_0 \sim \Pi_0 t_d$, where $t_d \propto \Gamma_0^{-8/3}$ is the deceleration time scale and $\Pi_0 \equiv P(\epsilon_p,t_d) \propto \Gamma_0^{8/3}$ is the maximum measured bolometric power output in radiation, during which it is carried primarily by photons with energy ${\cal E}_0 = \epsilon_p(t_d) \propto q\Gamma_0^4$.Comment: 26 pages, including 4 figures, uses epsf.sty, rotate.sty; submitted to ApJ; revised version with extended introduction, redrawn figures, and correction

H_2 Absorption and Fluorescence for Gamma Ray Bursts in Molecular Clouds

If a gamma ray burst with strong UV emission occurs in a molecular cloud, there will be observable consequences resulting from excitation of the surrounding H2. The UV pulse from the GRB will pump H2 into vibrationally-excited levels which produce strong absorption at wavelengths < 1650 A. As a result, both the prompt flash and later afterglow will exhibit strong absorption shortward of 1650 A, with specific spectroscopic features. Such a cutoff in the emission from GRB 980329 may already have been observed by Fruchter et al.; if so, GRB 980329 was at redshift 3.0 < z < 4.4 . BVRI photometry of GRB 990510 could also be explained by H2 absorption if GRB 990510 is at redshift 1.6 < z < 2.3. The fluorescence accompanying the UV pumping of the H2 will result in UV emission from the GRB which can extend over days or months, depending on parameters of the ambient medium and beaming of the GRB flash. The 7.5-13.6 eV fluorescent luminosity is \sim 10^{41.7} erg/s for standard estimates of the parameters of the GRB and the ambient medium. Spectroscopy can distinguish this fluorescent emission from other possible sources of transient optical emission, such as a supernova.Comment: 13 pages, including 4 figures. submitted to Ap.J.(Letters

Lamination And Microstructuring Technology for a Bio-Cell Multiwell array

Microtechnology becomes a versatile tool for biological and biomedical applications. Microwells have been established long but remained non-intelligent up to now. Merging new fabrication techniques and handling concepts with microelectronics enables to realize intelligent microwells suitable for future improved cancer treatment. The described technology depicts the basis for the fabrication of a elecronically enhanced microwell. Thin aluminium sheets are structured by laser micro machining and laminated successively to obtain registration tolerances of the respective layers of 5..10\^A$\mu$m. The microwells lasermachined into the laminate are with 50..80\^A$\mu$m diameter, allowing to hold individual cells within the well. The individual process steps are described and results on the microstructuring are given.Comment: Submitted on behalf of EDA Publishing Association (http://irevues.inist.fr/EDA-Publishing

Broadband Spectral Analysis of PKS 0528+134: A Report on Six Years of EGRET Observations

The multiwavelength spectra of PKS 0528+134 during six years of observations by EGRET have been analyzed using synchrotron self-Compton (SSC) and external radiation Compton (ERC) models. We find that a two-component model, in which the target photons are produced externally to the gamma-ray emitting region, but also including an SSC component, is required to suitably reproduce the spectral energy distributions of the source. Our analysis indicates that there is a trend in the observed properties of PKS 0528+134, as the source goes from a gamma-ray low state to a flaring state. We observe that during the higher gamma-ray states, the bulk Lorentz factor of the jet increases and the ERC component dominates the high-energy emission. Our model calculations indicate the trend that the energies of the electrons giving rise to the synchrotron peak decreases, and the power-ratio of the gamma-ray and low energy spectral components increases, as the source goes from a low to a high gamma-ray state.Comment: 36 pages, 13 figures, final version accepted for publication in ApJ; includes minor modification

Human phosphodiesterase 4D7 (PDE4D7) expression is increased in TMPRSS2-ERG positive primary prostate cancer and independently adds to a reduced risk of post-surgical disease progression

background: There is an acute need to uncover biomarkers that reflect the molecular pathologies, underpinning prostate cancer progression and poor patient outcome. We have previously demonstrated that in prostate cancer cell lines PDE4D7 is downregulated in advanced cases of the disease. To investigate further the prognostic power of PDE4D7 expression during prostate cancer progression and assess how downregulation of this PDE isoform may affect disease outcome, we have examined PDE4D7 expression in physiologically relevant primary human samples. methods: About 1405 patient samples across 8 publically available qPCR, Affymetrix Exon 1.0 ST arrays and RNA sequencing data sets were screened for PDE4D7 expression. The TMPRSS2-ERG gene rearrangement status of patient samples was determined by transformation of the exon array and RNA seq expression data to robust z-scores followed by the application of a threshold &gt;3 to define a positive TMPRSS2-ERG gene fusion event in a tumour sample. results: We demonstrate that PDE4D7 expression positively correlates with primary tumour development. We also show a positive association with the highly prostate cancer-specific gene rearrangement between TMPRSS2 and the ETS transcription factor family member ERG. In addition, we find that in primary TMPRSS2-ERG-positive tumours PDE4D7 expression is significantly positively correlated with low-grade disease and a reduced likelihood of progression after primary treatment. Conversely, PDE4D7 transcript levels become significantly decreased in castration resistant prostate cancer (CRPC). conclusions: We further characterise and add physiological relevance to PDE4D7 as a novel marker that is associated with the development and progression of prostate tumours. We propose that the assessment of PDE4D7 levels may provide a novel, independent predictor of post-surgical disease progression

The prompt X-ray emission of GRB011211: possible evidence of a transient absorption feature

We report on observation results of the prompt X- and gamma-ray emission from GRB011211. This event was detected with the Gamma-Ray Burst Monitor and one of the Wide Field Cameras aboard the BeppoSAX satellite. The optical counterpart to the GRB was soon identified and its redshift determined (z = 2.140), while with the XMM-Newton satellite, the X-ray afterglow emission was detected. Evidence of soft X-ray emission lines was reported by Reeves et al. (2002), but not confirmed by other authors. In investigating the spectral evolution of the prompt emission we find the possible evidence of a transient absorption feature at 6.9^{+0.6}_{-0.5} keV during the rise of the primary event. The significance of the feature is derived with non parametric tests and numerical simulations, finding a chance probability which ranges from 3x10^{-3} down to 4x10^{-4}. The feature shows a Gaussian profile and an equivalent width of 1.2^{+0.5}_{-0.6} keV. We discuss our results and their possible interpretation.Comment: 23 pages, 3 Tables, 6 Figures. Accepted for publication in Astrophysical Journa

The X-ray afterglow of the Gamma-ray burst of May 8, 1997: spectral variability and possible evidence of an iron line

We report the possible detection (99.3% of statistical significance) of redshifted Fe iron line emission in the X-ray afterglow of Gamma-ray burst GRB970508 observed by BeppoSAX. Its energy is consistent with the redshift of the putative host galaxy determined from optical spectroscopy. The line disappeared about 1 day after the burst. We have also analyzed the spectral variability during the outburst event that characterizes the X-ray afterglow of this GRB. The spectrum gets harder during the flare, turning to steep when the flux decreases. The variability, intensity and width of the line indicate that the emitting region should have a mass approximately greater than 0.5 solar masses (assuming the iron abundance similar to its solar value), a size of about 3 times 10^15 cm, be distributed anisotropically, and be moving with sub-relativistic speed. In contrast to the fairly clean environment expected in the merging of two neutron stars, the observed line properties would imply that the site of the burst is embedded in a large mass of material, consistent with pre-explosion ejecta of a very massive star. This material could be related with the outburst observed in the afterglow 1 day after the GRB and with the spectral variations measured during this phase.Comment: To appear in The Astrophysical Journal Letters, AASTEX LateX, 2 PostScript figure