Broadband Spectro-temporal Study on Blazar TXS 1700+685

We attempt to present a multiwavelength variability and correlation study as well as detailed multi-waveband spectral characteristics of the May 2021 $\gamma$-ray flare of the blazar source TXS 1700+685. The multi-wavelength observation from \textit{Fermi}-LAT, \textit{Swift}-XRT/UVOT as well as radio archival data are used for our spectro-temporal investigation. We estimate the variability time-scale of the source from the flux doubling time in different flaring regions detected in \textit{Fermi}-LAT observation and the shortest variability time is used to put a constraint on the minimum Doppler factor and on the size of the emission region. We have detected a statistically significant quasi-periodic oscillation feature (QPO) at $\sim$ 17 days. The broad-band emission is satisfactorily represented during its flaring state with a leptonic synchrotron and inverse Compton component. From the broadband spectral modeling, we observe the external Comptonization of the seed photons originating in the broad line region to be dominant compared to the dusty torus. This is further supported by the fact that the emission region is also found to be residing within the BLR. The equipartition value implies the energy density of the magnetic field in the jet comoving frame is weak, and that is also reflected in the magnetic field and low power corresponding to the magnetic field component of the jet. In order to produce the high energy hump, we need the injection of a large population of high energy electrons and/or the presence of strong magnetic field; and we observe the later component to be sub-dominant in our case. The flat rising and steep falling profile in the $\gamma$-ray SED as well as the break or spectral curvature at $\sim$ 1 GeV are in commensuration with the flat-spectrum radio quasar (FSRQ) nature of the source

Quasi-periodic oscillation detected in γ\gamma-rays in blazar PKS 0346-27

We present a variability study of the blazar PKS 0346-27 from December 2018 to January 2022 in its archival $\gamma$-ray observation by Fermi-LAT. We use the Lomb-Scargle periodogram and the weighted wavelet transform methods in order to detect the presence of periodicity/quasi-periodicity and localize this feature in time and frequency space. The significance of the periodicity feature has been estimated using the Monte-Carlo simulation approach. We have also determined the global significance of the periodicity to test the robustness of our claim. To explore the most probable scenario, we modeled the light curve with both a straight jet and a curved jet model. We detect a periodicity feature of $\sim$ 100 days duration for the entire period of observation with a statistical significance of $3\sigma$, which amounts to a 99.7\% confidence level. The global significance of this feature is found to be 96.96\%. Based on the Akaike Information Criteria, the most probable explanation is that the observed emission is enhanced due to the helical motion of a blob within a curved jet. The origin of this QPO is very likely a region of enhanced emission moving helically inside a curved jet. This work presents strong evidence for jet curvature in the source and an independent (albeit a little serendipitous) procedure to estimate the curvature in blazar jets.Comment: 7 pages, 4 figures, Accepted for publication in A&A, in Pres

Multi-wavelength study of TeV blazar 1ES 1218+304 using gamma-ray, X-ray and optical observations

We report the multi-wavelength study for a high-synchrotron-peaked BL Lac 1ES 1218+304 using near-simultaneous data obtained during the period from January 1, 2018, to May 31, 2021 (MJD 58119-59365) from various instruments including Fermi-LAT, Swift-XRT, AstroSat, and optical from Swift-UVOT $\&$ TUBITAK observatory in Turkey. The source was reported to be flaring in TeV $\gamma$-ray band during 2019, but no significant variation is observed with Fermi-LAT. A sub-hour variability is seen in the SXT light curve, suggesting a compact emission region for their variability. However, hour scale variability is observed in the $\gamma$-ray light curve. A "softer-when-brighter" trend is observed in $\gamma$-rays, and an opposite trend is seen in X-rays suggesting both emissions are produced via two different processes as expected from an HBL source. We have chosen the two epochs in January 2019 to study and compare their physical parameters. A joint fit of SXT and LAXPC provides a constraint on the synchrotron peak, roughly estimated to be $\sim$1.6 keV. A clear shift in the synchrotron peak is observed from $\sim$1 keV to above 10 keV revealing its extreme nature or behaving like an EHBL-type source. The optical observation provides color-index variation as "blue-when-brighter". The broadband SED is fitted with a single-zone SSC model, and their parameters are discussed in the context of a TeV blazar and the possible mechanism behind the broadband emission.Comment: 13 pages, 10 figures, 5 tables, Accepted for publication in MNRA

Simultaneous multi-wavelength observations of the TeV Blazar Mrk 421 during February - March 2003: X-ray and NIR correlated variability

In the present paper, we have reported the result of simultaneous multi-wavelength observations of the TeV blazar Mrk 421 during February $-$ March 2003. In this period, we have observed Mrk 421 using Pachmarhi Array of \v{C}erenkov Telescopes (PACT) of Tata Institute of Fundamental Research at Pachmarhi, India. Other simultaneous data were taken from the published literature and public data archives. We have analyzed the high quality X-ray (2-20 keV) observations from the NASA Rossi X-Ray Timing Explorer (RXTE). We have seen a possible correlated variability between X-ray and J band (1.25 $\mu$) near infrared (NIR) wavelength. This is the first case of X-ray and NIR correlated variability in Mrk 421 or any high energy peaked (HBL) blazar. The correlated variability reported here is indicating a similar origin for NIR and X-ray emission. The emission is not affected much by the environment of the surrounding medium around the central engine of the Mrk 421. The observations are consistent with the shock-in-jet model for the emission of radiations.Comment: 11 pages, 5 figures, Accepted for Publication in ChJA

Cell-surface sensors for real-time probing of cellular environments

Author Manuscript 2012 August 1.The ability to explore cell signalling and cell-to-cell communication is essential for understanding cell biology and developing effective therapeutics. However, it is not yet possible to monitor the interaction of cells with their environments in real time. Here, we show that a fluorescent sensor attached to a cell membrane can detect signalling molecules in the cellular environment. The sensor is an aptamer (a short length of single-stranded DNA) that binds to platelet-derived growth factor (PDGF) and contains a pair of fluorescent dyes. When bound to PDGF, the aptamer changes conformation and the dyes come closer to each other, producing a signal. The sensor, which is covalently attached to the membranes of mesenchymal stem cells, can quantitatively detect with high spatial and temporal resolution PDGF that is added in cell culture medium or secreted by neighbouring cells. The engineered stem cells retain their ability to find their way to the bone marrow and can be monitored in vivo at the single-cell level using intravital microscopy.National Institutes of Health (U.S.) (Grant HL097172)National Institutes of Health (U.S.) (Grant HL095722)National Institutes of Health (U.S.) (Grant DE019191)National Institutes of Health (U.S.) (Grant NIAID 5RC1AI086152)Charles A. Dana FoundationAmerican Heart Association (Grant 0970178N)National Science Foundation (U.S.) (Graduate Fellowship

Multi-frequency Variability Study of Flat-Spectrum Radio Quasar PKS 0346-27

We have presented a multiwavelength temporal and spectral study of the Blazar PKS 0346-27 between the time period 2019 January-2021 December (MJD 58484-59575). We analysed the data collected by Fermi-LAT (gamma-rays), Swift-XRT (x-rays) and Swift-UVOT (ultra-violet). Flaring episodes are identified by analysing the gamma-ray lightcurve. Flares are fitted using polynomial fit. We have found rapid variability on time scales of hours during brightest flaring activity, which implies that the emission region is very compact. The broadband emission mechanism was studied by modelling the simultaneous multi waveband Spectral Energy Distributions (SED) using leptonic emission mechanism. We found that the optical-UV and X-ray data can be explained by the synchrotron emission. However, the high energy peak is best fitted with external Compton of disk photon rather than the BLR or DT. Our modeling also suggest that the flare 1 and flare 5 have more jet power than flare 2 and 3 which can be caused by different processes. It also suggest that all the flares are produced in different situation. An auto correlation of gamma-ray lightcure was done and concluded the possibility of the source being gravitationally lensed. We have also produced the power spectral density for this source and a powerlaw seems to produce the best fit with slope 2.15+/-0.87 suggesting variability in this source is dominated by stochastic process. This source could be a promising target for upcoming CTA for its harder spectrum at lower energies (tens of GeV)

Evaluation of Urban Sustainability through Perceived Importance, Performance, Satisfaction and Loyalty: An Integrated IPA–SEM-Based Modelling Approach

In recent years, there has been a surge in research pertaining to sustainable urban development. Importance–performance analysis (IPA) has emerged as one of the most widely used methods. However, few studies have combined IPA with structural equation modelling (SEM). This study introduces and evaluates an integrated IPA–SEM approach to assess the impact of perceived importance and performance of sustainable city dimensions on residents’ satisfaction and loyalty. The data for this study were collected from 425 survey respondents residing in Siliguri City of West Bengal, India. The results indicate that the ‘Keep Up the Good Work’ quadrant, consisting of social quality, connectivity conditions, and environmental quality, significantly and positively affected satisfaction. On the other hand, the ‘Concentrate Here’ quadrant concerning environmental pollution presented a negative yet insignificant relationship with satisfaction while both the ‘Low Priority’ and ‘Potential Overkill’ quadrants demonstrated no notable influence. Furthermore, a robust positive correlation between satisfaction and loyalty is confirmed. Overall, the findings offer valuable implications for urban planning, policy-making, and strategies aimed at enhancing Siliguri residents’ quality of life