Genome-wide association study for 13 udder traits from linear type classification in cattle

Udder conformation traits are known to correlate with the incidence of clinical mastitis and the length of productive life. The results of a genome-wide association study based on imputed high-density genotypes of 1,637 -Brown Swiss sires and de-regressed breeding values for 13 udder traits are presented here. For seven traits significant signals could be observed in five regions on BTA3, BTA5, BTA6, BTA17, and BTA25. For fore udder length and teats diameter significant SNPs were found in a known region around 90 Mb on BTA6. For the trait rear udder height significant SNPs are positioned in the coding region of the SNX29gene. Several significant SNPs around 62 Mb on BTA17 are associated with the traits rear udder width, frontteat placement and rear teat placement. The function of potential candidate genes and the influence of substructure will be addressed as next steps

Fieber - Thema seit Jahrtausenden

Since the antiquity up to the 19th century fever goes for an illness of its own rights. About 1900 temperature measurement has become clinical routine and fever synonymous with elevated body heat. In the time before accelerated pulse rate was the pathognomic sign. The detection of specific pathogen organisms leads to a new understanding of nosology and to the dissolution of the fever entity. However the antipyretic therapy remains essentially the same until the appearance of antibiotics