178 research outputs found
Influence of hydrogen on paramagnetic defects induced by UV laser exposure in natural silica
Diffusion limited reactions of point defects were investigated in amorphous
SiO2 exposed to UV laser light. Electron spin resonance and in situ absorption
measurements at room temperature evidenced the annealing of E' centers and the
growth of H(II) centers both occurring in the post-irradiation stage and
lasting a few hours. These transients are caused by reactions involving
molecular hydrogen H2, made available by dimerization of radiolytic H0.Comment: Submitted to Physica Status Solid
Modeling and simulation of a digital control design approach for power supply systems
Electronic designers need to model and simulate system features as close as possible to its effective behaviour. Moreover, today, electronics systems are often composed of mixed analog and digital components. The increasing complexity has led to the use of different simulation softwares, each one specific for a particular level of abstraction: mathematical, circuital, behavioural, etc. In order to simulate the entire system these softwares should work together: co-simulation is necessary for digitally controlled power electronics systems. In this paper, the modeling of a digitally controlled switching power supply system using MATLAB/Simulink, ALDEC Active-HDL and Powersys PSIM is presented. The power converter is modelled in PSIM, the digital control is described in VHDL by using Active-HDL, and the complete system is simulated in MATLAB/Simulink environment. This design approach presents all the advantages of each used software and all its features will be discussed. The comparison between simulation and experimental results of the digitally controlled step-down converter prototype are reported
H(II) centers in natural silica under repeated UV laser irradiations
We investigated the kinetics of H(II) centers (=Ge'-H) in natural silica
under repeated 266nm UV irradiations performed by a Nd:YAG pulsed laser. UV
photons temporarily destroy these paramagnetic defects, their reduction being
complete within 250 pulses. After re-irradiation, H(II) centers grow again, and
the observed recovery kinetics depends on the irradiation dose; multiple 2000
pulses re-irradiations induce the same post-irradiation kinetics of H(II)
centers after each exposure cycle. The analysis of these effects allows us to
achieve a deeper understanding of the dynamics of the centers during and after
laser irradiation.Comment: Submitted to Journal of Non Crystalline Solid
Optical properties of Ge-oxygen defect center embedded in silica films
The photo-luminescence features of Ge-oxygen defect centers in a 100nm thick
Ge-doped silica film on a pure silica substrate were investigated by looking at
the emission spectra and time decay detected under synchrotron radiation
excitation in the 10-300 K temperature range. This center exhibits two
luminescence bands centered at 4.3eV and 3.2eV associated with its
de-excitation from singlet (S1) and triplet (T1) states, respectively, that are
linked by an intersystem crossing process. The comparison with results obtained
from a bulk Ge-doped silica sample evidences that the efficiency of the
intersystem crossing rate depends on the properties of the matrix embedding the
Ge-oxygen defect centers, being more effective in the film than in the bulk
counterpart.Comment: 10 pages, 3 figures, in press on J. Non cryst. solids (2007
Portuguese cacholeira blood sausage: A first taste of its microbiota and volatile organic compounds
Among typical Portuguese sausages, the cacholeira blood sausage undoubtedly represents one of the most popular preparations. To the authors’ knowledge, a lack of information on both the microbiota and the volatile organic compounds (VOCs) of this blood-containing sausage emerges from the available scientific literature. This study represents the first characterization of physico-chemical, microbiological and volatile traits of Portuguese cacholeira blood sausage. To this end, ready-to-eat cacholeira blood sausages were collected from two production batches manufactured in summer (batch 1) and autumn (batch 2). Viable counts showed active microbial communities mainly composed by lactic acid bacteria, coagulase negative cocci, enterococci and eumycetes. The metataxonomic approach showed a simple bacterial composition, which was dominated by Lactobacillus sakei in both the analyzed batches (1 and 2) considered. Carnobacterium, Enterococcus, Kluyvera, Lactococcus and Serratia were found as minor genera. The mycobiota varied according to the production season. Batch 1 was dominated by Starmerella apicola, Debaryomyces hansenii and Candida tropicalis, whereas batch 2 was dominated by D. hansenii. Moreover, Aspergillus spp., Kurtzmaniella zeylanoides, Saccharomyces cerevisiae, Kurtzmaniella santamariae, Brettanomyces bruxellensis and Pichia kluyveri were detected in both the batches as minority species. Seventy-two volatile compounds were identified, including esters, phenols, terpenoids, acids, alcohols, ketones, aldehydes, lactones, furans, sulphur and nitrogen compounds. Significant differences were seen in the amount of some compounds, as a feasible consequence of differences in the raw materials, artisan production and seasonality
Radiation hardening techniques for rare-earth based optical fibers and amplifiers
Er/Yb doped fibers and amplifiers have been shown to be very radiation sensitive, limiting their integration in space. We present an approach including successive hardening techniques to enhance their radiation tolerance. The efficiency of our
approach is demonstrated by comparing the radiation responses of optical amplifiers made with same lengths of different rare-earth doped fibers and exposed to gamma-rays. Previous studies indicated that such amplifiers suffered significant degradation for doses exceeding 10 krad. Applying our techniques significantly enhances the amplifier radiation resistance, resulting in a very limited degradation up to 50 krad. Our optimization techniques concern the fiber composition, some possible pre-treatments and the interest of simulation tools used to harden by design the amplifiers.
We showed that adding cerium inside the fiber phosphosilicate-based core strongly decreases the fiber radiation
sensitivity compared to the standard fiber. For both fibers, a pre-treatment with hydrogen permits to enhance again the fiber resistance. Furthermore, simulations tools can also be used to improve the tolerance of the fiber amplifier by
helping identifying the best amplifier configuration for operation in the radiative environment
Structural relaxation of E' gamma centers in amorphous silica
We report experimental evidence of the existence of two variants of the E'
gamma centers induced in silica by gamma rays at room temperature. The two
variants are distinguishable by the fine features of their line shapes in
paramagnetic resonance spectra. These features suggest that the two E' gamma
differ for their topology. We find a thermally induced interconversion between
the centers with an activation energy of about 34 meV. Hints are also found for
the existence of a structural configuration of minimum energy and of a
metastable state.Comment: 4 pages, 2 figures, submitted to Phys. Rev. Let
Duchenne's muscular dystrophy involves a defective transsulfuration pathway activity
Duchenne muscular dystrophy (DMD) is the most frequent X chromosome-linked disease caused by mutations in the gene encoding for dystrophin, leading to progressive and unstoppable degeneration of skeletal muscle tissues. Despite recent advances in the understanding of the molecular processes involved in the pathogenesis of DMD, there is still no cure. In this study, we aim at investigating the potential involvement of the transsulfuration pathway (TSP), and its by-end product namely hydrogen sulfide (H2S), in primary human myoblasts isolated from DMD donors and skeletal muscles of dystrophic (mdx) mice. In myoblasts of DMD donors, we demonstrate that the expression of key genes regulating the H2S production and TSP activity, including cystathionine γ lyase (CSE), cystathionine beta-synthase (CBS), 3 mercaptopyruvate sulfurtransferase (3-MST), cysteine dioxygenase (CDO), cysteine sulfonic acid decarboxylase (CSAD), glutathione synthase (GS) and γ -glutamylcysteine synthetase (γ-GCS) is reduced. Starting from these findings, using Nuclear Magnetic Resonance (NMR) and quantitative Polymerase Chain Reaction (qPCR) we show that the levels of TSP-related metabolites such as methionine, glycine, glutathione, glutamate and taurine, as well as the expression levels of the aforementioned TSP related genes, are significantly reduced in skeletal muscles of mdx mice compared to healthy controls, at both an early (7 weeks) and overt (17 weeks) stage of the disease. Importantly, the treatment with sodium hydrosulfide (NaHS), a commonly used H2S donor, fully recovers the impaired locomotor activity in both 7 and 17 old mdx mice. This is an effect attributable to the reduced expression of pro-inflammatory markers and restoration of autophagy in skeletal muscle tissues. In conclusion, our study uncovers a defective TSP pathway activity in DMD and highlights the role of H2S-donors for novel and safe adjuvant therapy to treat symptoms of DMD
- …