Inherited thrombophilia in young Indian adults presenting with thrombotic vascular events

Background: There is limited Indian data available regarding inherited thrombophilias. This study was to determine the prevalence of inherited thrombophilias in young Indian patients presenting with thrombotic events.Methods: This study was done at a tertiary hospital in Western India over a period of 20 months. Epidemiological, clinical and laboratory data was recorded of all consecutive patients aged 16 to 45 admitted with arterial and venous thrombotic vascular events. Blood samples for the thrombophilia profile were sent. Data was tabulated and analyzed using microsoft excel and graph pad software.Results: 49 patients aged 15 to 45 years, admitted with thrombotic vascular events a period of 20 months were included. 26 (53.1%) were male. The mean age was 22.2±7 years. 20 (40.8%) patients; 10 (38.5%) males and 10 (43.5%) females had at least one thrombophilia. The commonest thrombophilia in both arterial and venous thrombotic events was hyperhomocysteinemia.Conclusions: Young patients with thrombotic vascular events should be tested for thrombophilias since they are an important risk factor in this subset of patients

A case of mobile right ventricular thrombus with massive pulmonary thromboembolism

In patients with pulmonary thromboembolism, right heart thrombi are uncommon or underdiagnosed. They may form in situ or arise due to migration from the peripheral venous system. Their presence in pulmonary embolism indicates a grave prognosis and complicates treatment decisions. We report a case of mobile right ventricular thrombus with massive pulmonary thromboembolism who had a rapid fatal course despite early treatment

Successful percutaneous retrieval of unusually knotted temporary pacemaker lead

Implantation of temporary pacemaker lead is commonly performed procedure and is usually safe, but can sometimes develop rare and serious complication like intracardiac lead knotting which may require challenging retrieval techniques. We report a case of successful percutaneous retrieval of unusually knotted right internal jugular venous temporary pacing lead via left femoral transvenous approach using snare over a long sheath after cutting the electrode proximally and thus avoiding any surgical intervention. Keywords: Electrode, Knotted, Pacemaker, Snare, Temporary pacemaker lea