1,354 research outputs found
Recent insights in the potential role of imaging modalities for diagnosing patients with primary Sjogren's syndrome
Recent insights in the potential role of imaging modalities for diagnosing patients with primary Sjogren's syndrome
EULAR Sjogren's syndrome study group:an eSSential way to address the unmet needs of the disease
EULAR Sjogren's syndrome study group:an eSSential way to address the unmet needs of the disease
EULAR Sjogren's syndrome study group:an eSSential way to address the unmet needs of the disease
EULAR Sjogren's syndrome study group:an eSSential way to address the unmet needs of the disease
Undernutrition and sarcopenic obesity:underrecognised conditions in patients with Sjögren's syndrome?
Undernutrition and sarcopenic obesity:underrecognised conditions in patients with Sjögren's syndrome?
Advances, limitations and future perspectives in the diagnosis and management of dry eye in Sjogren's syndrome
Primary Sjogren's syndrome is a complex systemic autoimmune disorder that primarily affects exocrine glands such as the lacrimal glands. Dry eye disease is one of the most prevalent complications of Sjogren's syndrome, affecting most patients. It significantly impairs quality of life and management is often difficult and unsatisfactory, in part due to weak correlation between symptoms and signs and poor recognition of the three main subtypes aqueous-deficient, evaporative and neuropathic dry eye. This review provides an overview of key aspects of dry eye disease, such as its multifactorial aetiology and recent insights into pathophysiology. The uses and pitfalls of commonly-used diagnostic tests for dry eye are reviewed, as well as the increasing number of new imaging technologies and biomarkers to refine diagnosis. There are many current and emerging treatment options for dry eye in Sjogren's syndrome, but high-level evidence of efficacy is mostly lacking, as are evidence-based treatment algorithms. All these aspects make the management of dry eye in Sjogren's syndrome challenging
Advances, limitations and future perspectives in the diagnosis and management of dry eye in Sjogren's syndrome
Primary Sjogren's syndrome is a complex systemic autoimmune disorder that primarily affects exocrine glands such as the lacrimal glands. Dry eye disease is one of the most prevalent complications of Sjogren's syndrome, affecting most patients. It significantly impairs quality of life and management is often difficult and unsatisfactory, in part due to weak correlation between symptoms and signs and poor recognition of the three main subtypes aqueous-deficient, evaporative and neuropathic dry eye. This review provides an overview of key aspects of dry eye disease, such as its multifactorial aetiology and recent insights into pathophysiology. The uses and pitfalls of commonly-used diagnostic tests for dry eye are reviewed, as well as the increasing number of new imaging technologies and biomarkers to refine diagnosis. There are many current and emerging treatment options for dry eye in Sjogren's syndrome, but high-level evidence of efficacy is mostly lacking, as are evidence-based treatment algorithms. All these aspects make the management of dry eye in Sjogren's syndrome challenging
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