1,966 research outputs found

    Modelling Green VTOL Concept Designs for Reliability and Efficiency

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    All-electric and hybrid-electric aircraft are a future transport goal and a possible ‘green’ solution to increasing climate-related pressures for aviation. Ensuring the safety of passengers is of high importance, informed through appropriate reliability predictions to satisfy emerging flight certification requirements. This paper introduces another important consideration related to redundancy offered by multiplex electric motors, a maturing technology which could help electric aircraft manufacturers meet the high reliability targets being set. A concept design methodology is overviewed involving a symbolic representation of aircraft and block modelling of two important figures of merit, reliability, and efficiency, supported by data. This leads to a comparative study of green aircraft configurations indicating which have the most potential now, and in the future. Two main case studies are then presented: an electric tail rotor retrofitted to an existing turbine powered helicopter (hybrid) and an eVTOL aircraft (all-electric), demonstrating the impact of multiplex level and number of propulsion channels on meeting target reliabilities. The paper closes with a summary of the important contribution to be made by multiplex electric machines, well as the advancements necessary for green VTOL aircraft sub-systems, e.g., power control unit and batteries, to improve reliability predictions and safety further

    An Unexpected Outcome of a Pediatric Simulation Encounter for Occupational Therapy Students.

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    This presentation reviewed how to plan and implement a pediatric simulated educational experience to align with the targeted course learning objective(s). Participants learned how to incorporate best practices into simulation education in order to advance occupational therapy education

    Role of the loop segment in the urinary concentrating defect of hypercalcemia

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    Role of the loop segment in the urinary concentrating defect of hypercalcemia. Hypercalcemia is associated with impaired urinary concentrating ability. To explore the mechanism(s) by which hypercalcemia impairs chloride transport in the loop of Henle, we carried out in vivo microperfusion of the loop segment in Sprague–Dawley rats rendered acutely hypercalcemie (12.1 ± 0.1 mg/dliter) by calcium gluconate infusion. Control rats were infused with sodium gluconate and had normal plasma calcium (8.0 ± 0.2 mg/dliter). Compared to control, fractional chloride reabsorption was decreased (61 ± 4 to 50 ± 3%; P < 0.05) and early distal chloride increased 74 ± 6 to 98 ± 3 mEq/liter (P < 0.001) in hypercalcemia. During hypercalcemia, infusion of verapamil failed to increase fractional chloride reabsorption (49 ± 4%; P < 0.05) or decrease early distal chloride (95 ± 2; P < 0.05) toward control values. Similarly, indomethacin did not improve fractional chloride reabsorption (48 ± 4%; P < 0.05) or distal chloride concentration (93 ± 7; P < 0.05). In control rats infused with Ringers HCO3, the addition of calcium 8.0 mEq/liter to the perfusate increased early distal calcium (0.22 to 3.11 mEq/liter) but was associated with no change in fractional chloride reabsorption (-6 ± 6%) and a slight decrease in early distal chloride (-9 ± 3 mEq/liter; P < 0.05). These data are consistent with the hypothesis that an elevated plasma, not luminal calcium, concentration impairs chloride reabsorption in the loop segment, primarily the ADH–stimulated component. This may have an important role in the urinary concentrating defect of hypercalcemia

    A Woman Gets Tired Of One Man All The Time

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    A couple walking by a man, who watches themhttps://scholarsjunction.msstate.edu/cht-sheet-music/7500/thumbnail.jp

    The Cootie Crawl

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    Cupid watching man and woman dancehttps://scholarsjunction.msstate.edu/cht-sheet-music/13398/thumbnail.jp

    Characterization of flax germplasm for resistance to fusarium wilt

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    Non-Peer ReviewedFusarium wilt of flax (Linum usitatissimum L.) caused by Fusarium oxysporum f. sp. lini (Fol) is an economically important disease that can result in severe yield losses. Due to the pathogen’s ability to survive in soil for long periods, it is essential to identify fusarium wilt resistant flax varieties. The objectives of the study were to phenotype and compare a recombinant inbred line (RIL) population of flax in a controlled environment and in field wilt nurseries. Disease reaction of a subset (160) of RIL lines developed from cultivars ‘Aurore’ (moderately resistant) and ‘Oliver’ (susceptible) was assessed under controlled environment conditions to two Fol isolates. Disease severity was determined and the area under the disease progress curve (AUDPC) was calculated. The population varied in response from resistant to highly susceptible, indicating that resistant to wilt was probably polygenic. Twenty-eight days after inoculation, 14% and 5% of the RILs were severely wilted (scores of 8 and 9, with isolates 131 and 81, respectively). Plant height was negatively correlated with AUDPC (r2= -0.13155 for 131 and r2=-0.29841 for 81). Similarly, in the field in wilt nurseries, at Saskatoon and Morden, evaluation of the full set of 200 RILs, the disease reaction varied from resistant to susceptible, with 21% and 42% of RILs severely wilted (rated 8 and 9) at each site at the green boll stage. The results from the two locations were significantly different, although moderately correlated (r2=0.6127). The 160 RILs in controlled environment inoculated with isolates 131 and 81 showed a higher correlation for disease severity at 28 days after inoculation, with the wilt nursery in Saskatoon (r= 0.40028 and r2=0.38046) as compared to Morden (r2=0.33016 and r2=0.21140) at green boll stage. Differences in environmental and experimental conditions (such as seeding date) at the two locations, as well as different Fol strains in the soil combined with the subjectivity of the grading system may explain the differences between locations

    Medicinal plants from the Himalayan region as potential novel antimicrobial and anti-inflammatory skin treatments

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    Background and Objectives: Adequate treatment of wounds remains one of the major medical needs globally, most notably in the regions with poor or limited access to health care. In many local and traditional systems of medicine, plants are often widely used for treating infected wounds. / Aim and objectives: The overarching aim of this project was selection of potential species for use in a future treatment by combining with plant resources with aspects of antimicrobial photodynamic therapy (aPDT). Specifically, we focussed on species used locally in the Himalayan region for the treatment of skin disorders and then assessed the existing pharmacological evidence for key species based on the published evidence available. / Methods: Database searches were performed to identify relevant publications describing local and traditional uses of plants in the Himalayan region of Bhutan, PR China, India, Nepal and Pakistan. Using the Global Biodiversity Information Facility (GBIF), species were researched in terms of their distribution including in different climatic regions, focussing on species mostly found in higher climatic zones (based on the Köppen–Geiger climate classification). For species used in three or more countries and restricted to the higher altitudes, data on safety, pharmacology, as it relates to dermatological conditions, and phytochemistry were retrieved. / Key findings: The study identified a total of 606 species that are used in the treatment of various skin conditions often associated with infections reported in 84 articles. Common weeds like Ageratum conyzoides and Bidens pilosa, widely used and cultivated species like Centealla asiatiaca and Prunus armenica were excluded. This ultimately led to the identification of a core group of five widely used species restricted to the Himalayan region (Cedrus deodara, Nardostachys jatamansi, Pinus wallichiana, Pinus roxburghii and Valeriana jatamansi). / Conclusions: Here we apply a novel approach comprising an assessment of the published information on the use of medicinal plants (i.e. local and traditional knowledge) in the context of their potential to be used in a biomedical form of clinical treatment – aPDT. Then, once sustainable sourcing based on access and benefit-sharing arrangements is in place, these species are investigated for their potential in wound treatment. Ultimately, the goal is to develop a new baseline for primary health care in some of the regions of the world with poor or limited access to health care
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