2,213 research outputs found
Unification: An international aerospace information opportunity
Science and technology projects are becoming more and more international and interdisciplinary. Other parts of the world, notably Europe, are increasingly powerful players in the aerospace industry. This change has led to the development of various aerospace information initiatives in other countries. With scarce resources in all areas of government and industry, the NASA STI Program is reviewing its current acquisition and exchange practices and policies to factor in the changing requirements and new opportunities within the international community. Current NASA goals and activities are reviewed with a new view toward developing a scenario for establishing an international aerospace database, maintaining compatibility among national aerospace information systems, eliminating duplication of effort, and sharing resources through international cooperation wherever possible
Data policy and availability supporting global change research, development, and decision-making: An information perspective
An explosion of information has created a crisis for today's information age. It has to be determined how to use the best available information sources, tools, and technology. To do this it is necessary to have leadership at the interagency level to promote a coherent information policy. It is also important to find ways to educate the users of information regarding the tools available to them. Advances in technology resulted in efforts to shift from Disciplinary and Mission-oriented Systems to Decision Support Systems and Personalized Information Systems. One such effort is being made by the Interagency Working Group on Data Management for Global Change (IAWGDMGC). Five federal agencies - the Department of Commerce (DOC), Department of Energy (DOE), National Aeronautics and Space Administration (NASA), National Library of Medicine (NLM), and Department of Defense (DOD) - have an on-going cooperative information management group, CENDI (Commerce, Energy, NASA, NLM, and Defense Information), that is meeting the challenge of coordinating and integrating their information management systems. Although it is beginning to be technically feasible to have a system with text, bibliographic, and numeric data online for the user to manipulate at the user's own workstation, it will require national recognition that the resource investment in such a system is worthwhile, in order to promote its full development. It also requires close cooperation between the producers and users of the information - that is, the research and policy community, and the information community. National resources need to be mobilized in a coordinated manner to move people into the next generation of information support systems
Labor and the Labor Process in a Limited Entry Fishery
We examine aspects of labor in the harvesting sector of the surf clam/ocean quahog industry of the mid-Atlantic region of the United States in the context of limited entry. Vessel owners are both diversifying and cutting back on labor costs through crew consolidation in response to difficulties in the sea clam industry. A survey of crew-members on job satisfaction reveals more about the preferences and experiences of labor. We make predictions about the fate of labor under a new management regime based on individual transferable quotas. The analysis is intended to bring the interests of crew-members into the decision-making process and to improve the basis for predicting how future regulatory measures may affect crewing.fishery management, labor, crewing, Atlantic sea clams, limited entry, social impact, Environmental Economics and Policy, Labor and Human Capital, Resource /Energy Economics and Policy,
The Stanford Health Assessment Questionnaire: Dimensions and Practical Applications
The ability to effectively measure health-related quality-of-life longitudinally is central to describing the impacts of disease, treatment, or other insults, including normal aging, upon the patient. Over the last two decades, assessment of patient health status has undergone a dramatic paradigm shift, evolving from a predominant reliance on biochemical and physical measurements, such as erythrocyte sedimentation rate, lipid profiles, or radiographs, to an emphasis upon health outcomes based on the patient's personal appreciation of their illness. The Health Assessment Questionnaire (HAQ), published in 1980, was among the first instruments based on generic, patient-centered dimensions. The HAQ was designed to represent a model of patient-oriented outcome assessment and has played a major role in many diverse areas such as prediction of successful aging, inversion of the therapeutic pyramid in rheumatoid arthritis (RA), quantification of NSAID gastropathy, development of risk factor models for osteoarthrosis, and examination of mortality risks in RA. Evidenced by its use over the past two decades in diverse settings, the HAQ has established itself as a valuable, effective, and sensitive tool for measurement of health status. It is available in more than 60 languages and is supported by a bibliography of more than 500 references. It has increased the credibility and use of validated self-report measurement techniques as a quantifiable set of hard data endpoints and has contributed to a new appreciation of outcome assessment. In this article, information regarding the HAQ's development, content, dissemination and reference sources for its uses, translations, and validations are provided
Global atmospheric moisture variability
Research efforts during FY-88 have focused on completion of several projects relating to analysis of FGGE data during SOP-1 and on expanded studies of global atmospheric moisture. In particular, a revised paper on the relationship between diabatic heating and baroclinicity in the South Pacific Convergence Zone (SPCZ) was submitted. A summary of completed studies on diagnostic convective parameterization was presented at the Satellite Meteorology and Oceanography Convergence last February. These investigations of diabatic heating in the SPCZ have demonstrated the requirement for a more quantitative description of atmospheric moisture. As a result, efforts were directed toward use of passive remote microwave measurements from the Nimbus-7 SMMR and the DOD's Special Sensor Microwave Imager (SSMI/I) as critical sources of moisture data. Activities this year are summarized
Venus and Leadership: Women Hospitality Leaders
The authors report on a survey of 234 women executives in the hospitality industry using factor analysis to discover the seven underlying dimensions of women leaders: perseverance, trust, inner values, responsibility, stewardship, communication, and vision
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Transcriptomic Profiles of Monocyte-Derived Macrophages in Response to Escherichia coli is Associated with the Host Genetics.
Reactive Nitrogen Species (RNS) are a group of bactericidal molecules produced by macrophages in response to pathogens in a process called oxidative burst. Nitric oxide (NO-) is a member of RNS produced from arginine by inducible Nitric Oxide Synthase (iNOS) enzyme. The activity of iNOS and production of NO- by macrophages following stimulation is one of the indicators of macrophage polarization towards M1/proinflammatory. Production of NO- by bovine monocyte-derived macrophage (MDM) and mouse peritoneal macrophages has been shown to be strongly associated with host genetic with the heritability of 0.776 in bovine MDM and 0.8 in mouse peritoneal macrophages. However, the mechanism of genetic regulation of macrophage response has remained less explored. In the current study, the transcriptome of bovine MDMs was compared between two extreme phenotypes that had been classified as high and low responder based on NO- production. The results showed that 179 and 392 genes were differentially expressed (DE) between high and low responder groups at 3 and 18 hours after exposure to Escherichia coli, respectively. A set of 11 Transcription Factors (TFs) (STAT1, IRF7, SPI1, STAT4, IRF1, HIF1A, FOXO3, REL, NFAT5, HIC1, and IRF4) at 3 hours and a set of 13 TFs (STAT1, IRF1, HIF1A, STAT4, ATF4, TP63, EGR1, CDKN2A, RBL1, E2F1, PRDM1, GATA3, and IRF4) at 18 hours after exposure to E. coli were identified to be differentially regulated between the high and low responder phenotypes. These TFs were found to be divided into two clusters of inflammatory- and hypoxia-related TFs. Functional analysis revealed that some key canonical pathways such as phagocytosis, chemotaxis, antigen presentation, and cell-to-cell signalling are enriched among the over-expressed genes by high responder phenotype. Based on the results of this study, it was inferred that the functional characteristics of bovine MDMs are associated with NO-based classification. Since NO- production is strongly associated with host genetics, this study for the first time shows the distinct proinflammatory profiles of macrophages are controlled by the natural genetic polymorphism in an outbred population. In addition, the results suggest that genetics can be considered as a new dimension in the current model of macrophage polarization which is currently described by the combination of stimulants, only
The Concept of Social Exclusion and Rural Development Policy
Since the early 1970s rural research and public education programs have been intensified in efforts to improve living conditions and strengthen community life in rural America (Southern Perspectives 2000). During much of the 1990s, the nation, including the rural South, experienced a growing economy, a booming stock market, and declining unemployment rates (Gibbs 2001). However, many serious social problems traditionally associated with the rural South remain to this day (Gibbs 2001). This paper introduces the concept of social exclusion, used extensively in European countries and now part of the European Union\u27s official lexicon. Social exclusion is defined as the process and the resulting condition in which specific social entities are fully or partially prevented from acquiring the basic necessities of life. Further components are that it is seen as a product of the social system, not an individual attribute, and that it is multi-dimensional and dynamic in time and space. It is argued that the concept of social exclusion should be incorporated into rural development policy discourse in the United States. This would aid in countering the predominant pattern of neglect in rural development policies and programs in addressing the persistent problems which exist
Changing the Health Care System: Opinions of Rural and Urban Residents
This paper examines the opinions of rural and urban residents toward a full health care system provided by the government. The data used in the study come from a statewide poll conducted by the Louisiana Department of Health and Hospitals. Because of a greater need for health care reform in rural areas, it was assumed that rural Louisianians might be more supportive of a government health care system than their urban counterparts. However, analysis of the data indicates that a person\u27s residence had no statistically significant effect on attitudes toward government sponsored health care
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