Towards Understanding the Gene-Specific Roles of GATA Factors in Heart Development : Does GATA4 Lead the Way?

Funding: This work is supported by the British Heart Foundation (BHF): programme grant number: RG/18/8/33673 to Professor Stefan Hoppler. Acknowledgments: I would like to thank Stefan Hoppler for providing critical comments as well as valuable and constructive suggestions for the manuscript.Peer reviewedPublisher PD

Educando para la ciudadanía global. Una experiencia de investigación cooperativa entre docentes y profesionales de las ONGD

En este artículo se describe el proceso y se presentan los resultados de un proyecto de investigación cooperativa (IC) realizado en Valencia entre febrero 2010 y marzo 2011. Su objetivo fue reflexionar sobre los significados y las prácticas educativas que docentes de primaria, secundaria y universidad pueden realizar en conjunto con las ONGD para potenciar la ciudadanía global en el sistema educativo formal. El artículo comienza con una reflexión sobre la educación para el desarrollo. Posteriormente, se destacan algunos aspectos relevantes de la IC, se describe el proceso seguido y las técnicas empleadas y se discuten algunas reflexiones que se dieron sobre la ciudadanía global y los espacios educativos. Por último se detallan unas conclusiones sobre lo que la metodología de la IC puede aportar a la investigación en educación

Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis

This work was supported by British Heart Foundation (BHF Project Grant no PG/13/23/30080 to B.A.A and S.H.), Biotechnology and Biological Sciences Research Council (BB/M001695/1 to S.H.) and the University of Aberdeen (for A.T.L). Acknowledgements We’re grateful to Ms Yvonne Turnbull and Ms Kate Watt for technical assistance and lab management. We would like to thank Professor Cedric Blanpain and Dr Xionghui Li from Université Libre de Bruxelles for providing training of ES cell manipulation and Mesp1/Gata4 cell lines. We are grateful to Professor Todd Evans from Weill Cornell Medical College for generously providing iGata ES cell lines. We also would like to thank Professor Aaron Zorn and Scott Rankin for providing Xsox18 plasmid.Peer reviewedPublisher PD

Prediction of service life of polymeric sealant compositions for fuel tanks in aerospace structures from measurements of viscoelastic properties Annual report

Prediction of service life of polymeric sealers for fuel tanks from viscoelastic measurement

Public-Private Partnerships and Insurance Regulation

A public-private partnership (PPP) is an institutional arrangement that embodies a collaborative approach to policy and regulation; it is a joint venture between the government and one or more private sector entities. Joint financing partnerships link public financing and private insurance to pay for certain social goods. Where the financing for social goods is fragmented and overlapping, as it is for health and social care, joint financing PPPs may help organize existing financing streams. This piece argues that partnerships of this type also present an opportunity for consumer-protective regulation of the insurance industry if certain conditions are met. Private insurers must perceive benefits to the partnership, government actors must be motivated to protect the government’s financial stake, and government interests must align with those of consumers. It uses the Medicaid Partnership for Long-Term Care to illustrate the argument

Legal Age

How old are you? This deceptively simple question has a clear answer in the law, which is a number measuring the amount of time that has elapsed since birth. However, as scientists discover various biomarkers of human aging and individuals openly embrace more fluid identities, this chronological definition will soon have to compete with biological and subjective alternatives. Legal scholars have previously examined the role of age in the legal system, but they have done so assuming a chronological definition. This is the first Article to examine critically the antecedent question of how we should define legal age after one has reached adulthood. The stakes for this definition are high. Age is ubiquitous in the legal landscape, appearing in the Constitution, antidiscrimination statutes, criminal laws, and public benefits programs. This Article normatively assesses the chronological, biological, and subjective conceptions of age, examining how well they improve the accuracy of the legal system, impact administrative costs, promote autonomy interests, and further antisubordination goals. It then charts three potential paths forward for legal age: abolishing age as a meaningful legal category for adults, particularizing the definition of legal age based on context, and reforming the chronological status quo through the calibration of existing age-based law

Newsgathering in Light of HIPAA

This short piece examines the interaction between the Health Insurance Portability and Accountability Act (HIPAA), a federal law designed to protect the privacy of individuals’ health information, and state Freedom of Information (FOI) laws, which are designed to ensure public access to government documents. It describes three recent cases from different states that addressed difficult issues about where and how to draw the line between the public’s right to know and individuals’ rights to keep their medical information secret. It concludes that questions about the interaction of state FOI laws and HIPAA should be guided by the framework suggested in HIPAA regulations for understanding the interaction between HIPAA and the federal Freedom of Information Act. State courts and agencies should therefore use the provisions in state FOI laws that regard medical privacy to inform decisions about information requests from citizens and the media