Modifiable risk factors remain significant causes of medium term mortality after first time Coronary artery bypass grafting

<p>Abstract</p> <p>Background</p> <p>Whilst there is much current data on early outcomes after Coronary artery bypass grafting(CABG), there is relatively little data on medium term outcomes in the current era. The purpose of this study is to present a single surgeon series comprising of all first time CABG patients operated on with the technique of cross clamp fibrillation from Feb-1996 to through to Jan-2003, and to seek risk factors for medium term mortality in these patients.</p> <p>Methods</p> <p>Data was collected from Hospital Episode Statistics and departmental patient administration and tracking systems and cross checked using database techniques. Patient outcomes were searched using the National Health Service strategic tracing service.</p> <p>Results</p> <p>Mean follow up was 5.3 years(0–9.4 years) and was complete for all patients. 30-day survival was 98.4%, 1-year survival 95% and 8-year survival 79%. Cox-regression analysis revealed that several modifiable pre-operative risk factors remain significant predictors of medium term mortality, including Diabetes(Hazard Ratio(HR) 1.73, 95%CI 1.21–2.45), Chromic obstructive pulmonary disease(HR 2.02, 95%CI 1.09–3.72), Peripheral vascular disease(HR 1.68, 95%CI 1.13–2.5), Body mass index>30(HR 1.54, 95%CI 1.08–2.20) and current smoker at operation(HR 1.67, 95%CI 1.03–2.72). However hypertension(HR 1.31, 95%CI 0.95–1.82) and Hypercholestrolaemia(HR 0.81, 95%CI 0.58–1.13) were not predictive which may reflect adequate post-operative control.</p> <p>Conclusion</p> <p>Coronary artery bypass surgery using cross clamp fibrillation is associated with a very low operative mortality. Medium term survival is also good but risk factors such as smoking at operation, Chronic obstructive pulmonary disease, obesity and diabetes negatively impact this survival and should be aggressively treated in the years post-surgery.</p

Pairing People with Products: Anthropomorphizing the Object, Dehumanizing the Person

We present the first empirical integration of anthropomorphism and dehumanization, two intrinsically linked processes representing the extent to which the concept of humanness is activated for a given target. Across several experiments, we demonstrate that pairing a person and object in an ad, while focusing respondent attention on the object, leads to its being anthropomorphized and evaluated better compared to presenting it alone. However, compared to presenting a person alone, the same pairing leads to inferior evaluations of the person through a process of dehumanization. We rule out two alternative explanations for these effects, namely the transfer of an object’s qualities to the person and consumption associations, and conduct a post-test that provides additional support for our proposed activation/inhibition of humanness account. Finally, we inspect several moderators, finding that anthropomorphism only occurs with moderately and highly functional objects and dehumanization occurs irrespective of the person’s gender or fame. By incorporating the literature on dehumanization, we propose new research questions to motivate future inquiry