Configuration and hindcast quality assessment of a brazilian global sub‐seasonal prediction system

This paper presents the Center for Weather Forecast and Climate Studies (CPTEC) developments for configuring a global sub-seasonal prediction system and assessing its ability in producing retrospective predictions (hindcasts) for meteorological conditions of the following 4 weeks. Six Brazilian Global Atmospheric Model version 1.2 (BAM-1.2) configurations were tested in terms of vertical resolution, deep convection and boundary layer parameterizations, as well as soil moisture initialization. The aim was to identify the configuration with best performance when predicting weekly accumulate precipitation, weekly mean 2-meter temperature (T2M) and the Madden and Julian Oscillation (MJO) daily evolution. Hindcasts assessment was performed for 12 extended austral summers (November to March - 1999/2000 to 2010/2011) with two start dates for each month for the six configurations and two ensemble approaches. The first approach, referred to as Multiple Configurations Ensemble (MCEN), was formed of one ensemble member from each of the six configurations. The second, referred to as Initial Condition Ensemble (ICEN), was composed of six ensemble members produced with the chosen configuration as the best using an Empirical Orthogonal Function (EOF) perturbation methodology. The chosen configuration presented high correlation and low root mean squared error (RMSE) for precipitation and T2M anomaly predictions at the first week and these indices degraded as lead time increased, maintaining moderate performance up to week 4 over the tropical Pacific and northern South America. For MJO predictions, this configuration crossed the 0.5 bivariate correlation threshold in 18 days. The ensemble approaches improved the correlation and RMSE of precipitation and T2M anomalies. ICEN improved precipitation and T2M predictions performance over eastern South America at week 3 and over northern South America at week 4. Improvements were also noticed for MJO predictions. The time to cross the above mentioned threshold increased to 21 days for MCEN and to 20 days for ICEN

Evaluation of climate simulations produced with the Brazilian Global Atmospheric Model version 1.2

This paper presents an evaluation of climate simulations produced by the Brazilian Global Atmospheric Model version 1.2 (BAM-1.2) of the Center for Weather Forecast and Climate Studies (CPTEC). The model was run over the 1975-2017 period at two spatial resolutions, corresponding to ~180 and ~100 km, both with 42 vertical levels, following most of the Atmospheric Model Intercomparison Project (AMIP) protocol. In this protocol, observed sea surface temperatures (SSTs) are used as boundary conditions for the atmospheric model. Four ensemble members were run for each of the two resolutions. A series of diagnostics was computed for assessing the model's ability to represent the top of the atmosphere (TOA) radiation, atmospheric temperature, circulation and precipitation climatological features. The representation of precipitation interannual variability, El Niño-Southern Oscillation (ENSO) precipitation teleconnections, the Madden and Julian Oscillation (MJO) and daily precipitation characteristics was also assessed. The model at both resolutions reproduced many observed temperature, atmospheric circulation and precipitation climatological features, despite several identified biases. The model atmosphere was found to be more transparent than the observations, leading to misrepresentation of cloud-radiation interactions. The net cloud radiative forcing, which produces a cooling effect on the global mean climate at the TOA, was well represented by the model. This was found to be due to the compensation between both weaker longwave cloud radiative forcing (LWCRF) and shortwave cloud radiative forcing (SWCRF) in the model compared to the observations. The model capability to represent inter-annual precipitation variability at both resolutions was found to be linked to the adequate representation of ENSO teleconnections. However, the model produced weaker than observed convective activity associated with the MJO. Light daily precipitation over the southeast of South America and other climatologically similar regions was diagnosed to be overestimated, and heavy daily precipitation underestimated by the model. Increasing spatial resolution helped to slightly reduce some of the diagnosed biases. The performed evaluation identified model aspects that need to be improved. These include the representation of polar continental surface and sea ice albedo, stratospheric ozone, low marine clouds, and daily precipitation features, which were found to be larger and last longer than the observed features

A perspective for advancing climate prediction services in Brazil

The Climate Science for Service Partnership Brazil (CSSP-Brazil) project provides Brazil and UK partners the opportunity to address important challenges faced by the climate modeling community, including the need to develop subseasonal and seasonal prediction and climate projection services. This paper provides an overview of the climate modeling and prediction research conducted through CSSP-Brazil within the context of a framework to advance climate prediction services in Brazil that includes a research-to-services (R2S) and a services-to-research (S2R) feedback pathway. The paper also highlights plans to advance scientific understanding and capability to produce beneficial climate knowledge and new products to improve climate prediction services to support decisions in various industries in Brazil. Policy-relevant outcomes from climate modeling and prediction exercises illustrated in this paper include supporting stakeholders with climate information provided from weeks to months ahead for (a) improving water management strategies for human consumption, navigation, and agricultural and electricity production; (b) defining crop variety and calendars for food production; and (c) diversifying energy production with alternatives to hydropower

Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare inflammatory disease of unknown cause. 30% of patients have anti-neutrophil cytoplasmic antibodies (ANCA) specific for myeloperoxidase (MPO). Here, we describe a genome-wide association study in 676 EGPA cases and 6,809 controls, that identifies 4 EGPA-associated loci through conventional case-control analysis, and 4 additional associations through a conditional false discovery rate approach. Many variants are also associated with asthma and six are associated with eosinophil count in the general population. Through Mendelian randomisation, we show that a primary tendency to eosinophilia contributes to EGPA susceptibility. Stratification by ANCA reveals that EGPA comprises two genetically and clinically distinct syndromes. MPO+ ANCA EGPA is an eosinophilic autoimmune disease sharing certain clinical features and an HLA-DQ association with MPO+ ANCA-associated vasculitis, while ANCA-negative EGPA may instead have a mucosal/barrier dysfunction origin. Four candidate genes are targets of therapies in development, supporting their exploration in EGPA

Analysis of the common genetic component of large-vessel vasculitides through a meta- Immunochip strategy

Giant cell arteritis (GCA) and Takayasu's arteritis (TAK) are major forms of large-vessel vasculitis (LVV) that share clinical features. To evaluate their genetic similarities, we analysed Immunochip genotyping data from 1,434 LVV patients and 3,814 unaffected controls. Genetic pleiotropy was also estimated. The HLA region harboured the main disease-specific associations. GCA was mostly associated with class II genes (HLA-DRB1/HLA-DQA1) whereas TAK was mostly associated with class I genes (HLA-B/MICA). Both the statistical significance and effect size of the HLA signals were considerably reduced in the cross-disease meta-analysis in comparison with the analysis of GCA and TAK separately. Consequently, no significant genetic correlation between these two diseases was observed when HLA variants were tested. Outside the HLA region, only one polymorphism located nearby the IL12B gene surpassed the study-wide significance threshold in the meta-analysis of the discovery datasets (rs755374, P?=?7.54E-07; ORGCA?=?1.19, ORTAK?=?1.50). This marker was confirmed as novel GCA risk factor using four additional cohorts (PGCA?=?5.52E-04, ORGCA?=?1.16). Taken together, our results provide evidence of strong genetic differences between GCA and TAK in the HLA. Outside this region, common susceptibility factors were suggested, especially within the IL12B locus

A genome-wide association study identifies risk alleles in plasminogen and P4HA2 associated with giant cell arteritis

Giant cell arteritis (GCA) is the most common form of vasculitis in individuals older than 50 years in Western countries. To shed light onto the genetic background influencing susceptibility for GCA, we performed a genome-wide association screening in a well-powered study cohort. After imputation, 1,844,133 genetic variants were analysed in 2,134 cases and 9,125 unaffected controls from ten independent populations of European ancestry. Our data confirmed HLA class II as the strongest associated region (independent signals: rs9268905, P = 1.94E-54, per-allele OR = 1.79; and rs9275592, P = 1.14E-40, OR = 2.08). Additionally, PLG and P4HA2 were identified as GCA risk genes at the genome-wide level of significance (rs4252134, P = 1.23E-10, OR = 1.28; and rs128738, P = 4.60E-09, OR = 1.32, respectively). Interestingly, we observed that the association peaks overlapped with different regulatory elements related to cell types and tissues involved in the pathophysiology of GCA. PLG and P4HA2 are involved in vascular remodelling and angiogenesis, suggesting a high relevance of these processes for the pathogenic mechanisms underlying this type of vasculitis

Weather forecasts and climate prediction at CPTEC

Numerical weather forecasts and climate predictions have been performed at CPTEC since 1995 using the spectral numerical global circulation model, CPTEC/COLA AGCM with T62L28 resolution. Due to the chaotic behaviour of the atmosphere, it is desirable that a prediction be a result of several integrations with different initial conditions. The technique of ensemble prediction reduces the impact of the initial condition uncertainty on the final result. In climate prediction the initial sates are given by conditions of consecutive days. However, in weather forecast there are several methods to generate the initial conditions which must represent the initial uncertainty of the analysis field. In this paper the ensemble prediction system used at CPTEC is shown for both weather forecast and climate prediction.Pages: on lin

An analysis of daily maximum wind speed in Northwestern Europe using generalized models

Using monthly mean data, daily data, and theoretical arguments, relationships between surface pressure variations associated with the North Atlantic Oscillation (NAO), tropopause height, and the strength of the stratospheric vortex are established. An increase in the NAO index leads to a stronger stratospheric vortex, about 4 days later, as a result of increased equatorward refraction of upward-propagating Rossby waves. At tropopause level the effects of the enhanced NAO index and stratospheric polar vortex are opposite, resulting in a lower tropopause over Iceland and a higher tropopause over the Arctic. The raising of the Arctic tropopause leads to a stretching and spinup of the tropospheric column and is therefore associated with a lowering of the surface pressure near the North Pole. For monthly mean data it is found that a standard deviation increase in the NAO index is associated with a 10% increase in the strength of the stratospheric vortex, as measured by potential vorticity at 500 K. A simple theoretical model predicts that this is associated with about 300-m elevation of the Arctic tropopause, as is observed, and a 5-hPa lowering of the surface pressure at the North Pole. The effects of the spinup of the tropospheric column may project on the NAO pattern so that the stratosphere acts as an integrator of the NAO index

AMOC decline and recovery in a warmer climate

Abstract This study presents novel insight into the mechanisms of Atlantic Meridional Overturning Circulation (AMOC) reduction and its recovery under a warmer climate scenario. An one-thousand-year-long numerical simulation of a global coupled ocean–ice–atmosphere climate model, subjected to a stationary atmospheric radiative forcing, depict a coherent picture of the Arctic sea ice melting as a trigger for the initial AMOC reduction, along with decreases in the northward fluxes of salt and heat. Further atmospheric-driven ocean processes contribute to an erosion of the stable stratification of the fresher, yet colder waters in the surface layers of the North Atlantic, contributing to the recovery of a permanently altered AMOC

Assessing the representation of South American monsoon features in Brazil and UK climate model simulations

This paper assesses how well the CPTEC/INPE Brazilian Global Atmospheric Model (BAM-1.2) and the atmospheric component of the UK Met Office Hadley Centre Global Environment Model (HadGEM3-GC3.1) represent the main South American monsoon features. Climatological (1981–2010) ensemble means of Atmospheric Model Intercomparison Project (AMIP)-type climate simulations are evaluated. The assessment evaluated the models’ ability to represent the South America austral summer and winter precipitation contrast and associated circulation, key South American monsoon system elements, the association between south-east Brazil and South America precipitation, and climatological (1997/1998 to 2013/2014) distributions of rainy season onset and demise dates over south-east Brazil (15°S–25°S, 40°W–50°W) and the core monsoon region (10°S–20°S, 45°W–55°W). Despite some identified deficiencies, both models depict the monsoon region and represent the main features, including (1) the north-west–south-east precipitation band and associated ascending motion over central South America; (2) the upper-level Bolivian High and the north-east South America trough during the summer; (3) the lower-level South Atlantic and Pacific subtropical anti-cyclones and (4) the low-level jet east of the Andes. Both models represent upper-level divergence and lower-level convergence over the core monsoon region, and upper-level convergence and lower-level divergence over the Pacific and Atlantic anti-cyclones associated with the regional Walker circulation during the pre-monsoon (spring) and peak monsoon (summer) seasons. Convection over South America is weaker in BAM-1.2 than observed, consistent with continental precipitation deficit. The models reproduce the dipole-like precipitation pattern between south-east Brazil and south-eastern South America during the austral summer but overestimate these patterns spatial extent over the South Atlantic. Both models simulate the main observed climatological features of rainy season onset and demise dates for the two above defined investigated regions. HadGEM3 overestimates onset dates interannual variability. These results can contribute towards understanding climate and land-use change implications for environmental sustainability and for recommending climate adaptation strategies