2 research outputs found
Therapeutic Anticoagulant Does not Modify Thromboses Rate Vein after Venous Reconstruction Following Pancreaticoduodenectomy
Recommendations for anticoagulation following major venous
reconstruction for pancreatic adenocarcinoma (PA) are not clearly
established. The aim of our study was to find out the relation
between postoperative anticoagulant treatment and thrombosis rate
after portal venous resection. Materials and methods. Between 1986
and 2006, twenty seven portal vein resections were performed
associated with pancreaticoduodenectomies (n = 27) (PD).We defined
four types of venous resection: type I was performed 1 cm above
the confluent of the superior mesenteric vein (SMV) (n = 12); type
II lateral resection and venorrhaphy at the level of the
confluent SMV (n = 12); type III (n = 1) resulted from a primary
end-to-end anastomosis above confluent and PTFE graph was used for
reconstruction for type IV (n = 2). Curative anticoagulant treatment
was always indicated after type IV (n = 2) resection, and after
resection of type II when the length of venous resection was
longer than ≥2 cm. Results. Venous thrombosis rate reached: 0%,
41%, and 100% for type I, II, IV resections, respectively. Among
them four patients received curative anticoagulant treatment.
Conclusion. After a portal vein resection was achieved in the
course of a PD, curative postoperative anticoagulation does not
prevent efficiently the onset of thrombosis