59 research outputs found
Origin and Detection of Microstructural Clustering in Fluids with Spatial-Range Competitive Interactions
Fluids with competing short-range attractions and long-range repulsions mimic
dispersions of charge-stabilized colloids that can display equilibrium
structures with intermediate range order (IRO), including particle clusters.
Using simulations and analytical theory, we demonstrate how to detect cluster
formation in such systems from the static structure factor and elucidate links
to macrophase separation in purely attractive reference fluids. We find that
clusters emerge when the thermal correlation length encoded in the IRO peak of
the structure factor exceeds the characteristic lengthscale of interparticle
repulsions. We also identify qualitative differences between the dynamics of
systems that form amorphous versus micro-crystalline clusters.Comment: 6 pages, 5 figure
A quantum phase gate implementation for trapped ions in thermal motion
We propose a novel scheme to implement a quantum controlled phase gate for
trapped ions in thermal motion with one standing wave laser pulse. Instead of
applying the rotating wave approximation this scheme makes use of the
counter-rotating terms of operators. We also demonstrate that the same scheme
can be used to generate maximally entangled states of trapped ions by a
single laser pulse
Short-term, high-fat diet accelerates disuse atrophy and protein degradation in a muscle-specific manner in mice
Background:
A short-term high-fat diet impairs mitochondrial function and the ability of skeletal muscle to respond to growth stimuli, but it is unknown whether such a diet alters the ability to respond to atrophy signals. The purpose of this study was to determine whether rapid weigh gain induced by a high-fat (HF) diet accelerates denervation-induced muscle atrophy.
Methods:
Adult, male mice (C57BL/6) were fed a control or HF (60Ă‚Â % calories as fat) diet for 3Ă‚Â weeks (3wHF). Sciatic nerve was sectioned unilaterally for the final 5 or 14Ă‚Â days of the diet. Soleus and extensor digitorum longus (EDL) muscles were removed and incubated in vitro to determine rates of protein degradation and subsequently homogenized for determination of protein levels of LC3, ubiquitination, myosin heavy chain (MHC) distribution, and mitochondrial subunits.
Results:
When mice were fed the 3wHF diet, whole-body fat mass more than doubled, but basal (innervated) muscle weights, rates of protein degradation, LC3 content, mitochondrial protein content, and myosin isoform distribution were not significantly different than with the control diet in either soleus or EDL. However in the 14Ă‚Â day denervated soleus, the 3wHF diet significantly augmented loss of mass, proteolysis rate, amount of the autophagosome marker LC3 II, and the amount of overall ubiquitination as compared to the control fed mice. On the contrary, the 3wHF diet had no significant effect in the EDL on amount of mass loss, proteolysis rate, LC3 levels, or ubiquitination. Fourteen days denervation also induced a loss of mitochondrial proteins in the soleus but not the EDL, regardless of the diet.
Conclusions:
Taken together, a short-term, high-fat diet augments denervation muscle atrophy by induction of protein degradation in the mitochondria-rich soleus but not in the glycolytic EDL. These findings suggest that the denervation-induced loss of mitochondria and HF diet-induced impairment of mitochondrial function may combine to promote skeletal muscle atrophy
Kentucky Labor Supply and Demand Surveys
Excerpt from the executive summary:
The Center for Business and Economic Research at the University of Kentucky (CBER), along with its partners, the Survey Research Center at the University of Kentucky (UK-SRC), the Survey Research Center in the Urban Studies Institute at the University of Louisville (UL-SRC), and the Department of Economics at the University of Louisville, is pleased to present this final report on the findings of the Kentucky labor supply and demand surveys sponsored by the Kentucky Cabinet for Workforce Development. The two universities have put together a consortium including some of the best scholars in the region in the areas of labor economics, local economic development, and survey design and administration
The Grizzly, October 9, 2003
Choose to Reuse: Recycling at Ursinus • Volunteer Program Breaks the Bank • Get Registered to Get Out the Vote • Meet the Democratic Candidates for President • A Look at the Response to Rape at Ursinus • Opinions: How Safe do we Feel?; Out of the Middle East: End of a Journey; Text Messaging Behind Your S.O.\u27s Back; New Addiction: AIM; Domo Arigato, Dr. Roboto • Guster: Having Fun Being Young • Halloween Fun Around Collegeville • The Eger Gateway • Field Hockey Still Undefeated in Conference Play • Ursinus XC Takes on Div. 1 and 2 Opponents • Volleyball Splits First C.C Matches • Women\u27s Soccer Continues to Impress • Men\u27s Soccer Trying to Battle • Josh Kemp: Changing the Record Bookshttps://digitalcommons.ursinus.edu/grizzlynews/1544/thumbnail.jp
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