Left Atrial Paraganglioma in a Dog: Echocardiography, Surgery, and Scintigraphy

Primary tumors of the left atrium are uncommon in dogs and tumor-specific diagnoses have been made only at necropsy. No reports have been found in which the diagnosis was confirmed antemortem and the tumor removed surgically. This report describes a case of obstructive paraganglioma in the left atrium of a dog and long-term survival after surgical removal of most of the tumor using cardiopulmonary bypass. Subsequently, scintigraphy demonstrated the presence of somatostatin receptors in residual tumor in the left atrium. The latter technique may be of value in establishing a definitive diagnosis in future cases of chemodectoma, extra-adrenal paraganglioma, or adrenal paraganglioma (phechromocytoma)

Nutrient digestibility of 44% soybean meal, extruded whole soybeans, and an extruded soybean mixture for growing-finishing swine

Due to the character of the original source materials and the nature of batch digitization, quality control issues may be present in this document. Please report any quality issues you encounter to [email protected], referencing the URI of the item.Bibliography: leaves 36-39.Not availabl

Tomato Growth, Yield and Quality Response to Mixed Chemical-Organic Fertilizers and Grafting Treatments in High Tunnel Environment

Tomato (Solanum lycopersicum L.) is a major vegetable crop world-wide, and grown in high tunnels in many regions. This study investigates the use of two fertilizer sources, chemical and integrated (composted poultry manure plus urea) fertilizers, and grafting on growth, nitrate-N content, yield, and fruit quality of tomato grown in high tunnels in northwestern Washington. Grafting treatments consisted of ‘Panzer’ tomato grafted on one of three tomato rootstocks ‘Estamino’, Maxifort’, ‘DRO138TX’, or non-grafted (control). Application of chemical fertilizer increased number of leaves per plant, plant height, and cumulative fresh biomass of pruned suckers relative to tomato plants grown with the integrated fertilizer treatment. Grafted tomato plants had greater plant growth than non-grafted plants throughout the growing season. There was no significant difference between fertilizer treatments on nitrate-N concentration in plant tissue or fresh petiole sap; however, grafted plants contained higher levels of nitrate-N than non-grafted plants. Total and marketable fruit weight and number did not differ due to fertilizer source, but total and marketable fruit weight was higher for grafted plants than for non-grafted plants in 2016. There was no significant effect due to fertilizer source on fruit firmness, water content, pH, titratable acidity, and β-carotene; however, total soluble solids (TSS) and lycopene content were higher for fruit grown with integrated fertilizer in 2016. Grafting enhanced water content of tomato fruit in 2015, and TSS (Brix) in 2016.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author

Aggregated n-of-1 trials of central nervous system stimulants versus placebo for paediatric traumatic brain injury: a pilot study

Background: In 2006 there were 432,700 people in Australia who had acquired brain injury (ABI) with some limitation of activities; 90% of these were traumatic brain injuries (TBIs) and nearly a third sustained injury below age 15 years. One to four years post injury, 20% to 46% of children with traumatic brain injury (TBI) have clinically significant disorders of attention. There is controversy as to whether central nervous system (CNS) stimulants can be an effective method of treating these

Effects of once-weekly exenatide on cardiovascular outcomes in type 2 diabetes

BACKGROUND: The cardiovascular effects of adding once-weekly treatment with exenatide to usual care in patients with type 2 diabetes are unknown. METHODS: We randomly assigned patients with type 2 diabetes, with or without previous cardiovascular disease, to receive subcutaneous injections of extended-release exenatide at a dose of 2 mg or matching placebo once weekly. The primary composite outcome was the first occurrence of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke. The coprimary hypotheses were that exenatide, administered once weekly, would be noninferior to placebo with respect to safety and superior to placebo with respect to efficacy. RESULTS: In all, 14,752 patients (of whom 10,782 [73.1%] had previous cardiovascular disease) were followed for a median of 3.2 years (interquartile range, 2.2 to 4.4). A primary composite outcome event occurred in 839 of 7356 patients (11.4%; 3.7 events per 100 person-years) in the exenatide group and in 905 of 7396 patients (12.2%; 4.0 events per 100 person-years) in the placebo group (hazard ratio, 0.91; 95% confidence interval [CI], 0.83 to 1.00), with the intention-to-treat analysis indicating that exenatide, administered once weekly, was noninferior to placebo with respect to safety (P<0.001 for noninferiority) but was not superior to placebo with respect to efficacy (P=0.06 for superiority). The rates of death from cardiovascular causes, fatal or nonfatal myocardial infarction, fatal or nonfatal stroke, hospitalization for heart failure, and hospitalization for acute coronary syndrome, and the incidence of acute pancreatitis, pancreatic cancer, medullary thyroid carcinoma, and serious adverse events did not differ significantly between the two groups. CONCLUSIONS: Among patients with type 2 diabetes with or without previous cardiovascular disease, the incidence of major adverse cardiovascular events did not differ significantly between patients who received exenatide and those who received placebo