Periodontal Tissue Reaction Consecutive Implantation of Endodontic Materials and Subsequent Integration of Complex Oral Rehabilitation Treatments

Oral rehabilitation is a main branch of dentistry focused on diagnosing the patient’s problem and creating a treatment plan to restore aesthetics, recondition morphologically all components, and recover the functionality of the oral cavity. Biological compatibility of the materials used has a major importance, due to the direct contact with essential tissues, such as the soft and hard tissue of the periodontium and the potential influence on the outcome of the treatment. The present material aims to assess the inflammatory response after subcutaneous implantation of three materials frequently used in endodontics (Mineral Trioxide Aggregate—MTA, DiaRoot BioAggregate, and Sealapex). The evaluation of the reparative tissue reaction after 7, 30, and 60 days, respectively, subsequent to in vivo implantation, was carried out through electron microscopy imaging. Moreover, evaluation of the dynamics of the osteogenesis process was an indicator for the maintenance of internal homeostasis in the context of complex intraoral rehabilitation treatments that include fixed prosthodontics correlated with the particular periodontal-aesthetic aspects and completed by cranio-mandibular repositioning. Our study showed increased absolute values of alkaline phosphatase in all material-implanted cases (more pronounced in MTA and Bio Aggregate), highlighting that this enzyme could be an effective indicator of bone formation, which takes place after the material implantation, with the most significant elevated values at 30 days postoperatively

Modification of Salivary Proteins, Glucose and Calcium Level in General Diseases

Biochemical analysis of the inorganic salivary compounds can serve as indicators of salivary gland modifications during some general diseases, with repercussions on the cariogenic risk. The aim of the study was to evaluate the modification of some salivary parameters in different conditions of general affection (high blood pressure associated with diabetes and radiotherapy). Materials and methods The study was conducted on 65 patients aged between 65 to 80 years old. The values of total salivary proteins, salivary glucose and calcium-Ca2+, that could influence the occurrence of some oral cavity modifications, as a result of the pre-existing systemic pathology, were determined. Results The study showed that there are no significant variations of total proteins at the studied patients. We found elevated salivary glucose levels in patients with high blood pressure associated with diabetes and an increase of calcium concentration in patients which received radiotherapy. Conclusion The presence of high blood pressure associated with diabetes, and the radiation treatment affects quality of oral fluid

Modification of Some Salivary Parameters in Different General States of Disease

Salivary modifications can be the most often oral expression of systemic disease. The aim of the study was to evaluate certain modifications of some salivary parameters in different general affecting conditions. Materials and methods Base salivary flow, stimulated salivary flow and pH were evaluated on 27 patients with high blood pressure and diabetes, 23 with radiotherapy treatment and 15 with general satisfactory clinic condition. Results All the evaluated indicators were lower compared to the control group study. Conclusion Both medication and radiotherapy treatment affect the salivary glands inducing changes in the quality and quantity of oral fluid

An Observational Study on Oral Health and Quality of Life for RPD Wearers in the N-E Region of Romania

There is a lack of information regarding the oral health of the elderly population in Romania; only a few articles have been published about their edentulism, and there are no official data regarding the oral health, OHRQoL, and prosthodontic status of this population. The objective of this study was to assess the relationship between the essential functional qualities of removable partial dentures (RPD) and participants’ oral-health-related wellbeing among an edentulous population from the N-E region in Romania using the OHIP-5-questionnaire. In total, 546 patients from Gr. T. Popa Iasi University were enrolled after following a set of sorting procedures. We used the Kruskal–Wallis test and the Mann–Whitney test to determine whether there were significant differences between the various groups of patients. For questions 1, 2, 3, and 5 of the OHIP, the null hypothesis was rejected, as there were statistically significant differences between the three groups. This study was limited to a specific group. However, it can provide an insight into RPD patients’ happiness when treated in an academic environment

Research Regarding Dental Mobility Phenomena in the Clinical Recognition Diagnosis of Temporomandibular Disorders

The main objective of this study is to quantify the implications of the complications of periodontal pathology and dental mobility on the pathology of dysfunctional algo syndrome, a clinical entity with profound implications for the patient’s quality of life. Methodology: Clinical and laboratory evaluation was conducted in the 2018–2022 period, on a group of 110 women and 130 men, aged between 20–69, selected from our practice venue, Policlinica Stomatologica nr. 1 Iasi, Clinical Base of Dentistry Education “Mihail Kogalniceanu” Iasi, “Grigore T. Popa” University of Medicine and Pharmacy Iasi and “Apollonia” University Iasi. Overall, 125 subjects were diagnosed with periodontal disease with complications and TMJ disorders and followed periodontal therapy in the context of oral complex rehabilitation treatments (study group); the results of their clinical evaluation were compared with the results of the evaluation of the control group, made from the other 115 patients). Results: Dental mobility and gingival recession were identified as more frequent in the study sample compared with the control sample, the differences being statistically significant in both cases. In total, 26.7% of patients had different types of TMJ disorders and 22.9% of patients had occlusal changes; the percentages are slightly increased in the study sample compared with the control one, but the recorded differences are not statistically significant. Conclusions: Dental mobility, most of the time, is a negative consequence of periodontal disease, leading to the alteration of the mandibular-cranial relations, materializing in an important proportion as an etiopathogenic factor of the dysfunctional syndrome of the stomatognathic system

[WITHDRAWN] Interdisciplinarity in Complex Therapeutic Approach of Psychiatric Patients with Dysfunctional Syndrome of the Stomatognated System

Diseases in the maxillofacial sphere and especially the dysfunctional syndrome of the stomatognathic system have many connections and interferences with the psychiatric pathology and why not last, but not least the appearance and aesthetics that have an impact on social life and success. On the other hand, there has been a significant increase in the use of antipsychotics in recent decades. The negative impact on oral health has also increased. The ability to diagnose mental illness is essential due to the social stigma associated with these disorders and a correct differential diagnose as well. This article describes the oro-dental rehabilitation of one case, psychiatrically treated, with mandibular and maxilla missing teeth and dental destruction and prosthetic damage, temporomandibular disorders pathology due to the disbalanced occlusion and depression and anxiety, with specific medication, fixed and removable hybrid prosthesis and intra oral complex rehabilitation.Editor's Note | On 27.11.2023 the authors requested the paper withdrawal. Based on their request, the case is sent into analysis to the LUMEN Committee of Research and Publication Ethics. A decision on this case will be available online soon.Later edit | 15.12.2023 : The publisher requested each author to confirm by email its willingness to withdraw the paper from publication. Based on all the authors' confirmations the LUMEN Committee of Research and Publication Ethics will be able to finish its analysis and give a final decision.Decision | 15.01.2024: Based on the analysis of the authors' requests and the case information, the LUMEN Committee for Research and Publication Ethics decided the paper retraction. The retraction was based on duplicate publication.</p

The Quantification of Salivary Flow and pH and Stomatognathic System Rehabilitation Interference in Patients with Oral Diseases, Post-Radiotherapy

Xerostomia is a common complication post-radiotherapy in patients with oral cancer. The acute and long-term side effects can considerably reduce the patient’s quality of life. The aim of our study was to perform analysis of salivary flow and pH in patients after radiotherapy. Methodology: Clinical and laboratory evaluations were conducted in the 2014–2019 period; out of a total 58 subjects aged between 45 and 84, 28 individuals with oral cancer were selected from St. Spiridon Hospital, Clinic of Maxillo-facial Surgery and Oncology Hospital, Iasi post-radiotherapy. Results: Significant downsized mean values of the hydrogen ion concentration (pH) in saliva (p < 0.001) were recorded in patients after radiotherapy, pH value = 4.580 (±1.051). The mean value of resting salivary flow (MRSF) was significantly lower for the group of patients with radiotherapy (MRSF) = 0.145 mL/min. In 89.29% of cases (25 post-radiotherapy cases), in order to perform oral complex rehabilitation treatment, several endodontic and periodontal treatments were performed. A total of 78.57% of the cases received complex oral rehabilitation as mobile or hybrid prostheses or fixed solutions. Conclusion: Understanding post-radiotherapy salivary biochemic modifications in patients with oral cancer could be of critical importance, in view of related oral disorder prevention

A Retrospective Clinical Trial Regarding Oral Rehabilitation Diagnosis Strategies Based on Stomatognathic System Pathology

Introduction: Orofacial pain is a common occurrence in daily dental practice; it is frequently attributed to temporomandibular dysfunction, one of its major causes, followed by pathology of the salivary glands, without avoiding interference at the level of the pain pathways caused by complications of periodontal pathology. The main objective of this study is to identify an important cause of pain in the oral–maxillofacial territory by quantifying the changes at the salivary glandular level using stereological methods. The secondary objective of the present research is to identify the implications of periodontal changes as a consequence of salivary quantitative and qualitative changes, quantified using periodontal indices, on the balance of the temporomandibular joint, dysfunction of it being an important cause of facial pain and having a profound impact on the complex oral rehabilitation algorithm of each clinical case, a condition evaluated with the analysis of the results of the Souleroy questionnaire. Material and methods: In a retrospective study, we evaluated the clinical results obtained after applying complex rehabilitation treatment to 35 subjects, 20 women and 15 men with salivary and TMJ dysfunctions, selected between 2020 and 2021 from the Clinic of Maxillofacial Surgery, Iasi. Results and discussion: The most common symptoms of temporomandibular disorders (TMDs) that were identified through the Souleroy questionnaire were pain and different types of damage to the masticatory muscles. The most significant changes in elders are reported in the case of serous cells, which reduced their percentage volume from 46.7% to 37.4%. Conclusion: As regards stereological analysis in conjunction with histological images, there were significant changes in diameters, perimeters, and longitudinal axes in the adult patients as opposed to the elderly patients, which were also influenced by the type of pathology at this level. The scores recorded on the diagnostic Souleroy scale indicated a large number of patients with low efficiency and maximum stress levels: 20.0% in level 1, 25.7% in level 2, and 25.7% in level 3