An investigation of the high speed turbulent boundary layer with heat transfer and arbitrary pressure gradient. Part 1 - Summary report

Behavior of high speed turbulent boundary layer with heat transfer and streamwise pressure gradien

A mathematical model for jet engine combustor pollutant emissions

Mathematical modeling for the description of the origin and disposition of combustion-generated pollutants in gas turbines is presented. A unified model in modular form is proposed which includes kinetics, recirculation, turbulent mixing, multiphase flow effects, swirl and secondary air injection. Subelements of the overall model were applied to data relevant to laboratory reactors and practical combustor configurations. Comparisons between the theory and available data show excellent agreement for basic CO/H2/Air chemical systems. For hydrocarbons the trends are predicted well including higher-than-equilibrium NO levels within the fuel rich regime. Although the need for improved accuracy in fuel rich combustion is indicated, comparisons with actual jet engine data in terms of the effect of combustor-inlet temperature is excellent. In addition, excellent agreement with data is obtained regarding reduced NO emissions with water droplet and steam injection

An investigation of the high speed turbulent boundary layer with heat transfer and arbitrary pressure gradient. Part 3 - Computer program manual

Computer program for determining properties of high speed turbulent boundary layer with heat transfer and arbitrary pressure gradien

Initial hydrogen detonation data from the High-Temperature Combustion Facility

The Brookhaven National Laboratory High-Temperature Combustion Facility (HTCF) is described and data from initial hydrogen detonation experiments are presented. Initial phase of the inherent detonability experimental program is described. Test gases thus far tested are hydrogen-air mixtures at one atmosphere initial pressure and temperatures 300K-650K. Detonation pressure, wave speed, and detonation cell size were measured. Data were consistent with earlier SSDA (small-scale development apparatus) test results. HTCF results confirm the conclusion from the SSDA program that the gas temperature decreases the cell size and, therefore, increases the sensitivity of mixtures to detonation. Data from the larger HTCF test vessel, however, also demonstrates that the effect of increased scale is to extend the range of detonable mixtures to lower concentration

Cochlear implantation is safe and effective in patients with MYH9-related disease

Background: MYH9-related disease (MYH9-RD) is a rare syndromic disorder deriving from mutations in MYH9, the gene for the heavy chain of non-muscle myosin IIA. Patients present with congenital thrombocytopenia and giant platelets and have a variable risk of developing sensorineural deafness, kidney damage, presenile cataract, and liver abnormalities. Almost all MYH9-RD patients develop the hearing defect, which, in many individuals, progresses to severe to profound deafness with high impact on quality of life. These patients are potential candidates for cochlear implantation (CI), however, no consistent data are available about the risk to benefit ratio of CI in MYH9-RD. The only reported patient who received CI experienced perisurgery complications that have been attributed to concurrent platelet defects and/or MYH9 protein dysfunction. Methods: By international co-operative study, we report the clinical outcome of 10 patients with MYH9-RD and severe to profound deafness who received a CI at 8 institutions. Results: Nine patients benefited from CI: in particular, eight of them obtained excellent performances with restoration of a practically normal hearing function and verbal communication abilities. One patient had a slightly worse performance that could be explained by the very long duration of severe deafness before CI. Finally, one patient did not significantly benefit from CI. No adverse events attributable to MYH9-RD syndrome were observed, in particular no perisurgery bleeding complications due to the platelet defects were seen. Patients' perioperative management is described and discussed. Conclusions: CI is safe and effective in most patients with MYH9-RD and severe to profound deafness and should be offered to these subjects, possibly as soon as they develop the criteria for candidacy

Transferencia tecnológica, docencia e investigación de técnicas que utilizan isótopos estables en el área de la salud.

La utilización de isótopos estables se encuentra ampliamente difundida a nivel mundial, sin embargo, no son comúnmente utilizados en países en desarrollo debido al elevado costo de los isótopos estables y del equipamiento para su medición. La Universidad de Buenos Aires ha dado el primer paso en la utilización de éstas técnicas mediante la creación del Laboratorio de Isótopos Estables Aplicados a Biología y Medicina, en Noviembre de 2002. Dicho laboratorio fue creado en el contexto de los proyectos internacionales ARCAL LIV RLA-6042 y RLA 6054, subsidiados por el Organismo Internacional de Energía Atómica (OIEA) en cooperación con la Universidad de Buenos Aires. La instalación de un Espectrómetro de Masa y la puesta a punto del 13CTest del Aire Espirado para el diagnóstico de la infección por H. pylori permitió el desarrollo de proyectos de investigación relacionados con dicha bacteriay al mismo tiempo posibilitó la realización de servicios de transferencia tecnológica a entidades públicas y privadas a nivel nacional e internacional. En nuestra experiencia durante estos 12 años de trabajo, hemos realizado aproximadamente 18.000 determinaciones para el diagnóstico de la infección por H. pylori. Por otro lado, el espectrómetro de masa también es utilizado en diferentes actividades docentes de grado y posgrado. La promoción y armonización de estas nuevas metodologías isotópicas para la región ha sido nuestro primer desafío; para ello hemos implementado cursos regionales y pasantías para profesionales de diferentes países a través de la Secretaria de Ciencia y Técnica de la Facultad de Farmacia y Bioquímica de la Universidad de Buenos Aires. El objetivo de nuestro trabajo es presentar las metas y logros alcanzados por este laboratorio y su vinculación con la investigación, docencia y transferencia tecnológica en nuestro país.publishedVersio

Contrast sensitivity test and conventional and high frequency audiometry: information beyond that required to prescribe lenses and headsets

In Optometry and in Audiology, the routine tests to prescribe correction lenses and headsets are respectively the visual acuity test (the first chart with letters was developed by Snellen in 1862) and conventional pure tone audiometry (the first audiometer with electrical current was devised by Hartmann in 1878). At present there are psychophysical non invasive tests that, besides evaluating visual and auditory performance globally and even in cases catalogued as normal according to routine tests, supply early information regarding diseases such as diabetes, hypertension, renal failure, cardiovascular problems, etc. Concerning Optometry, one of these tests is the achromatic luminance contrast sensitivity test (introduced by Schade in 1956). Concerning Audiology, one of these tests is high frequency pure tone audiometry (introduced a few decades ago) which yields information relative to pathologies affecting the basal cochlea and complements data resulting from conventional audiometry. These utilities of the contrast sensitivity test and of pure tone audiometry derive from the facts that Fourier components constitute the basis to synthesize stimuli present at the entrance of the visual and auditory systems; that these systems responses depend on frequencies and that the patient's psychophysical state affects frequency processing. The frequency of interest in the former test is the effective spatial frequency (inverse of the angle subtended at the eye by a cycle of a sinusoidal grating and measured in cycles/degree) and, in the latter, the temporal frequency (measured in cycles/sec). Both tests have similar duration and consist in determining the patient's threshold (corresponding to the inverse multiplicative of the contrast or to the inverse additive of the sound intensity level) for each harmonic stimulus present at the system entrance (sinusoidal grating or pure tone sound). In this article the frequencies, standard normality curves and abnormal threshold shifts inherent to the contrast sensitivity test (which for simplicity could be termed "visionmetry") and to pure tone audiometry (also termed auditory sensitivity test) are analyzed with the purpose of contributing to divulge their ability to supply early information associated to pathologies not solely related to the visual and auditory systems respectively. © 2008 American Institute of Physics.Fil:Comastri, S.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.Fil:Martin, G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.Fil:Simon, J.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina

Glycine-Stabilized Zinc Gluconate has similar bioavailability than Zinc Sulfate in a zinc fortified probiotic food

Objective: In this study, we evaluated zinc gluconate stabilized with glycine (GZ) and sulfate (SZ) in fermented milk as vehicle. Zinc bioavailability was evaluated in an animal model (Sprague Dawley rats) for both zinc sources in the vehicle with a probiotic (Lactobacillus casei DN114001). Results: For growth parameters, higher weight gain and femur weight values were observed when probiotic and zinc were provided together, independent of the source (weight gain: SZ 81.4g±4.0g; GZ 81.8g±4.0g and 70.2g±12.5g without the probiotic; femur weight: SZ 0.51g ±0.05g; GZ 0.52g±0.05g and 0.42g±0.03g without the probiotic). Femur zinc content was higher for zinc gluconate stabilized with glycine in the presence of the probiotic (97.04ppm±8.40ppm), and the results were similar for zinc sulfate with or without probiotic (84.51ppm±2.44ppm and 84.94ppm±2.28ppm, respectively). Serum antioxidant capacity and immune cellular response were also evaluated by using free radical scavenging assays and a T cell proliferation assay respectively. The free radical scavenging assay showed a tendency to increase with zinc provision, and the highest proliferation index was observed for glycine-stabilized zinc gluconate and the probiotic. Conclusion: The results indicate that the combination of zinc (as glycine-stabilized zinc gluconate) and a probiotic may be beneficial for the evaluated parameters.Fil: Tesan, Fiorella Carla. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Fisicomatemática. Cátedra de Física; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Hernández, F.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Fisicomatemática. Cátedra de Física; ArgentinaFil: Torti, Horacio Emilio. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Fisicomatemática. Cátedra de Física; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Massot, Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Fisicomatemática. Cátedra de Física; ArgentinaFil: Huarte, M.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Fisicomatemática. Cátedra de Física; ArgentinaFil: Rubín de Celis, E.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Fisicomatemática. Cátedra de Física; ArgentinaFil: Barreiro Arcos, María Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos. Universidad de Buenos Aires. Facultad de Medicina. Centro de Estudios Farmacológicos y Botánicos; ArgentinaFil: Weill, R.. Danone Argentina S,a,; ArgentinaFil: Cremaschi, Graciela Alicia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos. Universidad de Buenos Aires. Facultad de Medicina. Centro de Estudios Farmacológicos y Botánicos; ArgentinaFil: Boccio, J.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Fisicomatemática. Cátedra de Física; ArgentinaFil: Salgueiro, María Jimena. Universidad de Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Approaches that will yield greater success when implementing self-administered electronic data capture ICT systems in the developing world with an illiterate or semi-literate population

The Information Technology (IT) Group at the Population Council responded to a need for a technology solution that would help researchers obtain more accurate responses to survey questions that concerned subject matter of a sensitive nature. The IT Group had three goals: (1) to enhance research by obtaining the best data possible, (2) to operate successfully in the local environment and be welcomed by the local populations, and (3) to increase the efficiency and cost-effectiveness of the survey process. This paper outlines approaches to consider when designing and implementing self-administered information and communications technology (ICT) questionnaires in developing countries, and reviews the problems and issues we encountered and how we overcame them. Many of the approaches outlined may also be used in general for ICT-related projects in the developing world. To meet future challenges, we have begun an effort to build a prototype system that would operate on a variety of devices—when connected to the internet or not (securely storing the data when the system is offline)—and provide an administrative application to step through simple screens to build a self-administered questionnaire with the most frequently used functions

The Trouble with Ed Schools: A Book Review

American schools of education, whose two primary objectives are to prepare highly qualified teachers and to conduct valid and reliable education research, are often decried as “weak institutions” by many in academia and society in general. American schools of education are very often scorned by scholars and academia as intellectually inferior, referred to by teachers in the field as the “ivory tower” and considered to be out of touch and completely unrelated to what really transpires in schools, perceived by political leaders at all levels to be a primary contributing factor to the substandard state of contemporary public education. These are the observations and assertions of David Labaree, a professor in the school of education at Stanford University, who in The Trouble with Ed Schools employs critical sociological and historical analyses to analyze and examine the factors that have directly contributed to the lowly status of education schools in general, and the contemporary assumptions and perceptions that perpetuate this lowly status. If we as educators (and a society for that matter) are to achieve excellence in education we must be willing to engage in critical self reflection and analysis about the means by which we prepare teachers and engage in educational research and policy making. The Trouble with Ed Schools serves well as an impetus for such reflection and analysis