Hadronic Light-by-Light Contribution to Muon g-2 in Chiral Perturbation Theory

We compute the hadronic light-by-light scattering contributions to the muon anomalous magnetic moment, \amulbl, in chiral perturbation theory that are enhanced by large logarithms and a factor of $N_C$. They depend on a low-energy constant entering pseudoscalar meson decay into a charged lepton pair. The uncertainty introduced by this constant is $\pm 60\times 10^{-11}$, which is comparable in magnitude to the present uncertainty entering the leading-order vacuum polarization contributions to the anomalous moment. It may be reduced to some extent through an improved measurement of the $\pi^0\to e^+ e^-$ branching ratio. However, the dependence of \amulbl on non-logarithmically enhanced effects cannot be constrained except through the measurement of the anomalous moment itself. The extraction of information on new physics would require a future experimental value for the anomalous moment differing significantly from the 2001 result reported by the E821 collaboration.Comment: 7 pages, 2 figure

Non-locality and Medium Effects in the Exclusive Photoproduction of Eta Mesons on Nuclei

A relativistic model for the quasifree exclusive photoproduction of $\eta$ mesons on nuclei is extended to include both non-local and medium effects. The reaction is assumed to proceed via the dominant contribution of the S$_{11}$(1535) resonance. The complicated integrals resulting from the non-locality are simplified using a modified version of a method given by Cooper and Maxwell. The non-locality effects are found to affect the magnitude of the cross section. Some possibilities reflecting the effects of the medium on the propagation and properties of the intermediate S$_{11}$ resonance are studied. The effects of allowing the S$_{11}$ to interact with the medium via mean field scalar and vector potentials are considered. Both broadening of width and reduction in mass of the resonance lead to a suppression of the calculated cross sections.Comment: 19 pages, 7 figure

Methods to create a stringent selection system for mammalian cell lines

The efficient establishment of high protein producing recombinant mammalian cell lines is facilitated by the use of a stringent selection system. Here, we describe two methods to create a stringent selection system based on the Zeocin resistance marker. First, we cloned increasingly longer stretches of DNA, encoding a range of 8–131 amino acids immediately upstream of the Zeocin selection marker gene. The DNA stretches were separated from the open reading frame of the selection marker gene by a stopcodon. The idea behind this was that the translation machinery will first translate the small peptide, stop and then restart at the AUG of the Zeocin marker. This process, however, will become less efficient with increasingly longer stretches of DNA upstream of the Zeocin marker that has to be translated first. This would result in lower levels of the Zeocin selection marker protein and thus a higher selection stringency of the system. Secondly, we performed a genetic screen to identify PCR induced mutations in the Zeocin selection protein that functionally impair the selection marker protein. Both the insertion of increasingly longer peptides and several Zeocin selection protein mutants resulted in a decreasing number of stably transfected colonies that concomitantly displayed higher protein expression levels. When the Zeocin mutants were combined with very short small peptides (8–14 amino acids long), this created a flexible, high stringency selection system. The system allows the rapid establishment of few, but high protein producing mammalian cell lines

Measurements of the Casimir-Lifshitz force in fluids: the effect of electrostatic forces and Debye screening

In this work, we present detailed measurements of the Casimir-Lifshitz force between two gold surfaces (a sphere and a plate) immersed in ethanol and study the effect of residual electrostatic forces, which are dominated by static fields within the apparatus and can be reduced with proper shielding. Electrostatic forces are further reduced by Debye screening through the addition of salt ions to the liquid. Additionally, the salt leads to a reduction of the Casimir-Lifshitz force by screening the zero-frequency contribution to the force; however, the effect is small between gold surfaces at the measured separations and within experimental error. An improved calibration procedure is described and compared to previous methods. Finally, the experimental results are compared to Lifshitz's theory and found to be consistent for the materials used in the experiment.Comment: 11 figures. PRA in pres

Pion pole contribution to hadronic light-by-light scattering and muon anomalous magnetic moment

We derive an analytic result for the pion pole contribution to the light-by-light scattering correction to the anomalous magnetic moment of the muon, $a_\mu = (g_\mu-2)/2$. Using the vector meson dominance model (VMD) for the pion transition form factor, we obtain $a_\mu^{{\rm LBL},\pi^0} = +56 \times 10^{-11}$.Comment: 4 pages, revte

Measurement of the Casimir force between parallel metallic surfaces

We report on the measurement of the Casimir force between conducting surfaces in a parallel configuration. The force is exerted between a silicon cantilever coated with chromium and a similar rigid surface and is detected looking at the shifts induced in the cantilever frequency when the latter is approached. The scaling of the force with the distance between the surfaces was tested in the 0.5 - 3.0 $\mu$m range, and the related force coefficient was determined at the 15% precision level.Comment: 4 Figure

Improved Precision Measurement of the Casimir Force

We report an improved precision measurement of the Casimir force. The force is measured between a large Al coated sphere and flat plate using an Atomic Force Microscope. The primary experimental improvements include the use of smoother metal coatings, reduced noise, lower systematic errors and independent measurement of surface separations. Also the complete dielectric spectrum of the metal is used in the theory. The average statistical precision remains at the same 1% of the forces measured at the closest separation

Higgs-mediated leptonic decays of B_s and B_d mesons as probes of supersymmetry

If tan(beta) is large, down-type quark mass matrices and Yukawa couplings cannot be simultaneously diagonalized, and flavour violating couplings of the neutral Higgs bosons are induced at the 1-loop level. These couplings lead to Higgs-mediated contributions to the decays B_s -> mu+ mu- and B_d -> tau+ tau-, at a level that might be of interest for the current Tevatron run, or possibly, at B-factories. We evaluate the branching ratios for these decays within the framework of minimal gravity-, gauge- and anomaly-mediated SUSY breaking models, and also in SU(5) supergravity models with non-universal gaugino mass parameters at the GUT scale. We find that the contribution from gluino loops, which seems to have been left out in recent phenomenological analyses, is significant. We explore how the branching fraction varies in these models, emphasizing parameter regions consistent with other observations.Comment: Revised to accommodate minor changes in original text and update reference

A standard set of outcome measures for the comprehensive assessment of oral health and occlusion in individuals with osteogenesis imperfecta

Background: Osteogenesis imperfecta (OI) is a group of inherited connective tissue disorders of varying severity characterized by bone fragility. The primary objective of this international multidisciplinary collaboration initiative was to reach a consensus for a standardized set of clinician and patient-reported outcome measures, as well as associated measuring instruments for dental care of individuals with OI, based on the aspects considered important by both experts and patients. This project is a subsequent to the Key4OI project initiated by the Care4BrittleBones foundation which aims to develop a standard set of outcome measures covering a large domain of factors affecting quality of life for people with OI. An international team of experts comprising orthodontists, pediatric dentists, oral and maxillofacial surgeons, and prosthetic dentists used a modified Delphi consensus process to select clinician-reported outcome measures (CROMs) and patient-reported outcome measures (PROMs) to evaluate oral health in individuals with OI. Important domains were identified through a literature review and by professional expertise (both CROMs and PROMs). In three focus groups of individuals with OI, important and relevant issues regarding dental health were identified. The input from the focus groups was used as the basis for the final set of outcome measures: the selected issues were attributed to relevant CROMs and, when appropriate, matched with validated questionnaires to establish the final PROMs which represented best the specific oral health-related concerns of individuals with OI. Results: Consensus was reached on selected CROMs and PROMs for a standard set of outcome measures and measuring instruments of oral health in individuals with OI. Conclusions: Our project resulted in consensus statements for standardization oral health PROMs and CROMs in individuals with OI. This outcome set can improve the standard of care by incorporating recommendations of professionals involved in dental care of individuals with OI. Further, it can facilitate research and international research co-operation. In addition, the significant contribution of the focus groups highlights the relevance of dental and oral health-related problems of individuals with OI

Complete roughness and conductivity corrections for the recent Casimir force measurement

We consider detailed roughness and conductivity corrections to the Casimir force in the recent Casimir force measurement employing an Atomic Force Microscope. The roughness of the test bodies-a metal plate and a sphere- was investigated with the Atomic Force Microscope and the Scanning Electron Microscope respectively. It consists of separate crystals of different heights and a stochastic background. The amplitude of roughness relative to the zero roughness level was determined and the corrections to the Casimir force were calculated up to the fourth order in a small parameter (which is this amplitude divided by the distance between the two test bodies). Also the corrections due to finite conductivity were found up to the fourth order in relative penetration depth of electromagnetic zero point oscillations into the metal. The theoretical result for the configuration of a sphere above a plate taking into account both corrections is in excellent agreement with the measured Casimir force