Effect of encainide and flecainide on chronic ectopic atrial tachycardia

In the treatment of chronic ectopic atrial tachycardia, standard antiarrhythmic therapy has been shown to be ineffective in the majority of patients. The intravenous and oral effects of two class IC antiarrhythmic drugs, encainide and flecainide, in five patients with chronic ectopic atrial tachycardia were studied using exercise testing, 24 hour long-term electrocardiography and programmed electrical stimulation. All patients had been treated unsuccessfully with at least four antiarrhythmic drugs. In two patients tachycardia was persistent, and in three patients tachycardia occurred intermittently for more than 12 hours/day.Intravenous encainide and flecainide at doses ranging from 0.3 to 2.0 mg/kg and from 0.5 to 1.5 mg/kg body weight, respectively, terminated atrial ectopic tachycardia in all patients. Oral encainide, 150 to 225 mg/day, completely suppressed ectopic atrial activity in four patients during a mean follow-up period of 8 ± 3 months. In the remaining patient encainide markedly reduced the number of episodes of tachycardia. In three patients encainide had to be withdrawn because of intolerable side effects. These patients were well controlled with oral flecainide, 200 to 300 mg/day, without side effects.On the basis of these results, the efficacy of encainide and flecainide in the treatment of chronic ectopic atrial tachycardia appears to be not drug-specific but rather a general class IC property

United States Navy Memorial

General view of bronze sculpture "The Lone Sailor"; Congress authorized the Memorial in 1980, with the stipulation that funding come solely from private contributions. The United States Navy Memorial is home to the Memorial Plaza, which features Stanley Bleifield's statue, The Lone Sailor. The Lone Sailor, a tribute to all personnel of the sea services, overlooks the Granite Sea, an exact replication of the world's oceans. Surrounding the Granite Sea are two fountain pools, honoring the personnel of the American Navy and the other navies of the world. The southern hemisphere of the Granite Sea is surrounded by 26 bronze bas-reliefs commemorating events, personnel, and communities of the various sea services. Adjacent to the Memorial Plaza is the Naval Heritage Center, which features the Arleigh Burke Theater, several rotating exhibits about the sea services, and houses several Navy Log kiosks, for easy registration on the Navy Log. The Naval Heritage Center also features daily screenings of the films At Sea and A Day in the Life of the Blue Angels. The Media Resource Center provides a library of printed, audio and video historical documents on the Navy and The Navy Log room has touch-screen kiosks to register and search for Sea Service members and veterans. Source: Wikipedia; http://en.wikipedia.org/wiki/Main_Page (accessed 7/17/2008

United States Navy Memorial

View of left wing of Memorial, from the south entrance; Congress authorized the Memorial in 1980, with the stipulation that funding come solely from private contributions. The United States Navy Memorial is home to the Memorial Plaza, which features Stanley Bleifield's statue, The Lone Sailor. The Lone Sailor, a tribute to all personnel of the sea services, overlooks the Granite Sea, an exact replication of the world's oceans. Surrounding the Granite Sea are two fountain pools, honoring the personnel of the American Navy and the other navies of the world. The southern hemisphere of the Granite Sea is surrounded by 26 bronze bas-reliefs commemorating events, personnel, and communities of the various sea services. Adjacent to the Memorial Plaza is the Naval Heritage Center, which features the Arleigh Burke Theater, several rotating exhibits about the sea services, and houses several Navy Log kiosks, for easy registration on the Navy Log. The Naval Heritage Center also features daily screenings of the films At Sea and A Day in the Life of the Blue Angels. The Media Resource Center provides a library of printed, audio and video historical documents on the Navy and The Navy Log room has touch-screen kiosks to register and search for Sea Service members and veterans. Source: Wikipedia; http://en.wikipedia.org/wiki/Main_Page (accessed 7/17/2008

United States Navy Memorial

View of reliefs depicting "Naval Aviation - First Shipboard Takeoff" (left) and "Inland Naval Engagements" (center); Congress authorized the Memorial in 1980, with the stipulation that funding come solely from private contributions. The United States Navy Memorial is home to the Memorial Plaza, which features Stanley Bleifield's statue, The Lone Sailor. The Lone Sailor, a tribute to all personnel of the sea services, overlooks the Granite Sea, an exact replication of the world's oceans. Surrounding the Granite Sea are two fountain pools, honoring the personnel of the American Navy and the other navies of the world. The southern hemisphere of the Granite Sea is surrounded by 26 bronze bas-reliefs commemorating events, personnel, and communities of the various sea services. Adjacent to the Memorial Plaza is the Naval Heritage Center, which features the Arleigh Burke Theater, several rotating exhibits about the sea services, and houses several Navy Log kiosks, for easy registration on the Navy Log. The Naval Heritage Center also features daily screenings of the films At Sea and A Day in the Life of the Blue Angels. The Media Resource Center provides a library of printed, audio and video historical documents on the Navy and The Navy Log room has touch-screen kiosks to register and search for Sea Service members and veterans. Source: Wikipedia; http://en.wikipedia.org/wiki/Main_Page (accessed 7/17/2008

United States Navy Memorial

Close view of bas-relief depicting "Admiral David Farragut - Mobile Bay - 1864" ("Damn The Torpedoes - Full Speed Ahead"); Congress authorized the Memorial in 1980, with the stipulation that funding come solely from private contributions. The United States Navy Memorial is home to the Memorial Plaza, which features Stanley Bleifield's statue, The Lone Sailor. The Lone Sailor, a tribute to all personnel of the sea services, overlooks the Granite Sea, an exact replication of the world's oceans. Surrounding the Granite Sea are two fountain pools, honoring the personnel of the American Navy and the other navies of the world. The southern hemisphere of the Granite Sea is surrounded by 26 bronze bas-reliefs commemorating events, personnel, and communities of the various sea services. Adjacent to the Memorial Plaza is the Naval Heritage Center, which features the Arleigh Burke Theater, several rotating exhibits about the sea services, and houses several Navy Log kiosks, for easy registration on the Navy Log. The Naval Heritage Center also features daily screenings of the films At Sea and A Day in the Life of the Blue Angels. The Media Resource Center provides a library of printed, audio and video historical documents on the Navy and The Navy Log room has touch-screen kiosks to register and search for Sea Service members and veterans. Source: Wikipedia; http://en.wikipedia.org/wiki/Main_Page (accessed 7/17/2008

United States Navy Memorial

Close view of bas-relief depicting "Navy Chaplains" ("Eternal Father Strong To Save"); Congress authorized the Memorial in 1980, with the stipulation that funding come solely from private contributions. The United States Navy Memorial is home to the Memorial Plaza, which features Stanley Bleifield's statue, The Lone Sailor. The Lone Sailor, a tribute to all personnel of the sea services, overlooks the Granite Sea, an exact replication of the world's oceans. Surrounding the Granite Sea are two fountain pools, honoring the personnel of the American Navy and the other navies of the world. The southern hemisphere of the Granite Sea is surrounded by 26 bronze bas-reliefs commemorating events, personnel, and communities of the various sea services. Adjacent to the Memorial Plaza is the Naval Heritage Center, which features the Arleigh Burke Theater, several rotating exhibits about the sea services, and houses several Navy Log kiosks, for easy registration on the Navy Log. The Naval Heritage Center also features daily screenings of the films At Sea and A Day in the Life of the Blue Angels. The Media Resource Center provides a library of printed, audio and video historical documents on the Navy and The Navy Log room has touch-screen kiosks to register and search for Sea Service members and veterans. Source: Wikipedia; http://en.wikipedia.org/wiki/Main_Page (accessed 7/17/2008

United States Navy Memorial

Frontal context view of entire Memorial, depicting location within existing buildings on the north side of Penn. Ave; Congress authorized the Memorial in 1980, with the stipulation that funding come solely from private contributions. The United States Navy Memorial is home to the Memorial Plaza, which features Stanley Bleifield's statue, The Lone Sailor. The Lone Sailor, a tribute to all personnel of the sea services, overlooks the Granite Sea, an exact replication of the world's oceans. Surrounding the Granite Sea are two fountain pools, honoring the personnel of the American Navy and the other navies of the world. The southern hemisphere of the Granite Sea is surrounded by 26 bronze bas-reliefs commemorating events, personnel, and communities of the various sea services. Adjacent to the Memorial Plaza is the Naval Heritage Center, which features the Arleigh Burke Theater, several rotating exhibits about the sea services, and houses several Navy Log kiosks, for easy registration on the Navy Log. The Naval Heritage Center also features daily screenings of the films At Sea and A Day in the Life of the Blue Angels. The Media Resource Center provides a library of printed, audio and video historical documents on the Navy and The Navy Log room has touch-screen kiosks to register and search for Sea Service members and veterans. Source: Wikipedia; http://en.wikipedia.org/wiki/Main_Page (accessed 7/17/2008