Concentration of timolol in aqueous humour

Two groups of twenty patients who were to undergo a routine e.c.c.e. applied eye-drops containing timolol 0.1% or 0.5% twice daily during the week preceding their operation. A third group of twenty patients, using placebo drops, served as control. During the cataract surgery a sample of aqueous was collected. The samples from the timolol 0.1% patient group contained a significantly lower concentration of timolol than those from the timolol 0.5% patient group, but there was considerable overlap

Congenital fistulae of the lacrimal gland

A 36-year-old man had congenital fistulae of the palpebral lobes of the lacrimal glands, with orifices bilaterally in the intermarginal strip of his upper eyelids near the external canthi. The left fistula was cystic and had become chronically inflamed. Because antibiotic therapy was unsuccessful, excision was necessary. Congenital fistulae are extremely rare, forming a lateral and tarsal group, each group having typical characteristics

Cysteamin eyedrops in three patients with nephropathic cystinosis

Cysteamin-PO4 eyedrops 5 mMol/l, given to three patients with nephropathic cystinosis brought a great relief from their photophobia and in two of the three patients a measurable decrease in the glare was shown

Periorbital necrotising fasciitis due to Cryptococcus neoformans in a healthy young man

A case report is presented of a healthy 25-year-old man who developed a periorbital necrotising fasciitis after a trivial trauma with a wooden splinter. Necrotising fasciitis of the eyelids occurs rarely. Cryptococcus neoformans is not described as a causative factor of necrotizing fasciitis. Cryptococcus neoformans usually infects patients with immunodeficiencies, diabetes mellitus or steroid therapy. This patient was healthy and developed a periorbital necrotising fasciitis due to Cryptococcus neoformans