Recurrent shell infall events in a B0.5e star: HD 58978 1979-1988

Infall from the circumstellar envelope onto the bright B0.5 IVe star, HD 58978 was studied. The IUE data indicate that the star was surrounded by a low and moderately ionized circumstellar shell at least 12 times between 1979 and 1988. During 6 of these episodes, the signatures of cool circumstellar material were redshifted with respect to the photosphere by 20 to 80 km/sec. The data indicate that the transition from infall to minimal shell absorption can occur in under 10 days, and are consistent either with infall phases lasting up to 6 months, or with infall episodes shorter than 10 to 15 days. The long term behavior of the shell episodes is compared with variability in the stellar wind

2-D Radiative Transfer in Protostellar Envelopes: I. Effects of Geometry on Class I Sources

We present 2-D radiation transfer models of Class I Protostars and show the effect of including more realistic geometries on the resulting spectral energy distributions and images. We begin with a rotationally flattened infalling envelope as our comparison model, and add a flared disk and bipolar cavity. The disk affects the spectral energy distribution most strongly at edge-on inclinations, causing a broad dip at about 10 um (independent of the silicate feature) due to high extinction and low scattering albedo in this wavelength region. The bipolar cavities allow more direct stellar+disk radiation to emerge into polar directions, and more scattering radiation to emerge into all directions. The wavelength-integrated flux, often interpreted as luminosity, varies with viewing angle, with pole-on viewing angles seeing 2-4 times as much flux as edge-on, depending on geometry. Thus, observational estimates of luminosity should take into account the inclination of a source. The envelopes with cavities are significantly bluer in near-IR and mid-IR color-color plots than those without cavities. Using 1-D models to interpret Class I sources with bipolar cavities would lead to an underestimate of envelope mass and an overestimate of the implied evolutionary state. We compute images at near-, mid-, and far-IR wavelengths. We find that the mid-IR colors and images are sensitive to scattering albedo, and that the flared disk shadows the midplane on large size scales at all wavelengths plotted. Finally, our models produce polarization spectra which can be used to diagnose dust properties, such as albedo variations due to grain growth. Our results of polarization across the 3.1 um ice feature agree well with observations for ice mantles covering 5% of the radius of the grains.Comment: Accepted for publication in ApJ, 37 pages, 13 figures (several figures reduced in quality; find original version at http://gemelli.colorado.edu/~bwhitney/preprints.html

Where's the Doughnut? LBV bubbles and Aspherical Fast Winds

In this paper we address the issue of the origin of LBV bipolar bubbles. Previous studies have explained the shapes of LBV nebulae, such as $\eta$ Car, by invoking the interaction of an isotropic fast wind with a previously deposited, slow aspherical wind (a ``slow torus''). In this paper we focus on the opposite scenario where an aspherical fast wind expands into a previously deposited isotropic slow wind. Using high resolution hydrodynamic simulations, which include the effects of radiative cooling, we have completed a series of numerical experiments to test if and how aspherical fast winds effect wind blown bubble morphologies. Our experiments explore a variety of models for the latitudinal variations of fast wind flow parameters. The simulations demonstrate that aspherical fast winds can produce strongly bipolar outflows. In addition the properties of outflows recover some important aspects of LBV bubbles which the previous "slow torus" models can not.Comment: 23 pages, 6 figures, to appear the Astrophysical Journa

In vitro characterization of engineered red blood cells as viral traps against HIV-1 and SARS-CoV-2

Engineered red blood cells (RBCs) expressing viral receptors could be used therapeutically as viral traps, as RBCs lack nuclei and other organelles required for viral replication. However, expression of viral receptors on RBCs is difficult to achieve since mature erythrocytes lack the cellular machinery to synthesize proteins. Herein, we show that the combination of a powerful erythroid-specific expression system and transgene codon optimization yields high expression levels of the HIV-1 receptors CD4 and CCR5, as well as a CD4-glycophorin A (CD4-GpA) fusion protein in erythroid progenitor cells, which efficiently differentiated into enucleated RBCs. HIV-1 efficiently entered RBCs that co-expressed CD4 and CCR5, but viral entry was not required for neutralization, as CD4 or CD4-GpA expression in the absence of CCR5 was sufficient to potently neutralize HIV-1 and prevent infection of CD4+ T cells in vitro due to the formation of high-avidity interactions with trimeric HIV-1 Env spikes on virions. To facilitate continuous large-scale production of RBC viral traps, we generated erythroblast cell lines stably expressing CD4-GpA or ACE2-GpA fusion proteins, which produced potent RBC viral traps against HIV-1 and SARS-CoV-2. Our in vitro results suggest that this approach warrants further investigation as a potential treatment against acute and chronic viral infections

Discovery of the magnetic field of the B1/B2V star \sigma Lupi

In our search for new magnetic massive stars we use the strongest indirect indicator of a magnetic field in B stars, which is periodic variability of UV stellar wind lines occurring in a velocity range symmetric around zero. Our aim is to obtain follow-up spectropolarimetry to search for a magnetic field in magnetic candidate stars. We quantify UV wind line variability, and analyse its time behaviour. The B1/B2V star sigma Lup emerged as a new magnetic candidate star. AAT spectropolarimetric measurements with SEMPOL were obtained. The stellar wind line variations of sigma Lup are similar to what is known in magnetic B stars, but no periodicity could be determined. We detected a longitudinal magnetic field with varying strength and amplitude of about 100 G with error bars of typically 20 G, which supports an oblique magnetic-rotator configuration. The equivalent width variations of the UV lines, the magnetic and the optical line variations are consistent with the well-known photometric period of 3.02 days, which we identify with the rotation period of the star. Additional observations with ESPaDOnS at CFHT strongly confirmed this discovery, and allowed to determine a precise magnetic period. Further analysis revealed that $\sigma$ Lupi is a helium-strong star, with an enhanced nitrogen abundance and an underabundance of carbon, and has a spotted surface. We conclude that sigma Lup is a magnetic oblique rotator, and is a He-strong star. It is the 4th B star for which a magnetic field is discovered from studying only its wind variability. Like in the other magnetic B stars the wind emission originates in the magnetic equator, with maximum emission occurring when a magnetic pole points towards the Earth. The 3.02 d magnetic rotation period is consistent with the photometric period, with maximum light corresponding to maximum magnetic field. A full paper will be submitted to A&A.Comment: 4 pages, 5 figures, to appear in proceedings with AIP. Stellar polarimetry: From birth to death, Eds. Jennifer Hoffman, Barb Whitney, and Jon Bjorkma

Stagnation and Infall of Dense Clumps in the Stellar Wind of tau Scorpii

Observations of the B0.2V star tau Scorpii have revealed unusual stellar wind characteristics: red-shifted absorption in the far-ultraviolet O VI resonance doublet up to +250 km/s, and extremely hard X-ray emission implying gas at temperatures in excess of 10^7 K. We describe a phenomenological model to explain these properties. We assume the wind of tau Sco consists of two components: ambient gas in which denser clumps are embedded. The clumps are optically thick in the UV resonance lines primarily responsible for accelerating the ambient wind. The reduced acceleration causes the clumps to slow and even infall, all the while being confined by the ram pressure of the outflowing ambient wind. We calculate detailed trajectories of the clumps in the ambient stellar wind, accounting for a line radiation driving force and the momentum deposited by the ambient wind in the form of drag. We show these clumps will fall back towards the star with velocities of several hundred km/sec for a broad range of initial conditions. The infalling clumps produce X-ray emitting plasmas with temperatures in excess of (1-6)x10^7 K in bow shocks at their leading edge. The infalling material explains the peculiar red-shifted absorption wings seen in the O VI doublet. The required mass loss in clumps is 3% - 30% ofthe total mass loss rate. The model developed here can be generally applied to line-driven outflows with clumps or density irregularities. (Abstract Abridged)Comment: To appear in the ApJ (1 May 2000). 24 pages, including 6 embedded figure